Richards FM - Search Results

1

Design, synthesis, and biological evaluation of an allosteric inhibitor of HSET that targets cancer cells with supernumerary centrosomes.

Watts CA, Richards FM, Bender A, Bond PJ, Korb O, Kern O, Riddick M, Owen P, Myers RM, Raff J, Gergely F, Jodrell DI, Ley SV. Watts CA, et al. Among authors: richards fm. Chem Biol. 2013 Nov 21;20(11):1399-410. doi: 10.1016/j.chembiol.2013.09.012. Epub 2013 Oct 24. Chem Biol. 2013. PMID: 24210220 Free PMC article.

2

A novel method for quantification of gemcitabine and its metabolites 2',2'-difluorodeoxyuridine and gemcitabine triphosphate in tumour tissue by LC-MS/MS: comparison with (19)F NMR spectroscopy.

Bapiro TE, Richards FM, Goldgraben MA, Olive KP, Madhu B, Frese KK, Cook N, Jacobetz MA, Smith DM, Tuveson DA, Griffiths JR, Jodrell DI. Bapiro TE, et al. Among authors: richards fm. Cancer Chemother Pharmacol. 2011 Nov;68(5):1243-53. doi: 10.1007/s00280-011-1613-0. Epub 2011 Mar 23. Cancer Chemother Pharmacol. 2011. PMID: 21431415 Free PMC article.

3

Anti-tumour effects of a specific anti-ADAM17 antibody in an ovarian cancer model in vivo.

Richards FM, Tape CJ, Jodrell DI, Murphy G. Richards FM, et al. PLoS One. 2012;7(7):e40597. doi: 10.1371/journal.pone.0040597. Epub 2012 Jul 11. PLoS One. 2012. PMID: 22792380 Free PMC article.

4

Paclitaxel and CYC3, an aurora kinase A inhibitor, synergise in pancreatic cancer cells but not bone marrow precursor cells.

Lin Y, Richards FM, Krippendorff BF, Bramhall JL, Harrington JA, Bapiro TE, Robertson A, Zheleva D, Jodrell DI. Lin Y, et al. Among authors: richards fm. Br J Cancer. 2012 Nov 6;107(10):1692-701. doi: 10.1038/bjc.2012.450. Epub 2012 Oct 4. Br J Cancer. 2012. PMID: 23037716 Free PMC article.

5

Anti-tumour efficacy of capecitabine in a genetically engineered mouse model of pancreatic cancer.

Courtin A, Richards FM, Bapiro TE, Bramhall JL, Neesse A, Cook N, Krippendorff BF, Tuveson DA, Jodrell DI. Courtin A, et al. Among authors: richards fm. PLoS One. 2013 Jun 28;8(6):e67330. doi: 10.1371/journal.pone.0067330. Print 2013. PLoS One. 2013. PMID: 23840665 Free PMC article.

6

SPARC independent drug delivery and antitumour effects of nab-paclitaxel in genetically engineered mice.

Neesse A, Frese KK, Chan DS, Bapiro TE, Howat WJ, Richards FM, Ellenrieder V, Jodrell DI, Tuveson DA. Neesse A, et al. Among authors: richards fm. Gut. 2014 Jun;63(6):974-83. doi: 10.1136/gutjnl-2013-305559. Epub 2013 Sep 25. Gut. 2014. PMID: 24067278 Free PMC article.

7

Gemcitabine diphosphate choline is a major metabolite linked to the Kennedy pathway in pancreatic cancer models in vivo.

Bapiro TE, Frese KK, Courtin A, Bramhall JL, Madhu B, Cook N, Neesse A, Griffiths JR, Tuveson DA, