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Will admixture mapping work to find disease genes?
Reich D, Patterson N. Reich D, et al. Philos Trans R Soc Lond B Biol Sci. 2005 Aug 29;360(1460):1605-7. doi: 10.1098/rstb.2005.1691. Philos Trans R Soc Lond B Biol Sci. 2005. PMID: 16096110 Free PMC article. Review.
Detecting association in a case-control study while correcting for population stratification.
Reich DE, Goldstein DB. Reich DE, et al. Genet Epidemiol. 2001 Jan;20(1):4-16. doi: 10.1002/1098-2272(200101)20:1<4::AID-GEPI2>3.0.CO;2-T. Genet Epidemiol. 2001. PMID: 11119293 Review.
Linkage disequilibrium in the human genome.
Reich DE, Cargill M, Bolk S, Ireland J, Sabeti PC, Richter DJ, Lavery T, Kouyoumjian R, Farhadian SF, Ward R, Lander ES. Reich DE, et al. Nature. 2001 May 10;411(6834):199-204. doi: 10.1038/35075590. Nature. 2001. PMID: 11346797
On the allelic spectrum of human disease.
Reich DE, Lander ES. Reich DE, et al. Trends Genet. 2001 Sep;17(9):502-10. doi: 10.1016/s0168-9525(01)02410-6. Trends Genet. 2001. PMID: 11525833
Quality and completeness of SNP databases.
Reich DE, Gabriel SB, Altshuler D. Reich DE, et al. Nat Genet. 2003 Apr;33(4):457-8. doi: 10.1038/ng1133. Epub 2003 Mar 24. Nat Genet. 2003. PMID: 12652301
Methods for high-density admixture mapping of disease genes.
Patterson N, Hattangadi N, Lane B, Lohmueller KE, Hafler DA, Oksenberg JR, Hauser SL, Smith MW, O'Brien SJ, Altshuler D, Daly MJ, Reich D. Patterson N, et al. Among authors: reich d. Am J Hum Genet. 2004 May;74(5):979-1000. doi: 10.1086/420871. Epub 2004 Apr 14. Am J Hum Genet. 2004. PMID: 15088269 Free PMC article.
A high-density admixture map for disease gene discovery in african americans.
Smith MW, Patterson N, Lautenberger JA, Truelove AL, McDonald GJ, Waliszewska A, Kessing BD, Malasky MJ, Scafe C, Le E, De Jager PL, Mignault AA, Yi Z, De The G, Essex M, Sankale JL, Moore JH, Poku K, Phair JP, Goedert JJ, Vlahov D, Williams SM, Tishkoff SA, Winkler CA, De La Vega FM, Woodage T, Sninsky JJ, Hafler DA, Altshuler D, Gilbert DA, O'Brien SJ, Reich D. Smith MW, et al. Among authors: reich d. Am J Hum Genet. 2004 May;74(5):1001-13. doi: 10.1086/420856. Epub 2004 Apr 14. Am J Hum Genet. 2004. PMID: 15088270 Free PMC article.
Comparison of fine-scale recombination rates in humans and chimpanzees.
Winckler W, Myers SR, Richter DJ, Onofrio RC, McDonald GJ, Bontrop RE, McVean GA, Gabriel SB, Reich D, Donnelly P, Altshuler D. Winckler W, et al. Among authors: reich d. Science. 2005 Apr 1;308(5718):107-11. doi: 10.1126/science.1105322. Epub 2005 Feb 10. Science. 2005. PMID: 15705809
A whole-genome admixture scan finds a candidate locus for multiple sclerosis susceptibility.
Reich D, Patterson N, De Jager PL, McDonald GJ, Waliszewska A, Tandon A, Lincoln RR, DeLoa C, Fruhan SA, Cabre P, Bera O, Semana G, Kelly MA, Francis DA, Ardlie K, Khan O, Cree BA, Hauser SL, Oksenberg JR, Hafler DA. Reich D, et al. Nat Genet. 2005 Oct;37(10):1113-8. doi: 10.1038/ng1646. Epub 2005 Sep 25. Nat Genet. 2005. PMID: 16186815
Principal components analysis corrects for stratification in genome-wide association studies.
Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA, Reich D. Price AL, et al. Among authors: reich d. Nat Genet. 2006 Aug;38(8):904-9. doi: 10.1038/ng1847. Epub 2006 Jul 23. Nat Genet. 2006. PMID: 16862161
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