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Therapeutic Anticancer Uses of the Active Principles of "Rhopalurus junceus" Venom.
Dioguardi M, Caloro GA, Laino L, Alovisi M, Sovereto D, Crincoli V, Aiuto R, Dioguardi A, De Lillo A, Troiano G, Lo Muzio L. Dioguardi M, et al. Biomedicines. 2020 Sep 27;8(10):382. doi: 10.3390/biomedicines8100382. Biomedicines. 2020. PMID: 32992456 Free PMC article. Review.
The Rhopalurus junceus is a scorpion belonging to the Buthidae family that finds its habitat in Cuba. ...
The Rhopalurus junceus is a scorpion belonging to the Buthidae family that finds its habitat in Cuba. ...
Rhopalurus junceus scorpion venom induces antitumor effect in vitro and in vivo against a murine mammary adenocarcinoma model.
Díaz-García A, Ruiz-Fuentes JL, Frión-Herrera Y, Yglesias-Rivera A, Garlobo YR, Sánchez HR, Aurrecochea JCR, López Fuentes LX. Díaz-García A, et al. Iran J Basic Med Sci. 2019 Jul;22(7):759-765. doi: 10.22038/ijbms.2019.33308.7956. Iran J Basic Med Sci. 2019. PMID: 32373297 Free PMC article.
OBJECTIVES: In Cuba the endemic scorpion species Rhopalurus junceus has been used in traditional medicine for cancer treatment and related diseases. ...
OBJECTIVES: In Cuba the endemic scorpion species Rhopalurus junceus has been used in traditional medicine for cancer treatment …
Rhopalurus junceus scorpion venom induces apoptosis in the triple negative human breast cancer cell line MDA-MB-231.
Díaz-García A, Ruiz-Fuentes JL, Rodríguez-Sánchez H, Fraga Castro JA. Díaz-García A, et al. J Venom Res. 2017 Apr 16;8:9-13. eCollection 2017. J Venom Res. 2017. PMID: 29285349 Free PMC article.
Rhopalurus junceus scorpion venom has demonstrated high cytotoxic activity in epithelial cancer cells. ...The overall effect indicates that the selective cytotoxic effect of the scorpion venom is associated with its apoptosis-inducing effect through the mitochondria
Rhopalurus junceus scorpion venom has demonstrated high cytotoxic activity in epithelial cancer cells. ...The overall effect i
Pharmacokinetics and Biodistribution of Rhopalurus junceus Scorpion Venom in Tumor-Bearing Mice after Intravenous and Oral Administration.
Díaz-García A, Pimentel González G, Basaco Bernabeu T, Rodríguez Aurrecochea JC, Rodríguez Sánchez H, Sánchez Monzón I, Hernández Gómez M, Rodríguez Torres C, Regla Rodríguez Capote M, Guevara Orellanes I. Díaz-García A, et al. Iran Biomed J. 2019 Jul;23(4):287-96. doi: 10.29252/.23.4.287. Epub 2019 Apr 7. Iran Biomed J. 2019. PMID: 30954030 Free PMC article.
BACKGROUND: Rhopalurus junceus scorpion venom has shown potential for anticancer treatment. ...In tumor tissue, after the maximum uptake for both routes, there was a consistent behavior of radioactivity respect to the major organs during the first 480 min. CONCLUSIO …
BACKGROUND: Rhopalurus junceus scorpion venom has shown potential for anticancer treatment. ...In tumor tissue, after the maxi …
Safety evaluation of the venom from scorpion Rhopalurus junceus: Assessment of oral short term, subchronic toxicity and teratogenic effect.
Lagarto A, Bueno V, Pérez MR, Rodríguez CC, Guevara I, Valdés O, Bellma A, Gabilondo T, Padrón AS. Lagarto A, et al. Toxicon. 2020 Mar;176:59-66. doi: 10.1016/j.toxicon.2020.02.002. Epub 2020 Feb 11. Toxicon. 2020. PMID: 32057833
Rhopalurus junceus is the most common scorpion in Cuba and the venom is often used as a natural product for anti-cancer therapy. ...The current study provides evidence that exposure to low or moderate dose of Rhopalurus junceus scorpion venom by oral r
Rhopalurus junceus is the most common scorpion in Cuba and the venom is often used as a natural product for anti-cancer therap
Enzymatic analysis of venom from Cuban scorpion Rhopalurus junceus.
Díaz-García A, Ruiz-Fuentes JL, Yglesias-Rivera A, Rodríguez-Sánchez H, Riquenes Garlobo Y, Fleitas Martinez O, Fraga Castro JA. Díaz-García A, et al. J Venom Res. 2015 Jul 22;6:11-8. eCollection 2015. J Venom Res. 2015. PMID: 26605039 Free PMC article.
Rhopalurus junceus scorpion venom has been identified as a natural extract with anticancer potential. ...Low molecular weight fractions (<4kDa) induced a significant cytotoxicity in A549 cells while high molecular weight proteins (45-60kDa) were responsible for h
Rhopalurus junceus scorpion venom has been identified as a natural extract with anticancer potential. ...Low molecular weight
The Cuban scorpion Rhopalurus junceus (Scorpiones, Buthidae): component variations in venom samples collected in different geographical areas.
Rodríguez-Ravelo R, Coronas FI, Zamudio FZ, González-Morales L, López GE, Urquiola AR, Possani LD. Rodríguez-Ravelo R, et al. J Venom Anim Toxins Incl Trop Dis. 2013 May 20;19(1):13. doi: 10.1186/1678-9199-19-13. J Venom Anim Toxins Incl Trop Dis. 2013. PMID: 23849540 Free PMC article.
BACKGROUND: The venom of the Cuban scorpion Rhopalurus junceus is poorly study from the point of view of their components at molecular level and the functions associated. ...
BACKGROUND: The venom of the Cuban scorpion Rhopalurus junceus is poorly study from the point of view of their components at m …
Comparative proteomic analysis of male and female venoms from the Cuban scorpion Rhopalurus junceus.
Rodríguez-Ravelo R, Batista CV, Coronas FI, Zamudio FZ, Hernández-Orihuela L, Espinosa-López G, Ruiz-Urquiola A, Possani LD. Rodríguez-Ravelo R, et al. Toxicon. 2015 Dec 1;107(Pt B):327-34. doi: 10.1016/j.toxicon.2015.06.026. Epub 2015 Jul 10. Toxicon. 2015. PMID: 26169670
A complete mass spectrometry analysis of venom components from male and female scorpions of the species Rhophalurus junceus of Cuba is reported. In the order of 200 individual molecular masses were identified in both venoms, from which 63 are identical in male and females …
A complete mass spectrometry analysis of venom components from male and female scorpions of the species Rhophalurus junceus of Cuba i …
Biochemical and molecular characterization of the venom from the Cuban scorpion Rhopalurus junceus.
García-Gómez BI, Coronas FI, Restano-Cassulini R, Rodríguez RR, Possani LD. García-Gómez BI, et al. Toxicon. 2011 Jul;58(1):18-27. doi: 10.1016/j.toxicon.2011.04.011. Epub 2011 May 13. Toxicon. 2011. PMID: 21605585
This communication describes the first general biochemical, molecular and functional characterization of the venom from the Cuban blue scorpion Rhopalurus junceus, which is often used as a natural product for anti-cancer therapy in Cuba. ...
This communication describes the first general biochemical, molecular and functional characterization of the venom from the Cuban blue scorp …
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