Human myeloperoxidase (hMPO) is expressed in neurons in the substantia nigra in Parkinson's disease and in the hMPO-α-synuclein-A53T mouse model, correlating with increased nitration and aggregation of α-synuclein and exacerbation of motor impairment.
Free Radic Biol Med. 2019 Sep;141:115-140. doi: 10.1016/j.freeradbiomed.2019.05.033. Epub 2019 Jun 6.
Free Radic Biol Med. 2019.
PMID: 31175983
Free PMC article.