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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1988 1
1996 1
1997 4
1998 2
1999 2
2000 2
2001 5
2002 1
2003 1
2005 2
2006 2
2007 1
2009 1
2010 1
2012 2
2014 1
2016 2
2017 3
2018 2
2019 2
2020 3
2022 1
2023 2
2024 2

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44 results

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Page 1
DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance.
Schröder M, Renatus M, Liang X, Meili F, Zoller T, Ferrand S, Gauter F, Li X, Sigoillot F, Gleim S, Stachyra TM, Thomas JR, Begue D, Khoshouei M, Lefeuvre P, Andraos-Rey R, Chung B, Ma R, Pinch B, Hofmann A, Schirle M, Schmiedeberg N, Imbach P, Gorses D, Calkins K, Bauer-Probst B, Maschlej M, Niederst M, Maher R, Henault M, Alford J, Ahrne E, Tordella L, Hollingworth G, Thomä NH, Vulpetti A, Radimerski T, Holzer P, Carbonneau S, Thoma CR. Schröder M, et al. Among authors: renatus m. Nat Commun. 2024 Jan 4;15(1):275. doi: 10.1038/s41467-023-44237-4. Nat Commun. 2024. PMID: 38177131 Free PMC article.
Apoptosome: the seven-spoked death machine.
Salvesen GS, Renatus M. Salvesen GS, et al. Among authors: renatus m. Dev Cell. 2002 Mar;2(3):256-7. doi: 10.1016/s1534-5807(02)00137-5. Dev Cell. 2002. PMID: 11879630 Free article. Review.
Discovery of New Binders for DCAF1, an Emerging Ligase Target in the Targeted Protein Degradation Field.
Vulpetti A, Holzer P, Schmiedeberg N, Imbach-Weese P, Pissot-Soldermann C, Hollingworth GJ, Radimerski T, Thoma CR, Stachyra TM, Wojtynek M, Maschlej M, Chau S, Schuffenhauer A, Fernández C, Schröder M, Renatus M. Vulpetti A, et al. Among authors: renatus m. ACS Med Chem Lett. 2023 Jun 2;14(7):949-954. doi: 10.1021/acsmedchemlett.3c00104. eCollection 2023 Jul 13. ACS Med Chem Lett. 2023. PMID: 37465299
Phosphorylation meets proteolysis.
Renatus M, Farady CJ. Renatus M, et al. Structure. 2012 Apr 4;20(4):570-1. doi: 10.1016/j.str.2012.03.006. Epub 2012 Apr 3. Structure. 2012. PMID: 22483104 Free article.
3-Amidinophenylalanine-based inhibitors of urokinase.
Stürzebecher J, Vieweg H, Steinmetzer T, Schweinitz A, Stubbs MT, Renatus M, Wikström P. Stürzebecher J, et al. Among authors: renatus m. Bioorg Med Chem Lett. 1999 Nov 1;9(21):3147-52. doi: 10.1016/s0960-894x(99)00541-7. Bioorg Med Chem Lett. 1999. PMID: 10560742
Discovery of Ligands for TRIM58, a Novel Tissue-Selective E3 Ligase.
Hoegenauer K, An S, Axford J, Benander C, Bergsdorf C, Botsch J, Chau S, Fernández C, Gleim S, Hassiepen U, Hunziker J, Joly E, Keller A, Lopez Romero S, Maher R, Mangold AS, Mickanin C, Mihalic M, Neuner P, Patterson AW, Perruccio F, Roggo S, Scesa J, Schröder M, Shkoza D, Thai B, Vulpetti A, Renatus M, Reece-Hoyes JS. Hoegenauer K, et al. Among authors: renatus m. ACS Med Chem Lett. 2023 Nov 13;14(12):1631-1639. doi: 10.1021/acsmedchemlett.3c00259. eCollection 2023 Dec 14. ACS Med Chem Lett. 2023. PMID: 38116426
Structural determinants of MALT1 protease activity.
Wiesmann C, Leder L, Blank J, Bernardi A, Melkko S, Decock A, D'Arcy A, Villard F, Erbel P, Hughes N, Freuler F, Nikolay R, Alves J, Bornancin F, Renatus M. Wiesmann C, et al. Among authors: renatus m. J Mol Biol. 2012 May 25;419(1-2):4-21. doi: 10.1016/j.jmb.2012.02.018. Epub 2012 Feb 23. J Mol Biol. 2012. PMID: 22366302 Free article.
Crystal structure of the human COP9 signalosome.
Lingaraju GM, Bunker RD, Cavadini S, Hess D, Hassiepen U, Renatus M, Fischer ES, Thomä NH. Lingaraju GM, et al. Among authors: renatus m. Nature. 2014 Aug 14;512(7513):161-5. doi: 10.1038/nature13566. Epub 2014 Jul 16. Nature. 2014. PMID: 25043011
44 results