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Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.
Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, Bazan NG, Bernassola F, Bertrand MJM, Bianchi K, Blagosklonny MV, Blomgren K, Borner C, Boya P, Brenner C, Campanella M, Candi E, Carmona-Gutierrez D, Cecconi F, Chan FK, Chandel NS, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Cohen GM, Conrad M, Cubillos-Ruiz JR, Czabotar PE, D'Angiolella V, Dawson TM, Dawson VL, De Laurenzi V, De Maria R, Debatin KM, DeBerardinis RJ, Deshmukh M, Di Daniele N, Di Virgilio F, Dixit VM, Dixon SJ, Duckett CS, Dynlacht BD, El-Deiry WS, Elrod JW, Fimia GM, Fulda S, García-Sáez AJ, Garg AD, Garrido C, Gavathiotis E, Golstein P, Gottlieb E, Green DR, Greene LA, Gronemeyer H, Gross A, Hajnoczky G, Hardwick JM, Harris IS, Hengartner MO, Hetz C, Ichijo H, Jäättelä M, Joseph B, Jost PJ, Juin PP, Kaiser WJ, Karin M, Kaufmann T, Kepp O, Kimchi A, Kitsis RN, Klionsky DJ, Knight RA, Kumar S, Lee SW, Lemasters JJ, Levine B, Linkermann A, Lipton SA, Lockshin RA, López-Otín C, Lowe SW, Luedde T, Lugli E, MacFarlane M, Madeo F, Malewicz M, Malorni W, Manic G, Marine JC, Martin SJ, Martinou JC, Medema JP, Mehlen P, Meier P, Melino S, Miao EA, Molkentin JD, Moll UM, Muñoz-Pinedo C, Nagata S, Nuñez G, Oberst A, Oren M, Overholtzer M, Pagano M, Panaretakis T, Pasparakis M, Penninger JM, Pereira DM, Pervaiz S, Peter ME, Piacentini M, Pinton P, Prehn JHM, Puthalakath H, Rabinovich GA, Rehm M, Rizzuto R, Rodrigues CMP, Rubinsztein DC, Rudel T, Ryan KM, Sayan E, Scorrano L, Shao F, Shi Y, Silke J, Simon HU, Sistigu A, Stockwell BR, Strasser A, Szabadkai G, Tait SWG, Tang D, Tavernarakis N, Thorburn A, Tsujimoto Y, Turk B, Vanden Berghe T, Vandenabeele P, Vander Heiden MG, Villunger A, Virgin HW, Vousden KH, Vucic D, Wagner EF, Walczak H, Wallach D, Wang Y, Wells JA, Wood W, Yuan J, Zakeri Z, Zhivotovsky B, Zitvogel L, Melino G, Kroemer G. Galluzzi L, et al. Cell Death Differ. 2018 Mar;25(3):486-541. doi: 10.1038/s41418-017-0012-4. Epub 2018 Jan 23. Cell Death Differ. 2018. PMID: 29362479 Free PMC article. Review.
Since the field continues to expand and novel mechanisms that orchestrate multiple cell death pathways are unveiled, we propose an updated classification of cell death subroutines focusing on mechanistic and essential (as opposed to correlative and dispensable) aspects of …
Since the field continues to expand and novel mechanisms that orchestrate multiple cell death pathways are unveiled, we propose an up …
Response to a proposal for an integrative medicine curriculum.
Benjamin PJ, Phillips R, Warren D, Salveson C, Hammerschlag R, Snider P, Haas M, Barrett R, Chapman T, Kaneko R, Martin M, Myer SN, Nedrow A, Niemiec C, O'Bryon D, Ochoa S, Peterson D, Weeks J; ACCAHC/OCCIM Task Force. Benjamin PJ, et al. J Altern Complement Med. 2007 Nov;13(9):1021-33. doi: 10.1089/acm.2006.6388. J Altern Complement Med. 2007. PMID: 18047450
BACKGROUND: A paper entitled "Core Competencies in Integrative Medicine for Medical School Curricula: A proposal," published in Academic Medicine, stimulated a broad discussion among complementary and alternative medicine (CAM) educators. …
BACKGROUND: A paper entitled "Core Competencies in Integrative Medicine for Medical School Curricula: A proposal
Fibromyalgia syndrome in need of effective treatments.
Theoharides TC, Tsilioni I, Arbetman L, Panagiotidou S, Stewart JM, Gleason RM, Russell IJ. Theoharides TC, et al. J Pharmacol Exp Ther. 2015 Nov;355(2):255-63. doi: 10.1124/jpet.115.227298. Epub 2015 Aug 25. J Pharmacol Exp Ther. 2015. PMID: 26306765 Free PMC article. Review.
It is clinically characterized by chronic, nonarticular pain and a heightened response to pressure along with sleep disturbances, fatigue, bowel and bladder abnormalities, and cognitive dysfunction. ...The management of FMS requires a multidimensional approach including pa …
It is clinically characterized by chronic, nonarticular pain and a heightened response to pressure along with sleep disturbances, fat …
That's not what you expect to do as a doctor, you know, you don't expect your patients to die." Death as a learning experience for undergraduate medical students.
