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Phase IIa randomized placebocontrolled clinical trial to evaluate the efficacy of bromhexine in combination with standard therapy in the early treatment of COVID-19 in primary care patients.
Ramírez D, Rojas R, Fierro H, Nova DA, Renard GM, Ampuero E, Fuentealba J, Martínez A, Gil C, Reyes-Parada M. Ramírez D, et al. Among authors: reyes parada m. Rev Med Chil. 2024 Dec;152(12):1198-1208. doi: 10.4067/s0034-98872024001201198. Rev Med Chil. 2024. PMID: 40178212 Free article. Clinical Trial.
Psychostimulants and social behaviors.
Cid-Jofré V, Bahamondes T, Zúñiga Correa A, Ahumada Arias I, Reyes-Parada M, Renard GM. Cid-Jofré V, et al. Among authors: reyes parada m. Front Pharmacol. 2024 Apr 25;15:1364630. doi: 10.3389/fphar.2024.1364630. eCollection 2024. Front Pharmacol. 2024. PMID: 38725665 Free PMC article. Review.
Identification of Potential Multitarget Directed Ligands for Alzheimer's Disease by Coupling Virtual Screening and Experimental Validation.
Valenzuela-Hormazábal P, Valero-Rojas J, Martínez-González L, Ramos-Inza S, Oviedo-Pino V, González-Ortega C, Hernando G, López JJ, Scorza C, Echeverry C, Gutierrez M, Reyes-Parada M, Martínez A, Ramírez D. Valenzuela-Hormazábal P, et al. Among authors: reyes parada m. J Chem Inf Model. 2026 Mar 9;66(5):2900-2917. doi: 10.1021/acs.jcim.5c02202. Epub 2026 Feb 23. J Chem Inf Model. 2026. PMID: 41728859
Distinct Swimming Behavioral Phenotypes Following Serotonin and Dopamine Transporter Modulation in the Adult Zebrafish Novel Tank Diving Test (NTT).
Farías-Cea A, Pérez L, Leal C, Segura K, Hernández V, Atiés-Pérez C, Martínez LM, Hödar-Salazar M, Reyes-Parada M, Sotomayor-Zárate R, Rojas-Hidalgo F, Julio-Pieper M, Bravo JA, Borroto-Escuela DO, Iturriaga-Vásquez P. Farías-Cea A, et al. Among authors: reyes parada m. Pharmaceuticals (Basel). 2025 Nov 27;18(12):1807. doi: 10.3390/ph18121807. Pharmaceuticals (Basel). 2025. PMID: 41471296 Free PMC article.
Design, Synthesis, and Evaluation of 1-Benzylpiperidine and 1-Benzoylpiperidine Derivatives as Dual-Target Inhibitors of Acetylcholinesterase and Serotonin Transporter for Alzheimer's Disease.
González-Gutiérrez JP, Castillo-Ríos D, Ríos-Campos V, González-Gutiérrez IA, Flores Melivilu D, Hormazábal Uribe E, Moraga-Nicolás F, Segura K, Hernández V, Farías-Cea A, Pessoa-Mahana HA, Reyes-Parada MI, Iturriaga-Vásquez P. González-Gutiérrez JP, et al. Among authors: reyes parada mi. Molecules. 2025 Jul 21;30(14):3047. doi: 10.3390/molecules30143047. Molecules. 2025. PMID: 40733311 Free PMC article.
A New Strategy for Multitarget Drug Discovery/Repositioning Through the Identification of Similar 3D Amino Acid Patterns Among Proteins Structures: The Case of Tafluprost and its Effects on Cardiac Ion Channels.
Valdés-Jiménez A, Jiménez-González D, Kiper AK, Rinné S, Decher N, González W, Reyes-Parada M, Núñez-Vivanco G. Valdés-Jiménez A, et al. Among authors: reyes parada m. Front Pharmacol. 2022 Mar 18;13:855792. doi: 10.3389/fphar.2022.855792. eCollection 2022. Front Pharmacol. 2022. PMID: 35370665 Free PMC article.
63 results