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254 results
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Malignant glioma drug discovery - targeting protein kinases.
Sathornsumetee S, Vredenburgh KA, Lattimore KP, Rich JN. Sathornsumetee S, et al. Among authors: rich jn. Expert Opin Drug Discov. 2007 Jan;2(1):1-17. doi: 10.1517/17460441.2.1.1. Expert Opin Drug Discov. 2007. PMID: 23496034
Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling.
Mack SC, Pajtler KW, Chavez L, Okonechnikov K, Bertrand KC, Wang X, Erkek S, Federation A, Song A, Lee C, Wang X, McDonald L, Morrow JJ, Saiakhova A, Sin-Chan P, Wu Q, Michaelraj KA, Miller TE, Hubert CG, Ryzhova M, Garzia L, Donovan L, Dombrowski S, Factor DC, Luu B, Valentim CLL, Gimple RC, Morton A, Kim L, Prager BC, Lee JJY, Wu X, Zuccaro J, Thompson Y, Holgado BL, Reimand J, Ke SQ, Tropper A, Lai S, Vijayarajah S, Doan S, Mahadev V, Miñan AF, Gröbner SN, Lienhard M, Zapatka M, Huang Z, Aldape KD, Carcaboso AM, Houghton PJ, Keir ST, Milde T, Witt H, Li Y, Li CJ, Bian XW, Jones DTW, Scott I, Singh SK, Huang A, Dirks PB, Bouffet E, Bradner JE, Ramaswamy V, Jabado N, Rutka JT, Northcott PA, Lupien M, Lichter P, Korshunov A, Scacheri PC, Pfister SM, Kool M, Taylor MD, Rich JN. Mack SC, et al. Among authors: rich jn. Nature. 2018 Jan 4;553(7686):101-105. doi: 10.1038/nature25169. Epub 2017 Dec 20. Nature. 2018. PMID: 29258295 Free PMC article.
Challenges to curing primary brain tumours.
Aldape K, Brindle KM, Chesler L, Chopra R, Gajjar A, Gilbert MR, Gottardo N, Gutmann DH, Hargrave D, Holland EC, Jones DTW, Joyce JA, Kearns P, Kieran MW, Mellinghoff IK, Merchant M, Pfister SM, Pollard SM, Ramaswamy V, Rich JN, Robinson GW, Rowitch DH, Sampson JH, Taylor MD, Workman P, Gilbertson RJ. Aldape K, et al. Among authors: rich jn. Nat Rev Clin Oncol. 2019 Aug;16(8):509-520. doi: 10.1038/s41571-019-0177-5. Nat Rev Clin Oncol. 2019. PMID: 30733593 Free PMC article. Review.
Phase II study of Cloretazine for the treatment of adults with recurrent glioblastoma multiforme.
Badruddoja MA, Penne K, Desjardins A, Reardon DA, Rich JN, Quinn JA, Sathornsumetee S, Friedman AH, Bigner DD, Herndon JE 2nd, Cahill A, Friedman HS, Vredenburgh JJ. Badruddoja MA, et al. Among authors: rich jn. Neuro Oncol. 2007 Jan;9(1):70-4. doi: 10.1215/15228517-2006-022. Epub 2006 Nov 15. Neuro Oncol. 2007. PMID: 17108065 Free PMC article. Clinical Trial.
Phase I trial of irinotecan plus temozolomide in adults with recurrent malignant glioma.
Reardon DA, Quinn JA, Rich JN, Desjardins A, Vredenburgh J, Gururangan S, Sathornsumetee S, Badruddoja M, McLendon R, Provenzale J, Herndon JE 2nd, Dowell JM, Burkart JL, Newton HB, Friedman AH, Friedman HS. Reardon DA, et al. Among authors: rich jn. Cancer. 2005 Oct 1;104(7):1478-86. doi: 10.1002/cncr.21316. Cancer. 2005. PMID: 16088964 Clinical Trial.
Phase I study of sunitinib and irinotecan for patients with recurrent malignant glioma.
Reardon DA, Vredenburgh JJ, Coan A, Desjardins A, Peters KB, Gururangan S, Sathornsumetee S, Rich JN, Herndon JE, Friedman HS. Reardon DA, et al. Among authors: rich jn. J Neurooncol. 2011 Dec;105(3):621-7. doi: 10.1007/s11060-011-0631-4. Epub 2011 Jul 9. J Neurooncol. 2011. PMID: 21744079 Free PMC article. Clinical Trial.
Phase II trial of bevacizumab and erlotinib in patients with recurrent malignant glioma.
Sathornsumetee S, Desjardins A, Vredenburgh JJ, McLendon RE, Marcello J, Herndon JE, Mathe A, Hamilton M, Rich JN, Norfleet JA, Gururangan S, Friedman HS, Reardon DA. Sathornsumetee S, et al. Among authors: rich jn. Neuro Oncol. 2010 Dec;12(12):1300-10. doi: 10.1093/neuonc/noq099. Epub 2010 Aug 17. Neuro Oncol. 2010. PMID: 20716591 Free PMC article. Clinical Trial.
Targeting interleukin 6 signaling suppresses glioma stem cell survival and tumor growth.
Wang H, Lathia JD, Wu Q, Wang J, Li Z, Heddleston JM, Eyler CE, Elderbroom J, Gallagher J, Schuschu J, MacSwords J, Cao Y, McLendon RE, Wang XF, Hjelmeland AB, Rich JN. Wang H, et al. Among authors: rich jn. Stem Cells. 2009 Oct;27(10):2393-404. doi: 10.1002/stem.188. Stem Cells. 2009. PMID: 19658188 Free PMC article.
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