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Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases.
Massberg S, Grahl L, von Bruehl ML, Manukyan D, Pfeiler S, Goosmann C, Brinkmann V, Lorenz M, Bidzhekov K, Khandagale AB, Konrad I, Kennerknecht E, Reges K, Holdenrieder S, Braun S, Reinhardt C, Spannagl M, Preissner KT, Engelmann B. Massberg S, et al. Among authors: reinhardt c. Nat Med. 2010 Aug;16(8):887-96. doi: 10.1038/nm.2184. Epub 2010 Aug 1. Nat Med. 2010. PMID: 20676107
Disulfide HMGB1 derived from platelets coordinates venous thrombosis in mice.
Stark K, Philippi V, Stockhausen S, Busse J, Antonelli A, Miller M, Schubert I, Hoseinpour P, Chandraratne S, von Brühl ML, Gaertner F, Lorenz M, Agresti A, Coletti R, Antoine DJ, Heermann R, Jung K, Reese S, Laitinen I, Schwaiger M, Walch A, Sperandio M, Nawroth PP, Reinhardt C, Jäckel S, Bianchi ME, Massberg S. Stark K, et al. Among authors: reinhardt c. Blood. 2016 Nov 17;128(20):2435-2449. doi: 10.1182/blood-2016-04-710632. Epub 2016 Aug 29. Blood. 2016. PMID: 27574188 Free PMC article.
Mice deficient in the anti-haemophilic coagulation factor VIII show increased von Willebrand factor plasma levels.
Kiouptsi K, Grill A, Mann A, Döhrmann M, Lillich M, Jäckel S, Malinarich F, Formes H, Manukyan D, Subramaniam S, Khandagale A, Karwot C, Thal SC, Bosmann M, Scharrer I, Jurk K, Reinhardt C. Kiouptsi K, et al. Among authors: reinhardt c. PLoS One. 2017 Aug 24;12(8):e0183590. doi: 10.1371/journal.pone.0183590. eCollection 2017. PLoS One. 2017. PMID: 28837614 Free PMC article.
Platelet-localized FXI promotes a vascular coagulation-inflammatory circuit in arterial hypertension.
Kossmann S, Lagrange J, Jäckel S, Jurk K, Ehlken M, Schönfelder T, Weihert Y, Knorr M, Brandt M, Xia N, Li H, Daiber A, Oelze M, Reinhardt C, Lackner K, Gruber A, Monia B, Karbach SH, Walter U, Ruggeri ZM, Renné T, Ruf W, Münzel T, Wenzel P. Kossmann S, et al. Among authors: reinhardt c. Sci Transl Med. 2017 Feb 1;9(375):eaah4923. doi: 10.1126/scitranslmed.aah4923. Sci Transl Med. 2017. PMID: 28148841
383 results