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Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.
Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, Bazan NG, Bernassola F, Bertrand MJM, Bianchi K, Blagosklonny MV, Blomgren K, Borner C, Boya P, Brenner C, Campanella M, Candi E, Carmona-Gutierrez D, Cecconi F, Chan FK, Chandel NS, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Cohen GM, Conrad M, Cubillos-Ruiz JR, Czabotar PE, D'Angiolella V, Dawson TM, Dawson VL, De Laurenzi V, De Maria R, Debatin KM, DeBerardinis RJ, Deshmukh M, Di Daniele N, Di Virgilio F, Dixit VM, Dixon SJ, Duckett CS, Dynlacht BD, El-Deiry WS, Elrod JW, Fimia GM, Fulda S, García-Sáez AJ, Garg AD, Garrido C, Gavathiotis E, Golstein P, Gottlieb E, Green DR, Greene LA, Gronemeyer H, Gross A, Hajnoczky G, Hardwick JM, Harris IS, Hengartner MO, Hetz C, Ichijo H, Jäättelä M, Joseph B, Jost PJ, Juin PP, Kaiser WJ, Karin M, Kaufmann T, Kepp O, Kimchi A, Kitsis RN, Klionsky DJ, Knight RA, Kumar S, Lee SW, Lemasters JJ, Levine B, Linkermann A, Lipton SA, Lockshin RA, López-Otín C, Lowe SW, Luedde T, Lugli E, MacFarlane M, Madeo F, Malewicz M, Malorni W, Manic G, Marine JC, Martin SJ, Martinou JC, Medema JP, Mehlen P, Meier P, Melino S, Miao EA, Molkentin JD, Moll UM, Muñoz-Pinedo C, Nagata S, Nuñez G, Oberst A, Oren M, Overholtzer M, Pagano M, Panaretakis T, Pasparakis M, Penninger JM, Pereira DM, Pervaiz S, Peter ME, Piacentini M, Pinton P, Prehn JHM, Puthalakath H, Rabinovich GA, Rehm M, Rizzuto R, Rodrigues CMP, Rubinsztein DC, Rudel T, Ryan KM, Sayan E, Scorrano L, Shao F, Shi Y, Silke J, Simon HU, Sistigu A, Stockwell BR, Strasser A, Szabadkai G, Tait SWG, Tang D, Tavernarakis N, Thorburn A, Tsujimoto Y, Turk B, Vanden Berghe T, Vandenabeele P, Vander Heiden MG, Villunger A, Virgin HW, Vousden KH, Vucic D, Wagner EF, Walczak H, Wallach D, Wang Y, Wells JA, Wood W, Yuan J, Zakeri Z, Zhivotovsky B, Zitvogel L, Melino G, Kroemer G. Galluzzi L, et al. Cell Death Differ. 2018 Mar;25(3):486-541. doi: 10.1038/s41418-017-0012-4. Epub 2018 Jan 23. Cell Death Differ. 2018. PMID: 29362479 Free PMC article. Review.
Since the field continues to expand and novel mechanisms that orchestrate multiple cell death pathways are unveiled, we propose an updated classification of cell death subroutines focusing on mechanistic and essential (as opposed to correlative and dispensable) aspects of …
Since the field continues to expand and novel mechanisms that orchestrate multiple cell death pathways are unveiled, we propose an up …
Response to a proposal for an integrative medicine curriculum.
Benjamin PJ, Phillips R, Warren D, Salveson C, Hammerschlag R, Snider P, Haas M, Barrett R, Chapman T, Kaneko R, Martin M, Myer SN, Nedrow A, Niemiec C, O'Bryon D, Ochoa S, Peterson D, Weeks J; ACCAHC/OCCIM Task Force. Benjamin PJ, et al. J Altern Complement Med. 2007 Nov;13(9):1021-33. doi: 10.1089/acm.2006.6388. J Altern Complement Med. 2007. PMID: 18047450
BACKGROUND: A paper entitled "Core Competencies in Integrative Medicine for Medical School Curricula: A proposal," published in Academic Medicine, stimulated a broad discussion among complementary and alternative medicine (CAM) educators. …
BACKGROUND: A paper entitled "Core Competencies in Integrative Medicine for Medical School Curricula: A proposal
Target of MCC950 in Inhibition of NLRP3 Inflammasome Activation: a Literature Review.
Wu D, Chen Y, Sun Y, Gao Q, Li H, Yang Z, Wang Y, Jiang X, Yu B. Wu D, et al. Inflammation. 2020 Feb;43(1):17-23. doi: 10.1007/s10753-019-01098-8. Inflammation. 2020. PMID: 31646445 Review.
MCC950 has been proposed as a specific small molecule inhibitor that can selectively block NLRP3 inflammasome activation. ...However, inhibiting chloride intracellular channel-dependent chloride efflux leads to a modification of inflammatory response, which is simil …
MCC950 has been proposed as a specific small molecule inhibitor that can selectively block NLRP3 inflammasome activation. ...However, …
Online Medical Education in India - Different Challenges and Probable Solutions in the Age of COVID-19.
Nimavat N, Singh S, Fichadiya N, Sharma P, Patel N, Kumar M, Chauhan G, Pandit N. Nimavat N, et al. Adv Med Educ Pract. 2021 Mar 4;12:237-243. doi: 10.2147/AMEP.S295728. eCollection 2021. Adv Med Educ Pract. 2021. PMID: 33692645 Free PMC article. Review.
