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Evaluation of proposed oral disposition index measures in relation to the actual disposition index.
Retnakaran R, Qi Y, Goran MI, Hamilton JK. Retnakaran R, et al. Diabet Med. 2009 Dec;26(12):1198-203. doi: 10.1111/j.1464-5491.2009.02841.x. Diabet Med. 2009. PMID: 20002470

Results ISS1-2 and IGI/fasting insulin were strongly correlated with each other (r = 0.82, P < 0.0001). Both measures correlated with the disposition index, with ISSI-2 showing a modestly stronger association (ISSI-2: r = 0.24, P = 0.0003; IGI/fasting insulin:

Results ISS1-2 and IGI/fasting insulin were strongly correlated with each other (r = 0.82, P < 0.0001). Both measures correlated w

C-reactive protein and gestational diabetes: the central role of maternal obesity.
Retnakaran R, Hanley AJ, Raif N, Connelly PW, Sermer M, Zinman B. Retnakaran R, et al. J Clin Endocrinol Metab. 2003 Aug;88(8):3507-12. doi: 10.1210/jc.2003-030186. J Clin Endocrinol Metab. 2003. PMID: 12915627 Clinical Trial.
CRP was significantly correlated with prepregnancy BMI (r = 0.38, P < 0.0001), followed by fasting insulin (r = 0.27, P = 0.0002) and fasting blood glucose (r = 0.18, P = 0.016). ...

CRP was significantly correlated with prepregnancy BMI (r = 0.38, P < 0.0001), followed by fasting insulin (r = 0.27, P = 0

Reduced adiponectin concentration in women with gestational diabetes: a potential factor in progression to type 2 diabetes.
Retnakaran R, Hanley AJ, Raif N, Connelly PW, Sermer M, Zinman B. Retnakaran R, et al. Diabetes Care. 2004 Mar;27(3):799-800. doi: 10.2337/diacare.27.3.799. Diabetes Care. 2004. PMID: 14988306 No abstract available.
Adiponectin and beta cell dysfunction in gestational diabetes: pathophysiological implications.
Retnakaran R, Hanley AJ, Raif N, Hirning CR, Connelly PW, Sermer M, Kahn SE, Zinman B. Retnakaran R, et al. Diabetologia. 2005 May;48(5):993-1001. doi: 10.1007/s00125-005-1710-x. Epub 2005 Mar 19. Diabetologia. 2005. PMID: 15778860
Importantly, adiponectin was significantly correlated with ISSI (r=0.34, p<0.0001), with a stepwise increase in mean ISSI observed per tertile of adiponectin concentration (trend p<0.0001). In multivariate linear regression analysis, ISSI was positively correlated wi …
Importantly, adiponectin was significantly correlated with ISSI (r=0.34, p<0.0001), with a stepwise increase in mean ISSI observed …
Ethnicity modifies the effect of obesity on insulin resistance in pregnancy: a comparison of Asian, South Asian, and Caucasian women.
Retnakaran R, Hanley AJ, Connelly PW, Sermer M, Zinman B. Retnakaran R, et al. J Clin Endocrinol Metab. 2006 Jan;91(1):93-7. doi: 10.1210/jc.2005-1253. Epub 2005 Oct 25. J Clin Endocrinol Metab. 2006. PMID: 16249285
Matsuda and R. DeFronzo, previously validated in pregnancy. RESULTS: There were no significant ethnic differences in insulin sensitivity despite variation in prepregnancy BMI (Caucasians, 25.2 kg/m(2); South Asians, 23.3 kg/m(2); Asians, 21.4 kg/m(2); overall P = 0.0001). …
Matsuda and R. DeFronzo, previously validated in pregnancy. RESULTS: There were no significant ethnic differences in insulin sensitiv …
The impact of insulin resistance on proinsulin secretion in pregnancy: hyperproinsulinemia is not a feature of gestational diabetes.
Retnakaran R, Hanley AJ, Sermer M, Zinman B. Retnakaran R, et al. Diabetes Care. 2005 Nov;28(11):2710-5. doi: 10.2337/diacare.28.11.2710. Diabetes Care. 2005. PMID: 16249544

Using Spearman univariate correlation analysis, fasting proinsulin-to-C-peptide ratio was significantly correlated with IS(OGTT) (r = 0.29, P < 0.0001) and inversely related to the homeostasis model assessment of insulin resistance (r = -0.36, P < 0.0001) and

Using Spearman univariate correlation analysis, fasting proinsulin-to-C-peptide ratio was significantly correlated with IS(OGTT) (r = …
Impaired glucose tolerance of pregnancy is a heterogeneous metabolic disorder as defined by the glycemic response to the oral glucose tolerance test.
Retnakaran R, Zinman B, Connelly PW, Sermer M, Hanley AJ. Retnakaran R, et al. Diabetes Care. 2006 Jan;29(1):57-62. doi: 10.2337/diacare.29.1.57. Diabetes Care. 2006. PMID: 16373896
Nontraditional cardiovascular risk factors in pediatric metabolic syndrome.
Retnakaran R, Zinman B, Connelly PW, Harris SB, Hanley AJ. Retnakaran R, et al. J Pediatr. 2006 Feb;148(2):176-82. doi: 10.1016/j.jpeds.2005.08.025. J Pediatr. 2006. PMID: 16492425
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