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Serendipity in anticancer drug discovery.
Hargrave-Thomas E, Yu B, Reynisson J. Hargrave-Thomas E, et al. World J Clin Oncol. 2012 Jan 10;3(1):1-6. doi: 10.5306/wjco.v3.i1.1. World J Clin Oncol. 2012. PMID: 22247822 Free PMC article.
Generation of Quality Hit Matter for Successful Drug Discovery Projects.
Reynisson J. Reynisson J. Molecules. 2019 Jan 22;24(3):381. doi: 10.3390/molecules24030381. Molecules. 2019. PMID: 30678174 Free PMC article.
Discovery of novel phosphatidylcholine-specific phospholipase C drug-like inhibitors as potential anticancer agents.
Eurtivong C, Pilkington LI, van Rensburg M, White RM, Brar HK, Rees S, Paulin EK, Xu CS, Sharma N, Leung IKH, Leung E, Barker D, Reynisson J. Eurtivong C, et al. Eur J Med Chem. 2020 Feb 1;187:111919. doi: 10.1016/j.ejmech.2019.111919. Epub 2019 Nov 27. Eur J Med Chem. 2020. PMID: 31810783
The effect of PLC-γ2 inhibitors on the growth of human tumour cells.
Feng L, Reynisdóttir I, Reynisson J. Feng L, et al. Eur J Med Chem. 2012 Aug;54:463-9. doi: 10.1016/j.ejmech.2012.05.029. Epub 2012 May 31. Eur J Med Chem. 2012. PMID: 22698703
From Catalysis to Cancer: Toward Structure-Activity Relationships for Benzimidazol-2-ylidene-Derived N-Heterocyclic-Carbene Complexes as Anticancer Agents.
Lam NYS, Truong D, Burmeister H, Babak MV, Holtkamp HU, Movassaghi S, Ayine-Tora DM, Zafar A, Kubanik M, Oehninger L, Söhnel T, Reynisson J, Jamieson SMF, Gaiddon C, Ott I, Hartinger CG. Lam NYS, et al. Inorg Chem. 2018 Nov 19;57(22):14427-14434. doi: 10.1021/acs.inorgchem.8b02634. Epub 2018 Nov 8. Inorg Chem. 2018. PMID: 30406647
Investigation of the incidence of "undesirable" molecular moieties for high-throughput screening compound libraries in marketed drug compounds.
Axerio-Cilies P, Castañeda IP, Mirza A, Reynisson J. Axerio-Cilies P, et al. Eur J Med Chem. 2009 Mar;44(3):1128-34. doi: 10.1016/j.ejmech.2008.06.013. Epub 2008 Jun 26. Eur J Med Chem. 2009. PMID: 18692938
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