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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1962 4
1963 1
1964 1
1974 1
1975 16
1976 21
1977 45
1978 23
1979 25
1980 28
1981 25
1982 31
1983 39
1984 42
1985 56
1986 63
1987 92
1988 83
1989 73
1990 102
1991 72
1992 60
1993 78
1994 73
1995 90
1996 96
1997 89
1998 132
1999 214
2000 282
2001 307
2002 424
2003 512
2004 613
2005 665
2006 661
2007 668
2008 695
2009 781
2010 834
2011 1007
2012 1030
2013 1109
2014 1235
2015 1149
2016 1009
2017 840
2018 689
2019 512
2020 568
2021 436
2022 293
2023 227
2024 194
2025 190
2026 129

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16,986 results

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Page 1
Ribavirin's antiviral mechanism of action: lethal mutagenesis?
Crotty S, Cameron C, Andino R. Crotty S, et al. J Mol Med (Berl). 2002 Feb;80(2):86-95. doi: 10.1007/s00109-001-0308-0. Epub 2001 Dec 4. J Mol Med (Berl). 2002. PMID: 11907645 Review.
Ribavirin, an antiviral drug discovered in 1972, is interesting and important for three reasons: (a) it exhibits antiviral activity against a broad range of RNA viruses; (b) it is currently used clinically to treat hepatitis C virus infections, respiratory sy …
Ribavirin, an antiviral drug discovered in 1972, is interesting and important for three reasons: (a) it exhibits antiviral …
Ribavirin revisited in the era of direct-acting antiviral therapy for hepatitis C virus infection.
Feld JJ, Jacobson IM, Sulkowski MS, Poordad F, Tatsch F, Pawlotsky JM. Feld JJ, et al. Liver Int. 2017 Jan;37(1):5-18. doi: 10.1111/liv.13212. Epub 2016 Sep 29. Liver Int. 2017. PMID: 27473533 Free PMC article. Review.
However, because of treatment-limiting side effects and its additive toxicity with interferon, the search for interferon- and ribavirin-free regimens has been underway. The recent approvals of all-oral direct acting antivirals (DAAs) have revolutionized the HCV ther …
However, because of treatment-limiting side effects and its additive toxicity with interferon, the search for interferon- and ribavirin …
Mechanisms of action of ribavirin in antiviral therapies.
Tam RC, Lau JY, Hong Z. Tam RC, et al. Antivir Chem Chemother. 2001 Sep;12(5):261-72. doi: 10.1177/095632020101200501. Antivir Chem Chemother. 2001. PMID: 11900345 Free article. Review.
First, with emphasis on the evidence for indirect activities of ribavirin, we will review the clinical observations that suggest that the immunomodulatory properties of ribavirin can in part account for its antiviral activities in vivo. We will then describe …
First, with emphasis on the evidence for indirect activities of ribavirin, we will review the clinical observations that suggest that …
Antiviral activity of ribavirin and favipiravir against human astroviruses.
Janowski AB, Dudley H, Wang D. Janowski AB, et al. J Clin Virol. 2020 Feb;123:104247. doi: 10.1016/j.jcv.2019.104247. Epub 2019 Dec 17. J Clin Virol. 2020. PMID: 31864069 Free PMC article.
However, there is a paucity of data regarding the in vitro activity of broad-spectrum RNA antivirals against astroviruses, including ribavirin and favipiravir. OBJECTIVES: We quantified the EC50 values for ribavirin and favipiravir against two human astroviru …
However, there is a paucity of data regarding the in vitro activity of broad-spectrum RNA antivirals against astroviruses, including …
Antiviral activity of Ribavirin nano-particles against measles virus.
Ahmed EM, Solyman SM, Mohamed N, Boseila AA, Hanora A. Ahmed EM, et al. Cell Mol Biol (Noisy-le-grand). 2018 Jun 30;64(9):24-32. Cell Mol Biol (Noisy-le-grand). 2018. PMID: 30030950
Antiviral activiry of ribavirin, AuNPs and ribavirin- AuNPswere determined on vero cells using simultaneous, pre-infection and post-infection protocols. ...Our results concluded that ribavirin - AuNPs had a higher antiviral activity with lower d …
Antiviral activiry of ribavirin, AuNPs and ribavirin- AuNPswere determined on vero cells using simultaneous, pre-infect …
Isosteric ribavirin analogues: Synthesis and antiviral activities.
Zhurilo NI, Chudinov MV, Matveev AV, Smirnova OS, Konstantinova ID, Miroshnikov AI, Prutkov AN, Grebenkina LE, Pulkova NV, Shvets VI. Zhurilo NI, et al. Bioorg Med Chem Lett. 2018 Jan 1;28(1):11-14. doi: 10.1016/j.bmcl.2017.11.029. Epub 2017 Nov 15. Bioorg Med Chem Lett. 2018. PMID: 29173944
The novel isosteric ribavirin analogues were synthesized by two different ways. Some of them showed significant antiviral action against hepatitis C virus (HCV), herpes simplex (HCV-1) and influenza A virus comparable to that of ribavirin itself. The data obt …
The novel isosteric ribavirin analogues were synthesized by two different ways. Some of them showed significant antiviral acti …
Ribavirin Does Not Enhance Hepatitis B Virus Nucleotide Antiviral Activity: A Pilot Study.
Keeshan A, Coffin C, Vachon A, Patel N, Fung S, Mortimer L, Crawley A, Ma M, Osiowy C, Cooper C. Keeshan A, et al. Clin Invest Med. 2022 Dec 31;45(4):E11-15. doi: 10.25011/cim.v45i4.39274. Clin Invest Med. 2022. PMID: 36586101 Clinical Trial.
The use of immune-modulators combined with HBV antivirals is a promising therapeutic strategy to achieve these goals. Based on ribavirin (RBV) monotherapy data, we hypothesized that RBV could improve virological responses when used in combination with tenofovir. .. …
The use of immune-modulators combined with HBV antivirals is a promising therapeutic strategy to achieve these goals. Based on rib …
Chlorination of antiviral drug ribavirin: Kinetics, nontargeted identification, and concomitant toxicity evolution.
Guo K, Liu Y, Peng J, Qi W, Liu H. Guo K, et al. J Hazard Mater. 2024 Apr 5;467:133478. doi: 10.1016/j.jhazmat.2024.133478. Epub 2024 Jan 9. J Hazard Mater. 2024. PMID: 38359766
Residual antiviral drugs in wastewater may increase the risk of generating transformation products (TPs) during wastewater treatment. ...Herein, chlorination kinetics, transformation pathways, and secondary risks of ribavirin (RBV), one of the most commonly used bro …
Residual antiviral drugs in wastewater may increase the risk of generating transformation products (TPs) during wastewater treatment. …
[Ribavirin--pharmacological features, antiviral effects against hepatitis C virus (HCV) and other viruses and side effects during treatment].
Wawrzynowicz-Syczewska M. Wawrzynowicz-Syczewska M. Przegl Epidemiol. 2002;56 Suppl 5:35-40. Przegl Epidemiol. 2002. PMID: 15553070 Review. Polish.
Ribavirin is a broad spectrum antiviral agent first synthesised in 1972. It shows varying degrees of clinical efficacy in a variety of human viral infections including viral hepatitis, respiratory tract infections and haemorrhagic fevers. This review focuses on the …
Ribavirin is a broad spectrum antiviral agent first synthesised in 1972. It shows varying degrees of clinical efficacy in a va …
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