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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 1
2002 3
2003 2
2004 1
2005 1
2006 1
2007 3
2008 4
2009 2
2010 1
2011 2
2012 4
2013 5
2014 4
2015 4
2016 2
2017 3
2018 1
2019 5
2020 1
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41 results
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Page 1
Proteolytic ectodomain shedding of membrane proteins in mammals-hardware, concepts, and recent developments.
Lichtenthaler SF, Lemberg MK, Fluhrer R. Lichtenthaler SF, et al. Among authors: fluhrer r. EMBO J. 2018 Aug 1;37(15):e99456. doi: 10.15252/embj.201899456. Epub 2018 Jul 5. EMBO J. 2018. PMID: 29976761 Free PMC article. Review.
Signal peptide peptidase and SPP-like proteases - Possible therapeutic targets?
Mentrup T, Loock AC, Fluhrer R, Schröder B. Mentrup T, et al. Among authors: fluhrer r. Biochim Biophys Acta Mol Cell Res. 2017 Nov;1864(11 Pt B):2169-2182. doi: 10.1016/j.bbamcr.2017.06.007. Epub 2017 Jun 15. Biochim Biophys Acta Mol Cell Res. 2017. PMID: 28624439 Free article. Review.
Atherogenic LOX-1 signaling is controlled by SPPL2-mediated intramembrane proteolysis.
Mentrup T, Theodorou K, Cabrera-Cabrera F, Helbig AO, Happ K, Gijbels M, Gradtke AC, Rabe B, Fukumori A, Steiner H, Tholey A, Fluhrer R, Donners M, Schröder B. Mentrup T, et al. Among authors: fluhrer r. J Exp Med. 2019 Apr 1;216(4):807-830. doi: 10.1084/jem.20171438. Epub 2019 Feb 28. J Exp Med. 2019. PMID: 30819724 Free PMC article.
The intramembrane protease SPPL2c promotes male germ cell development by cleaving phospholamban.
Niemeyer J, Mentrup T, Heidasch R, Müller SA, Biswas U, Meyer R, Papadopoulou AA, Dederer V, Haug-Kröper M, Adamski V, Lüllmann-Rauch R, Bergmann M, Mayerhofer A, Saftig P, Wennemuth G, Jessberger R, Fluhrer R, Lichtenthaler SF, Lemberg MK, Schröder B. Niemeyer J, et al. Among authors: fluhrer r. EMBO Rep. 2019 Mar;20(3):e46449. doi: 10.15252/embr.201846449. Epub 2019 Feb 7. EMBO Rep. 2019. PMID: 30733280 Free PMC article.
Signal Peptide Peptidase-Like 2c (SPPL2c) impairs vesicular transport and cleavage of SNARE proteins.
Papadopoulou AA, Müller SA, Mentrup T, Shmueli MD, Niemeyer J, Haug-Kröper M, von Blume J, Mayerhofer A, Feederle R, Schröder B, Lichtenthaler SF, Fluhrer R. Papadopoulou AA, et al. Among authors: fluhrer r. EMBO Rep. 2019 Mar;20(3):e46451. doi: 10.15252/embr.201846451. Epub 2019 Feb 7. EMBO Rep. 2019. PMID: 30733281 Free PMC article.
Signal peptide peptidase-like 2c impairs vesicular transport and cleaves SNARE proteins.
Papadopoulou AA, Müller SA, Mentrup T, Shmueli MD, Niemeyer J, Haug-Kröper M, von Blume J, Mayerhofer A, Feederle R, Schröder B, Lichtenthaler SF, Fluhrer R. Papadopoulou AA, et al. Among authors: fluhrer r. EMBO Rep. 2019 Mar;20(3):e46451. doi: 10.15252/embr.201846451. Epub 2019 Feb 7. EMBO Rep. 2019. PMID: 32048434 Free article.
Signal peptide peptidase-like 2c impairs vesicular transport and cleaves SNARE proteins.
Papadopoulou AA, Müller SA, Mentrup T, Shmueli MD, Niemeyer J, Haug-Kröper M, von Blume J, Mayerhofer A, Feederle R, Schröder B, Lichtenthaler SF, Fluhrer R. Papadopoulou AA, et al. Among authors: fluhrer r. EMBO Rep. 2019 May;20(5):e48133. doi: 10.15252/embr.201948133. EMBO Rep. 2019. PMID: 31061204 Free PMC article.
Latest emerging functions of SPP/SPPL intramembrane proteases.
Mentrup T, Fluhrer R, Schröder B. Mentrup T, et al. Among authors: fluhrer r. Eur J Cell Biol. 2017 Aug;96(5):372-382. doi: 10.1016/j.ejcb.2017.03.002. Epub 2017 Mar 16. Eur J Cell Biol. 2017. PMID: 28366434 Review.
Physiological functions of SPP/SPPL intramembrane proteases.
Mentrup T, Cabrera-Cabrera F, Fluhrer R, Schröder B. Mentrup T, et al. Among authors: fluhrer r. Cell Mol Life Sci. 2020 Aug;77(15):2959-2979. doi: 10.1007/s00018-020-03470-6. Epub 2020 Feb 12. Cell Mol Life Sci. 2020. PMID: 32052089 Free PMC article. Review.
Mechanism, specificity, and physiology of signal peptide peptidase (SPP) and SPP-like proteases.
Voss M, Schröder B, Fluhrer R. Voss M, et al. Among authors: fluhrer r. Biochim Biophys Acta. 2013 Dec;1828(12):2828-39. doi: 10.1016/j.bbamem.2013.03.033. Biochim Biophys Acta. 2013. PMID: 24099004 Free article. Review.
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