Search terms included online medical education, COVID19, competency-based medical education. CONCLUSION: This review identified various challenges posed by online education on the current medical curriculum, faced by both faculty members and students, …
Search terms included online medical education, COVID19, competency-based medical education. CONCLUSION: This review identifie …
Defining an enabling environment for those with chronic disease: an integrative review.
Loizeau V, Morvillers JM, Bertrand DP, Kilpatrick K, Rothan-Tondeur M. Loizeau V, et al. BMC Nurs. 2021 Dec 20;20(1):252. doi: 10.1186/s12912-021-00741-w. BMC Nurs. 2021. PMID: 34930230 Free PMC article.
To achieve this, develop an environment to increase an individual's capacity for action seems to be a fundamental step. The aim of this study is to characterize an enabling environment for patients in the context of chronic disease management. METHODS: An integrative
To achieve this, develop an environment to increase an individual's capacity for action seems to be a fundamental step. The aim of th …
The Basis of Structure/Function Claims of Nutraceuticals.
Borchers AT, Keen CL, Gershwin ME. Borchers AT, et al. Clin Rev Allergy Immunol. 2016 Dec;51(3):370-382. doi: 10.1007/s12016-016-8536-9. Clin Rev Allergy Immunol. 2016. PMID: 27122022 Review.
In the United States, as in most of the world, there are large numbers of nutraceuticals that are sold and which people take to boost their immune response. There are, in addition, almost an equal number of products sold to reduce allergies. ...The legally mandated disclai …
In the United States, as in most of the world, there are large numbers of nutraceuticals that are sold and which people take to boost their …
Traditional Chinese Medicine: A Qualitative Study for Reconsidering Nursing Care in the United States.
Conroy SF, Hastings-Tolsma M, Voreis K, Deboskey H. Conroy SF, et al. J Holist Nurs. 2020 Dec;38(4):336-349. doi: 10.1177/0898010120903167. Epub 2020 Feb 2. J Holist Nurs. 2020. PMID: 32008417
Purpose: Traditional Chinese medicine (TCM) proposes the world as a holistic unity of energy. With a long history of use, TCM is generally accepted in the Chinese health care system. Despite growing global interest and use, TCM has received a mixed response f …
Purpose: Traditional Chinese medicine (TCM) proposes the world as a holistic unity of energy. With a long history of use, TCM …
Sorbitol Is a Severity Biomarker for PMM2-CDG with Therapeutic Implications.
Ligezka AN, Radenkovic S, Saraswat M, Garapati K, Ranatunga W, Krzysciak W, Yanaihara H, Preston G, Brucker W, McGovern RM, Reid JM, Cassiman D, Muthusamy K, Johnsen C, Mercimek-Andrews S, Larson A, Lam C, Edmondson AC, Ghesquière B, Witters P, Raymond K, Oglesbee D, Pandey A, Perlstein EO, Kozicz T, Morava E. Ligezka AN, et al. Ann Neurol. 2021 Dec;90(6):887-900. doi: 10.1002/ana.26245. Epub 2021 Oct 26. Ann Neurol. 2021. PMID: 34652821
Leveraging cellular glycoproteome assessment, we provided a systems-level view of treatment efficacy and discovered potential novel biosignatures of therapy response. Epalrestat was well-tolerated and led to significant clinical improvements in the first pediatric patient …
Leveraging cellular glycoproteome assessment, we provided a systems-level view of treatment efficacy and discovered potential novel biosigna …
Nanomedicine-based cancer immunotherapy: recent trends and future perspectives.
Lakshmanan VK, Jindal S, Packirisamy G, Ojha S, Lian S, Kaushik A, Alzarooni AIMA, Metwally YAF, Thyagarajan SP, Do Jung Y, Chouaib S. Lakshmanan VK, et al. Cancer Gene Ther. 2021 Sep;28(9):911-923. doi: 10.1038/s41417-021-00299-4. Epub 2021 Feb 8. Cancer Gene Ther. 2021. PMID: 33558704 Review.
The combination of cancer immunotherapy with efficient functionalized nanosystems has emerged as a beneficial treatment strategy and its use has increased rapidly. The roles of stimuli-responsive nanosystems and nanomedicine-based cancer immunotherapy, a subsidiary discipl …
The combination of cancer immunotherapy with efficient functionalized nanosystems has emerged as a beneficial treatment strategy and its use …
Self-Assembly Dual-Responsive NO Donor Nanoparticles for Effective Cancer Therapy.
Gu G, Chen C, Zhang S, Yin B, Wang J. Gu G, et al. ACS Appl Mater Interfaces. 2021 Nov 3;13(43):50682-50694. doi: 10.1021/acsami.1c12646. Epub 2021 Oct 20. ACS Appl Mater Interfaces. 2021. PMID: 34668695
In order to overcome the deficiencies of the existing NO donors and NO delivery vehicles, a novel strategy was proposed to deliver NO for cancer chemotherapy by the prodrug dimer self-assembly nanoparticles of NO donors. ...The insertion of disulfide linkages promotes the …
In order to overcome the deficiencies of the existing NO donors and NO delivery vehicles, a novel strategy was proposed to deliver NO …
53 results