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Enhancing antibody Fc heterodimer formation through electrostatic steering effects: applications to bispecific molecules and monovalent IgG.
Gunasekaran K, Pentony M, Shen M, Garrett L, Forte C, Woodward A, Ng SB, Born T, Retter M, Manchulenko K, Sweet H, Foltz IN, Wittekind M, Yan W. Gunasekaran K, et al. Among authors: Retter M. J Biol Chem. 2010 Jun 18;285(25):19637-46. doi: 10.1074/jbc.M110.117382. Epub 2010 Apr 16. J Biol Chem. 2010. PMID: 20400508 Free PMC article.
Anti-PCSK9 antibody pharmacokinetics and low-density lipoprotein-cholesterol pharmacodynamics in nonhuman primates are antigen affinity-dependent and exhibit limited sensitivity to neonatal Fc receptor-binding enhancement.
Henne KR, Ason B, Howard M, Wang W, Sun J, Higbee J, Tang J, Matsuda KC, Xu R, Zhou L, Chan JC, King C, Piper DE, Ketchem RR, Michaels ML, Jackson SM, Retter MW. Henne KR, et al. Among authors: Retter MW. J Pharmacol Exp Ther. 2015 Apr;353(1):119-31. doi: 10.1124/jpet.114.221242. Epub 2015 Feb 4. J Pharmacol Exp Ther. 2015. PMID: 25653417
Placental transfer of a fully human IgG2 monoclonal antibody in the cynomolgus monkey, rat, and rabbit: a comparative assessment from during organogenesis to late gestation.
Moffat GJ, Retter MW, Kwon G, Loomis M, Hock MB, Hall C, Bussiere J, Lewis EM, Chellman GJ. Moffat GJ, et al. Among authors: Retter MW. Birth Defects Res B Dev Reprod Toxicol. 2014 Apr;101(2):178-88. doi: 10.1002/bdrb.21105. Birth Defects Res B Dev Reprod Toxicol. 2014. PMID: 24753333
Impact of glycation on antibody clearance.
Yang J, Primack R, Frohn M, Wang W, Luan P, Retter MW, Flynn GC. Yang J, et al. Among authors: Retter MW. AAPS J. 2015 Jan;17(1):237-44. doi: 10.1208/s12248-014-9694-4. Epub 2014 Nov 21. AAPS J. 2015. PMID: 25413724 Free PMC article.
Homeostasis of human NK cells is not IL-15 dependent.
Lebrec H, Horner MJ, Gorski KS, Tsuji W, Xia D, Pan WJ, Means G, Pietz G, Li N, Retter M, Shaffer K, Patel N, Narayanan PK, Butz EA. Lebrec H, et al. Among authors: Retter M. J Immunol. 2013 Dec 1;191(11):5551-8. doi: 10.4049/jimmunol.1301000. Epub 2013 Nov 1. J Immunol. 2013. PMID: 24184554 Free article.
Investigation of maternal and fetal exposure to an IgG2 monoclonal antibody following biweekly intravaginal administration to cynomolgus monkeys throughout pregnancy.
Moffat GJ, Davies R, Kwon G, Retter MW, Chellman GJ, Kanapuram S, Moore M, Loomis M, Wang W, Pyrah IT. Moffat GJ, et al. Among authors: Retter MW. Reprod Toxicol. 2014 Sep;48:132-7. doi: 10.1016/j.reprotox.2014.05.003. Epub 2014 May 22. Reprod Toxicol. 2014. PMID: 24859271
A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates.
Chan JC, Piper DE, Cao Q, Liu D, King C, Wang W, Tang J, Liu Q, Higbee J, Xia Z, Di Y, Shetterly S, Arimura Z, Salomonis H, Romanow WG, Thibault ST, Zhang R, Cao P, Yang XP, Yu T, Lu M, Retter MW, Kwon G, Henne K, Pan O, Tsai MM, Fuchslocher B, Yang E, Zhou L, Lee KJ, Daris M, Sheng J, Wang Y, Shen WD, Yeh WC, Emery M, Walker NP, Shan B, Schwarz M, Jackson SM. Chan JC, et al. Among authors: Retter MW. Version 2. Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9820-5. doi: 10.1073/pnas.0903849106. Epub 2009 May 14. Proc Natl Acad Sci U S A. 2009. PMID: 19443683 Free PMC article.
Characterization of a proapoptotic antiganglioside GM2 monoclonal antibody and evaluation of its therapeutic effect on melanoma and small cell lung carcinoma xenografts.
Retter MW, Johnson JC, Peckham DW, Bannink JE, Bangur CS, Dresser K, Cai F, Foy TM, Fanger NA, Fanger GR, Woda B, Rock KL. Retter MW, et al. Cancer Res. 2005 Jul 15;65(14):6425-34. doi: 10.1158/0008-5472.CAN-05-0300. Cancer Res. 2005. PMID: 16024647
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