Smith-Han K, Martyn H, Barrett A, Nicholson H. Smith-Han K, et al. BMC Med Educ. 2016 Apr 14;16:108. doi: 10.1186/s12909-016-0631-3. BMC Med Educ. 2016. PMID: 27080014 Free PMC article.
This research examined medical students' responses of being involved personally in the death of a patient. METHOD: Ten undergraduate medical students were followed through their three years of clinical medical education. ...Finally, we argue that student learning ab …
This research examined medical students' responses of being involved personally in the death of a patient. METHOD: Ten undergraduate …
The Basis of Structure/Function Claims of Nutraceuticals.
Borchers AT, Keen CL, Gershwin ME. Borchers AT, et al. Clin Rev Allergy Immunol. 2016 Dec;51(3):370-382. doi: 10.1007/s12016-016-8536-9. Clin Rev Allergy Immunol. 2016. PMID: 27122022 Review.
In the United States, as in most of the world, there are large numbers of nutraceuticals that are sold and which people take to boost their immune response. There are, in addition, almost an equal number of products sold to reduce allergies. ...The legally mandated disclai …
In the United States, as in most of the world, there are large numbers of nutraceuticals that are sold and which people take to boost their …
Comparative Network Pharmacology Analysis of Classical TCM Prescriptions for Chronic Liver Disease.
Chen Z, Wang X, Li Y, Wang Y, Tang K, Wu D, Zhao W, Ma Y, Liu P, Cao Z. Chen Z, et al. Front Pharmacol. 2019 Nov 22;10:1353. doi: 10.3389/fphar.2019.01353. eCollection 2019. Front Pharmacol. 2019. PMID: 31824313 Free PMC article.
Here, a computational framework of comparative network pharmacology is firstly proposed and then applied to herbal recipes for CLD disease. The analysis showed that, the three formulae modulate CLD mainly through functional modules of immune response, inflammation, …
Here, a computational framework of comparative network pharmacology is firstly proposed and then applied to herbal recipes for CLD di …
Target of MCC950 in Inhibition of NLRP3 Inflammasome Activation: a Literature Review.
Wu D, Chen Y, Sun Y, Gao Q, Li H, Yang Z, Wang Y, Jiang X, Yu B. Wu D, et al. Inflammation. 2020 Feb;43(1):17-23. doi: 10.1007/s10753-019-01098-8. Inflammation. 2020. PMID: 31646445 Review.
MCC950 has been proposed as a specific small molecule inhibitor that can selectively block NLRP3 inflammasome activation. ...However, inhibiting chloride intracellular channel-dependent chloride efflux leads to a modification of inflammatory response, which is simil …
MCC950 has been proposed as a specific small molecule inhibitor that can selectively block NLRP3 inflammasome activation. ...However, …
The Integrative Regulatory Network of circRNA, microRNA, and mRNA in Atrial Fibrillation.
Jiang S, Guo C, Zhang W, Che W, Zhang J, Zhuang S, Wang Y, Zhang Y, Liu B. Jiang S, et al. Front Genet. 2019 Jun 13;10:526. doi: 10.3389/fgene.2019.00526. eCollection 2019. Front Genet. 2019. PMID: 31249590 Free PMC article.
As a new category of non-coding RNAs (ncRNAs), circular RNAs (circRNAs) have been known as the key of developmental processes, regulation of cell function, pathogenesis of heart diseases and pathological responses which could provide novel sight into the pathogenesis of AF …
As a new category of non-coding RNAs (ncRNAs), circular RNAs (circRNAs) have been known as the key of developmental processes, regulation of …
Traditional Chinese Medicine: A Qualitative Study for Reconsidering Nursing Care in the United States.
Conroy SF, Hastings-Tolsma M, Voreis K, Deboskey H. Conroy SF, et al. J Holist Nurs. 2020 Dec;38(4):336-349. doi: 10.1177/0898010120903167. Epub 2020 Feb 2. J Holist Nurs. 2020. PMID: 32008417
Purpose: Traditional Chinese medicine (TCM) proposes the world as a holistic unity of energy. With a long history of use, TCM is generally accepted in the Chinese health care system. Despite growing global interest and use, TCM has received a mixed response f …
Purpose: Traditional Chinese medicine (TCM) proposes the world as a holistic unity of energy. With a long history of use, TCM …
Spirituality and health: the development of a field.
Puchalski CM, Blatt B, Kogan M, Butler A. Puchalski CM, et al. Acad Med. 2014 Jan;89(1):10-6. doi: 10.1097/ACM.0000000000000083. Acad Med. 2014. PMID: 24280839 Free article.
Spirituality has played a role in health care for centuries, but by the early 20th century, technological advances in diagnosis and treatment overshadowed the more human element of medicine. In response, a core group of medical academics and practitioners launched a …
Spirituality has played a role in health care for centuries, but by the early 20th century, technological advances in diagnosis and treatmen …
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