Rice KC - Search Results

1

In vivo evaluation of [123I]-4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(4-iodobenzyl)piperidine, an iodinated SPECT tracer for imaging the P-gp transporter.

De Bruyne S, Wyffels L, Boos TL, Staelens S, Deleye S, Rice KC, De Vos F. De Bruyne S, et al. Among authors: rice kc. Nucl Med Biol. 2010 May;37(4):469-77. doi: 10.1016/j.nucmedbio.2009.10.006. Epub 2010 Apr 7. Nucl Med Biol. 2010. PMID: 20447559

2

Studies of the biogenic amine transporters. XI. Identification of a 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR12909) analog that allosterically modulates the serotonin transporter.

Nightingale B, Dersch CM, Boos TL, Greiner E, Calhoun WJ, Jacobson AE, Rice KC, Rothman RB. Nightingale B, et al. Among authors: rice kc. J Pharmacol Exp Ther. 2005 Aug;314(2):906-15. doi: 10.1124/jpet.105.084376. Epub 2005 Apr 28. J Pharmacol Exp Ther. 2005. PMID: 15860577

3

Structure-activity relationships of substituted N-benzyl piperidines in the GBR series: Synthesis of 4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(2-trifluoromethylbenzyl)piperidine, an allosteric modulator of the serotonin transporter.

Boos TL, Greiner E, Calhoun WJ, Prisinzano TE, Nightingale B, Dersch CM, Rothman RB, Jacobson AE, Rice KC. Boos TL, et al. Among authors: rice kc. Bioorg Med Chem. 2006 Jun 1;14(11):3967-73. doi: 10.1016/j.bmc.2006.01.065. Epub 2006 Mar 24. Bioorg Med Chem. 2006. PMID: 16563775

4

Design and synthesis of promiscuous high-affinity monoamine transporter ligands: unraveling transporter selectivity.

Greiner E, Boos TL, Prisinzano TE, De Martino MG, Zeglis B, Dersch CM, Marcus J, Partilla JS, Rothman RB, Jacobson AE, Rice KC. Greiner E, et al. Among authors: rice kc. J Med Chem. 2006 Mar 9;49(5):1766-72. doi: 10.1021/jm050766f. J Med Chem. 2006. PMID: 16509591

5

DAT/SERT selectivity of flexible GBR 12909 analogs modeled using 3D-QSAR methods.

Gilbert KM, Boos TL, Dersch CM, Greiner E, Jacobson AE, Lewis D, Matecka D, Prisinzano TE, Zhang Y, Rothman RB, Rice KC, Venanzi CA. Gilbert KM, et al. Among authors: rice kc. Bioorg Med Chem. 2007 Jan 15;15(2):1146-59. doi: 10.1016/j.bmc.2006.09.070. Epub 2006 Oct 1. Bioorg Med Chem. 2007. PMID: 17127069 Free PMC article.

6

Reversal of pancreatitis-induced pain by an orally available, small molecule interleukin-6 receptor antagonist.

Vardanyan M, Melemedjian OK, Price TJ, Ossipov MH, Lai J, Roberts E, Boos TL, Deschamps JR, Jacobson AE, Rice KC, Porreca F. Vardanyan M, et al. Among authors: rice kc. Pain. 2010 Nov;151(2):257-265. doi: 10.1016/j.pain.2010.05.022. Epub 2010 Jul 4. Pain. 2010. PMID: 20599324 Free PMC article.

7

3-O-Formyl-20R,21-epoxyresibufogenin suppresses IL-6-type cytokine actions by targeting the glycoprotein 130 subunit: potential clinical implications.

Kino T, Boos TL, Sulima A, Siegel EM, Gold PW, Rice KC, Chrousos GP. Kino T, et al. Among authors: rice kc. J Allergy Clin Immunol. 2007 Aug;120(2):437-44. doi: 10.1016/j.jaci.2007.03.018. Epub 2007 Apr 23. J Allergy Clin Immunol. 2007. PMID: 17451794

8

Configurational reassignment and improved preparation of the competitive IL-6 receptor antagonist 20R,21R-epoxyresibufogenin-3-formate.

Boos TL, Cheng K, Greiner E, Deschamps JR, Jacobson AE, Rice KC. Boos TL, et al. Among authors: rice kc. J Nat Prod. 2012 Apr 27;75(4):661-8. doi: 10.1021/np2008957. Epub 2012 Feb 23. J Nat Prod. 2012. PMID: 22360661 Free PMC article.

9

Piperidine analogues of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR 12909): high affinity ligands for the dopamine transporter.

Prisinzano T, Greiner E, Johnson EM 2nd, Dersch CM, Marcus J, Partilla JS, Rothman RB, Jacobson AE, Rice KC. Prisinzano T, et al. Among authors: rice kc. J Med Chem. 2002 Sep 12;45(19):4371-4. doi: 10.1021/jm020264r. J Med Chem. 2002. PMID: 12213078

10

Structure-activity relationship studies of highly selective inhibitors of the dopamine transporter: N-benzylpiperidine analogues of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine.

Greiner E, Prisinzano T, Johnson EM 2nd, Dersch CM, Marcus J, Partilla JS, Rothman RB, Jacobson AE, Rice KC. Greiner E, et al. Among authors: rice kc. J Med Chem. 2003 Apr 10;46(8):1465-9. doi: 10.1021/jm020419v. J Med Chem. 2003. PMID: 12672246

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