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Robust and Scalable Angiogenesis Assay of Perfused 3D Human iPSC-Derived Endothelium for Anti-Angiogenic Drug Screening.
van Duinen V, Stam W, Mulder E, Famili F, Reijerkerk A, Vulto P, Hankemeier T, van Zonneveld AJ. van Duinen V, et al. Among authors: reijerkerk a. Int J Mol Sci. 2020 Jul 7;21(13):4804. doi: 10.3390/ijms21134804. Int J Mol Sci. 2020. PMID: 32645937 Free PMC article.
High throughput screening in calcium transient assay to assess cardiotoxicity of compounds using hiPSC-derived cardiomyocytes.
Famili F, Lam TW, van Loenen P, Nacken P, Bras M, Honarnejad S, Jiang Y, Borgdroff V, Bohlen H, Reijerkerk A, Rutjes H, Braam S, Luerman G. Famili F, et al. Among authors: reijerkerk a. J Pharmacol Toxicol Methods. 2019 Sep-Oct;99:106595. doi: 10.1016/j.vascn.2019.05.169. Epub 2019 Oct 17. J Pharmacol Toxicol Methods. 2019. PMID: 31962932 No abstract available.
Standardized and Scalable Assay to Study Perfused 3D Angiogenic Sprouting of iPSC-derived Endothelial Cells In Vitro.
van Duinen V, Stam W, Borgdorff V, Reijerkerk A, Orlova V, Vulto P, Hankemeier T, van Zonneveld AJ. van Duinen V, et al. Among authors: reijerkerk a. J Vis Exp. 2019 Nov 6;(153). doi: 10.3791/59678. J Vis Exp. 2019. PMID: 31762444
Combination of cGMP analogue and drug delivery system provides functional protection in hereditary retinal degeneration.
Vighi E, Trifunović D, Veiga-Crespo P, Rentsch A, Hoffmann D, Sahaboglu A, Strasser T, Kulkarni M, Bertolotti E, van den Heuvel A, Peters T, Reijerkerk A, Euler T, Ueffing M, Schwede F, Genieser HG, Gaillard P, Marigo V, Ekström P, Paquet-Durand F. Vighi E, et al. Among authors: reijerkerk a. Proc Natl Acad Sci U S A. 2018 Mar 27;115(13):E2997-E3006. doi: 10.1073/pnas.1718792115. Epub 2018 Mar 12. Proc Natl Acad Sci U S A. 2018. PMID: 29531030 Free PMC article.
Glutathione conjugation dose-dependently increases brain-specific liposomal drug delivery in vitro and in vivo.
Maussang D, Rip J, van Kregten J, van den Heuvel A, van der Pol S, van der Boom B, Reijerkerk A, Chen L, de Boer M, Gaillard P, de Vries H. Maussang D, et al. Among authors: reijerkerk a. Drug Discov Today Technol. 2016 Jun;20:59-69. doi: 10.1016/j.ddtec.2016.09.003. Epub 2016 Oct 13. Drug Discov Today Technol. 2016. PMID: 27986226
Regulation of brain endothelial barrier function by microRNAs in health and neuroinflammation.
Lopez-Ramirez MA, Reijerkerk A, de Vries HE, Romero IA. Lopez-Ramirez MA, et al. Among authors: reijerkerk a. FASEB J. 2016 Aug;30(8):2662-72. doi: 10.1096/fj.201600435RR. Epub 2016 Apr 26. FASEB J. 2016. PMID: 27118674 Review.
The blood-brain barrier in multiple sclerosis: microRNAs as key regulators.
Kamphuis WW, Derada Troletti C, Reijerkerk A, Romero IA, de Vries HE. Kamphuis WW, et al. Among authors: reijerkerk a. CNS Neurol Disord Drug Targets. 2015;14(2):157-67. doi: 10.2174/1871527314666150116125246. CNS Neurol Disord Drug Targets. 2015. PMID: 25613507 Review.
Astrocyte-derived retinoic acid: a novel regulator of blood-brain barrier function in multiple sclerosis.
Mizee MR, Nijland PG, van der Pol SM, Drexhage JA, van Het Hof B, Mebius R, van der Valk P, van Horssen J, Reijerkerk A, de Vries HE. Mizee MR, et al. Among authors: reijerkerk a. Acta Neuropathol. 2014 Nov;128(5):691-703. doi: 10.1007/s00401-014-1335-6. Epub 2014 Aug 23. Acta Neuropathol. 2014. PMID: 25149081
Glutathione PEGylated liposomal methylprednisolone (2B3-201) attenuates CNS inflammation and degeneration in murine myelin oligodendrocyte glycoprotein induced experimental autoimmune encephalomyelitis.
Lee DH, Rötger C, Appeldoorn CC, Reijerkerk A, Gladdines W, Gaillard PJ, Linker RA. Lee DH, et al. Among authors: reijerkerk a. J Neuroimmunol. 2014 Sep 15;274(1-2):96-101. doi: 10.1016/j.jneuroim.2014.06.025. Epub 2014 Jul 6. J Neuroimmunol. 2014. PMID: 25037177
In vivo MR imaging of intercellular adhesion molecule-1 expression in an animal model of multiple sclerosis.
Blezer EL, Deddens LH, Kooij G, Drexhage J, van der Pol SM, Reijerkerk A, Dijkhuizen RM, de Vries HE. Blezer EL, et al. Among authors: reijerkerk a. Contrast Media Mol Imaging. 2015 Mar-Apr;10(2):111-21. doi: 10.1002/cmmi.1602. Epub 2014 Apr 22. Contrast Media Mol Imaging. 2015. PMID: 24753465 Free article.
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