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De novo protein design enables the precise induction of RSV-neutralizing antibodies.
Sesterhenn F, Yang C, Bonet J, Cramer JT, Wen X, Wang Y, Chiang CI, Abriata LA, Kucharska I, Castoro G, Vollers SS, Galloux M, Dheilly E, Rosset S, Corthésy P, Georgeon S, Villard M, Richard CA, Descamps D, Delgado T, Oricchio E, Rameix-Welti MA, Más V, Ervin S, Eléouët JF, Riffault S, Bates JT, Julien JP, Li Y, Jardetzky T, Krey T, Correia BE. Sesterhenn F, et al. Among authors: richard ca. Science. 2020 May 15;368(6492):eaay5051. doi: 10.1126/science.aay5051. Science. 2020. PMID: 32409444 Free PMC article.
Crystal structure of the essential transcription antiterminator M2-1 protein of human respiratory syncytial virus and implications of its phosphorylation.
Tanner SJ, Ariza A, Richard CA, Kyle HF, Dods RL, Blondot ML, Wu W, Trincão J, Trinh CH, Hiscox JA, Carroll MW, Silman NJ, Eléouët JF, Edwards TA, Barr JN. Tanner SJ, et al. Among authors: richard ca. Proc Natl Acad Sci U S A. 2014 Jan 28;111(4):1580-5. doi: 10.1073/pnas.1317262111. Epub 2014 Jan 13. Proc Natl Acad Sci U S A. 2014. PMID: 24434552 Free PMC article.
The Structure of the Human Respiratory Syncytial Virus M2-1 Protein Bound to the Interaction Domain of the Phosphoprotein P Defines the Orientation of the Complex.
Selvaraj M, Yegambaram K, Todd EJAA, Richard CA, Dods RL, Pangratiou GM, Trinh CH, Moul SL, Murphy JC, Mankouri J, Éléouët JF, Barr JN, Edwards TA. Selvaraj M, et al. Among authors: richard ca. mBio. 2018 Nov 13;9(6):e01554-18. doi: 10.1128/mBio.01554-18. mBio. 2018. PMID: 30425144 Free PMC article.
Targeting the Respiratory Syncytial Virus N0-P Complex with Constrained α-Helical Peptides in Cells and Mice.
Galloux M, Gsponer N, Gaillard V, Fenner B, Larcher T, Vilotte M, Rivière J, Richard CA, Eléouët JF, Le Goffic R, Mettier J, Nyanguile O. Galloux M, et al. Among authors: richard ca. Antimicrob Agents Chemother. 2020 Sep 21;64(10):e00717-20. doi: 10.1128/AAC.00717-20. Print 2020 Sep 21. Antimicrob Agents Chemother. 2020. PMID: 32660994 Free PMC article.
146 results