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Direct spatial control of Epac1 by cyclic AMP.
Ponsioen B, Gloerich M, Ritsma L, Rehmann H, Bos JL, Jalink K. Ponsioen B, et al. Among authors: rehmann h. Mol Cell Biol. 2009 May;29(10):2521-31. doi: 10.1128/MCB.01630-08. Epub 2009 Mar 9. Mol Cell Biol. 2009. PMID: 19273589 Free PMC article.
Spatial regulation of cyclic AMP-Epac1 signaling in cell adhesion by ERM proteins.
Gloerich M, Ponsioen B, Vliem MJ, Zhang Z, Zhao J, Kooistra MR, Price LS, Ritsma L, Zwartkruis FJ, Rehmann H, Jalink K, Bos JL. Gloerich M, et al. Among authors: rehmann h. Mol Cell Biol. 2010 Nov;30(22):5421-31. doi: 10.1128/MCB.00463-10. Epub 2010 Sep 20. Mol Cell Biol. 2010. PMID: 20855527 Free PMC article.
Communication between the regulatory and the catalytic region of the cAMP-responsive guanine nucleotide exchange factor Epac.
Rehmann H, Rueppel A, Bos JL, Wittinghofer A. Rehmann H, et al. J Biol Chem. 2003 Jun 27;278(26):23508-14. doi: 10.1074/jbc.M301680200. Epub 2003 Apr 21. J Biol Chem. 2003. PMID: 12707263 Free article.
Epac is inhibited by an intramolecular interaction between the cAMP-binding domain and the catalytic region in the absence of cAMP. cAMP binding is proposed to induce a conformational change, which allows a LID, an alpha-helix at the C-terminal end of the cAMP-binding site, to co …
Epac is inhibited by an intramolecular interaction between the cAMP-binding domain and the catalytic region in the absence of cAMP. cAMP bin …
The RapGEF PDZ-GEF2 is required for maturation of cell-cell junctions.
Dubé N, Kooistra MR, Pannekoek WJ, Vliem MJ, Oorschot V, Klumperman J, Rehmann H, Bos JL. Dubé N, et al. Among authors: rehmann h. Cell Signal. 2008 Sep;20(9):1608-15. doi: 10.1016/j.cellsig.2008.05.006. Epub 2008 May 23. Cell Signal. 2008. PMID: 18585005
8-pCPT-2'-O-Me-cAMP-AM: an improved Epac-selective cAMP analogue.
Vliem MJ, Ponsioen B, Schwede F, Pannekoek WJ, Riedl J, Kooistra MR, Jalink K, Genieser HG, Bos JL, Rehmann H. Vliem MJ, et al. Among authors: rehmann h. Chembiochem. 2008 Sep 1;9(13):2052-4. doi: 10.1002/cbic.200800216. Chembiochem. 2008. PMID: 18633951 No abstract available.
78 results