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Intra- and extracellular β-amyloid overexpression via adeno-associated virus-mediated gene transfer impairs memory and synaptic plasticity in the hippocampus.
Forner S, Martini AC, Prieto GA, Dang CT, Rodriguez-Ortiz CJ, Reyes-Ruiz JM, Trujillo-Estrada L, da Cunha C, Andrews EJ, Phan J, Vu Ha J, Chang AVZD, Levites Y, Cruz PE, Ager R, Medeiros R, Kitazawa M, Glabe CG, Cotman CW, Golde T, Baglietto-Vargas D, LaFerla FM. Forner S, et al. Sci Rep. 2019 Nov 4;9(1):15936. doi: 10.1038/s41598-019-52324-0. Sci Rep. 2019. PMID: 31685865 Free PMC article.
Early long-term administration of the CSF1R inhibitor PLX3397 ablates microglia and reduces accumulation of intraneuronal amyloid, neuritic plaque deposition and pre-fibrillar oligomers in 5XFAD mouse model of Alzheimer's disease.
Sosna J, Philipp S, Albay R 3rd, Reyes-Ruiz JM, Baglietto-Vargas D, LaFerla FM, Glabe CG. Sosna J, et al. Mol Neurodegener. 2018 Mar 1;13(1):11. doi: 10.1186/s13024-018-0244-x. Mol Neurodegener. 2018. PMID: 29490706 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 33461949
GABAergic drugs and Alzheimer's disease.
Limon A, Reyes-Ruiz JM, Miledi R. Limon A, et al. Future Med Chem. 2011 Feb;3(2):149-53. doi: 10.4155/fmc.10.291. Future Med Chem. 2011. PMID: 21428809 No abstract available.
60 results