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Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.
Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, Bazan NG, Bernassola F, Bertrand MJM, Bianchi K, Blagosklonny MV, Blomgren K, Borner C, Boya P, Brenner C, Campanella M, Candi E, Carmona-Gutierrez D, Cecconi F, Chan FK, Chandel NS, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Cohen GM, Conrad M, Cubillos-Ruiz JR, Czabotar PE, D'Angiolella V, Dawson TM, Dawson VL, De Laurenzi V, De Maria R, Debatin KM, DeBerardinis RJ, Deshmukh M, Di Daniele N, Di Virgilio F, Dixit VM, Dixon SJ, Duckett CS, Dynlacht BD, El-Deiry WS, Elrod JW, Fimia GM, Fulda S, García-Sáez AJ, Garg AD, Garrido C, Gavathiotis E, Golstein P, Gottlieb E, Green DR, Greene LA, Gronemeyer H, Gross A, Hajnoczky G, Hardwick JM, Harris IS, Hengartner MO, Hetz C, Ichijo H, Jäättelä M, Joseph B, Jost PJ, Juin PP, Kaiser WJ, Karin M, Kaufmann T, Kepp O, Kimchi A, Kitsis RN, Klionsky DJ, Knight RA, Kumar S, Lee SW, Lemasters JJ, Levine B, Linkermann A, Lipton SA, Lockshin RA, López-Otín C, Lowe SW, Luedde T, Lugli E, MacFarlane M, Madeo F, Malewicz M, Malorni W, Manic G, Marine JC, Marti… See abstract for full author list ➔ Galluzzi L, et al. Cell Death Differ. 2018 Mar;25(3):486-541. doi: 10.1038/s41418-017-0012-4. Epub 2018 Jan 23. Cell Death Differ. 2018. PMID: 29362479 Free PMC article. Review.
Since the field continues to expand and novel mechanisms that orchestrate multiple cell death pathways are unveiled, we propose an updated classification of cell death subroutines focusing on mechanistic and essential (as opposed to correlative and dispensable) aspects of …
Since the field continues to expand and novel mechanisms that orchestrate multiple cell death pathways are unveiled, we propose an up …
Responding to the opioid crisis in North America and beyond: recommendations of the Stanford-Lancet Commission.
Humphreys K, Shover CL, Andrews CM, Bohnert ASB, Brandeau ML, Caulkins JP, Chen JH, Cuéllar MF, Hurd YL, Juurlink DN, Koh HK, Krebs EE, Lembke A, Mackey SC, Larrimore Ouellette L, Suffoletto B, Timko C. Humphreys K, et al. Lancet. 2022 Feb 5;399(10324):555-604. doi: 10.1016/S0140-6736(21)02252-2. Epub 2022 Feb 2. Lancet. 2022. PMID: 35122753 Free PMC article. Review. No abstract available.
Response to a proposal for an integrative medicine curriculum.
Benjamin PJ, Phillips R, Warren D, Salveson C, Hammerschlag R, Snider P, Haas M, Barrett R, Chapman T, Kaneko R, Martin M, Myer SN, Nedrow A, Niemiec C, O'Bryon D, Ochoa S, Peterson D, Weeks J; ACCAHC/OCCIM Task Force. Benjamin PJ, et al. J Altern Complement Med. 2007 Nov;13(9):1021-33. doi: 10.1089/acm.2006.6388. J Altern Complement Med. 2007. PMID: 18047450
BACKGROUND: A paper entitled "Core Competencies in Integrative Medicine for Medical School Curricula: A proposal," published in Academic Medicine, stimulated a broad discussion among complementary and alternative medicine (CAM) educators. …
BACKGROUND: A paper entitled "Core Competencies in Integrative Medicine for Medical School Curricula: A proposal
Integrative Single-Cell and Bulk Transcriptomes Analyses Identify Intrinsic HNSCC Subtypes with Distinct Prognoses and Therapeutic Vulnerabilities.
Dai Y, Wang Z, Xia Y, Li J, Wu Y, Wang Y, Jiang H, Cheng J. Dai Y, et al. Clin Cancer Res. 2023 Aug 1;29(15):2845-2858. doi: 10.1158/1078-0432.CCR-22-3563. Clin Cancer Res. 2023. PMID: 37192003
Here, we sought to define the intrinsic epithelial subtypes for HNSCC by integrative analyses of single-cell and bulk RNA sequencing datasets from multiple cohorts and assess their molecular features and clinical significance. ...Three novel, robust signatures derived from …
Here, we sought to define the intrinsic epithelial subtypes for HNSCC by integrative analyses of single-cell and bulk RNA sequencing …
Defining an enabling environment for those with chronic disease: an integrative review.
