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Ablation of steroid receptor coactivator-3 resembles the human CACT metabolic myopathy.
York B, Reineke EL, Sagen JV, Nikolai BC, Zhou S, Louet JF, Chopra AR, Chen X, Reed G, Noebels J, Adesina AM, Yu H, Wong LJ, Tsimelzon A, Hilsenbeck S, Stevens RD, Wenner BR, Ilkayeva O, Xu J, Newgard CB, O'Malley BW. York B, et al. Among authors: reineke el. Cell Metab. 2012 May 2;15(5):752-63. doi: 10.1016/j.cmet.2012.03.020. Cell Metab. 2012. PMID: 22560224 Free PMC article.
Research resource: tissue- and pathway-specific metabolomic profiles of the steroid receptor coactivator (SRC) family.
York B, Sagen JV, Tsimelzon A, Louet JF, Chopra AR, Reineke EL, Zhou S, Stevens RD, Wenner BR, Ilkayeva O, Bain JR, Xu J, Hilsenbeck SG, Newgard CB, O'Malley BW. York B, et al. Among authors: reineke el. Mol Endocrinol. 2013 Feb;27(2):366-80. doi: 10.1210/me.2012-1324. Epub 2013 Jan 11. Mol Endocrinol. 2013. PMID: 23315938 Free PMC article.
SRC-2 is an essential coactivator for orchestrating metabolism and circadian rhythm.
Stashi E, Lanz RB, Mao J, Michailidis G, Zhu B, Kettner NM, Putluri N, Reineke EL, Reineke LC, Dasgupta S, Dean A, Stevenson CR, Sivasubramanian N, Sreekumar A, Demayo F, York B, Fu L, O'Malley BW. Stashi E, et al. Among authors: reineke el, reineke lc. Cell Rep. 2014 Feb 27;6(4):633-45. doi: 10.1016/j.celrep.2014.01.027. Epub 2014 Feb 13. Cell Rep. 2014. PMID: 24529706 Free PMC article.
A Sleeping Beauty mutagenesis screen reveals a tumor suppressor role for Ncoa2/Src-2 in liver cancer.
O'Donnell KA, Keng VW, York B, Reineke EL, Seo D, Fan D, Silverstein KA, Schrum CT, Xie WR, Mularoni L, Wheelan SJ, Torbenson MS, O'Malley BW, Largaespada DA, Boeke JD. O'Donnell KA, et al. Among authors: reineke el. Proc Natl Acad Sci U S A. 2012 May 22;109(21):E1377-86. doi: 10.1073/pnas.1115433109. Epub 2012 May 3. Proc Natl Acad Sci U S A. 2012. PMID: 22556267 Free PMC article.
47 results