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Gmnc Is a Master Regulator of the Multiciliated Cell Differentiation Program.
Zhou F, Narasimhan V, Shboul M, Chong YL, Reversade B, Roy S. Zhou F, et al. Curr Biol. 2015 Dec 21;25(24):3267-73. doi: 10.1016/j.cub.2015.10.062. Curr Biol. 2015. PMID: 26778655
Gmnc Is a Master Regulator of the Multiciliated Cell Differentiation Program.
Zhou F, Narasimhan V, Shboul M, Chong YL, Reversade B, Roy S. Zhou F, et al. Curr Biol. 2017 Jan 23;27(2):305-307. doi: 10.1016/j.cub.2016.12.051. Curr Biol. 2017. PMID: 28118582 No abstract available.
ELABELA: a hormone essential for heart development signals via the apelin receptor.
Chng SC, Ho L, Tian J, Reversade B. Chng SC, et al. Dev Cell. 2013 Dec 23;27(6):672-80. doi: 10.1016/j.devcel.2013.11.002. Epub 2013 Dec 5. Dev Cell. 2013. PMID: 24316148
RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6.
Szenker-Ravi E, Altunoglu U, Leushacke M, Bosso-Lefèvre C, Khatoo M, Thi Tran H, Naert T, Noelanders R, Hajamohideen A, Beneteau C, de Sousa SB, Karaman B, Latypova X, Başaran S, Yücel EB, Tan TT, Vlaminck L, Nayak SS, Shukla A, Girisha KM, Le Caignec C, Soshnikova N, Uyguner ZO, Vleminckx K, Barker N, Kayserili H, Reversade B. Szenker-Ravi E, et al. Nature. 2018 May;557(7706):564-569. doi: 10.1038/s41586-018-0118-y. Epub 2018 May 16. Nature. 2018. PMID: 29769720
The Apelin receptor enhances Nodal/TGFβ signaling to ensure proper cardiac development.
Deshwar AR, Chng SC, Ho L, Reversade B, Scott IC. Deshwar AR, et al. Elife. 2016 Apr 14;5:e13758. doi: 10.7554/eLife.13758. Elife. 2016. PMID: 27077952 Free PMC article.
Elevating Nodal levels in aplnra/b morphant and double mutant embryos is sufficient to rescue cardiac differentiation defects. ...
Elevating Nodal levels in aplnra/b morphant and double mutant embryos is sufficient to rescue cardiac differentiation defects. ...
Author Correction: RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6.
Szenker-Ravi E, Altunoglu U, Leushacke M, Bosso-Lefèvre C, Khatoo M, Thi Tran H, Naert T, Noelanders R, Hajamohideen A, Beneteau C, de Sousa SB, Karaman B, Latypova X, Başaran S, Yücel EB, Tan TT, Vlaminck L, Nayak SS, Shukla A, Girisha KM, Le Caignec C, Soshnikova N, Uyguner ZO, Vleminckx K, Barker N, Kayserili H, Reversade B. Szenker-Ravi E, et al. Nature. 2018 Sep;561(7722):E7. doi: 10.1038/s41586-018-0296-7. Nature. 2018. PMID: 29977062
De novo mutations in SMCHD1 cause Bosma arhinia microphthalmia syndrome and abrogate nasal development.
Gordon CT, Xue S, Yigit G, Filali H, Chen K, Rosin N, Yoshiura KI, Oufadem M, Beck TJ, McGowan R, Magee AC, Altmüller J, Dion C, Thiele H, Gurzau AD, Nürnberg P, Meschede D, Mühlbauer W, Okamoto N, Varghese V, Irving R, Sigaudy S, Williams D, Ahmed SF, Bonnard C, Kong MK, Ratbi I, Fejjal N, Fikri M, Elalaoui SC, Reigstad H, Bole-Feysot C, Nitschké P, Ragge N, Lévy N, Tunçbilek G, Teo AS, Cunningham ML, Sefiani A, Kayserili H, Murphy JM, Chatdokmaiprai C, Hillmer AM, Wattanasirichaigoon D, Lyonnet S, Magdinier F, Javed A, Blewitt ME, Amiel J, Wollnik B, Reversade B. Gordon CT, et al. Nat Genet. 2017 Feb;49(2):249-255. doi: 10.1038/ng.3765. Epub 2017 Jan 9. Nat Genet. 2017. PMID: 28067911
Structural basis of RIP2 activation and signaling.
Gong Q, Long Z, Zhong FL, Teo DET, Jin Y, Yin Z, Boo ZZ, Zhang Y, Zhang J, Yang R, Bhushan S, Reversade B, Li Z, Wu B. Gong Q, et al. Nat Commun. 2018 Nov 26;9(1):4993. doi: 10.1038/s41467-018-07447-9. Nat Commun. 2018. PMID: 30478312 Free PMC article.
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