Loizeau V, Morvillers JM, Bertrand DP, Kilpatrick K, Rothan-Tondeur M. Loizeau V, et al. BMC Nurs. 2021 Dec 20;20(1):252. doi: 10.1186/s12912-021-00741-w. BMC Nurs. 2021. PMID: 34930230 Free PMC article.
BACKGROUND: Health policies are currently being implemented to cope with the 37% of those affected by chronic disease and 63% of deaths worldwide. Among the proposals, there is accelerating support for greater autonomy for patients, which incorporates several concepts, inc …
BACKGROUND: Health policies are currently being implemented to cope with the 37% of those affected by chronic disease and 63% of deaths worl …
LEADS+ Developmental Model: Proposing a new model based on an integrative conceptual review.
Ramelli S, Lal S, Sherbino J, Dickson G, Chan TM. Ramelli S, et al. Med Educ. 2023 Sep;57(9):857-869. doi: 10.1111/medu.15062. Epub 2023 Mar 14. Med Educ. 2023. PMID: 36813746 Review.
We need improved models that support leaders in navigating the complexity of multiple leadership roles. METHOD: This integrative conceptual review sought to examine leadership and followership constructs and how they intersect with current leadership practices in AHCs. ... …
We need improved models that support leaders in navigating the complexity of multiple leadership roles. METHOD: This integrative conc …
Sorbitol Is a Severity Biomarker for PMM2-CDG with Therapeutic Implications.
Ligezka AN, Radenkovic S, Saraswat M, Garapati K, Ranatunga W, Krzysciak W, Yanaihara H, Preston G, Brucker W, McGovern RM, Reid JM, Cassiman D, Muthusamy K, Johnsen C, Mercimek-Andrews S, Larson A, Lam C, Edmondson AC, Ghesquière B, Witters P, Raymond K, Oglesbee D, Pandey A, Perlstein EO, Kozicz T, Morava E. Ligezka AN, et al. Ann Neurol. 2021 Dec;90(6):887-900. doi: 10.1002/ana.26245. Epub 2021 Oct 26. Ann Neurol. 2021. PMID: 34652821 Free PMC article.
Leveraging cellular glycoproteome assessment, we provided a systems-level view of treatment efficacy and discovered potential novel biosignatures of therapy response. Epalrestat was well-tolerated and led to significant clinical improvements in the first pediatric patient …
Leveraging cellular glycoproteome assessment, we provided a systems-level view of treatment efficacy and discovered potential novel biosigna …
An injectable signal-amplifying device elicits a specific immune response against malignant glioblastoma.
Qiu Q, Chen S, He H, Chen J, Ding X, Wang D, Yang J, Guo P, Li Y, Kim J, Sheng J, Gao C, Yin B, Zheng S, Wang J. Qiu Q, et al. Acta Pharm Sin B. 2023 Dec;13(12):5091-5106. doi: 10.1016/j.apsb.2023.06.010. Epub 2023 Jun 20. Acta Pharm Sin B. 2023. PMID: 38045037 Free PMC article.
Poor immunogenicity and deficient immune infiltrates are two major limitations to an effective cancer-specific immune response. Herein, we propose that an injectable signal-amplifying nanocomposite/hydrogel system consisting of granulocyte-macrophage colony-stimulat …
Poor immunogenicity and deficient immune infiltrates are two major limitations to an effective cancer-specific immune response. Herei …
Traditional Chinese Medicine: A Qualitative Study for Reconsidering Nursing Care in the United States.
Conroy SF, Hastings-Tolsma M, Voreis K, Deboskey H. Conroy SF, et al. J Holist Nurs. 2020 Dec;38(4):336-349. doi: 10.1177/0898010120903167. Epub 2020 Feb 2. J Holist Nurs. 2020. PMID: 32008417
Purpose: Traditional Chinese medicine (TCM) proposes the world as a holistic unity of energy. With a long history of use, TCM is generally accepted in the Chinese health care system. Despite growing global interest and use, TCM has received a mixed response f …
Purpose: Traditional Chinese medicine (TCM) proposes the world as a holistic unity of energy. With a long history of use, TCM …
A narrative orientation for the longitudinal integrated clerkship.
Parkin N, Moore M. Parkin N, et al. Clin Teach. 2023 Oct 12:e13661. doi: 10.1111/tct.13661. Online ahead of print. Clin Teach. 2023. PMID: 37823447
FINDINGS: Two features of the LIC model were not explicitly structurally supported in the programme: integration of learning and experiential perspectives. DISCUSSION: The authors draw on narrative medicine and visual thinking to propose a novel response to t …
FINDINGS: Two features of the LIC model were not explicitly structurally supported in the programme: integration of learning and experientia …
71 results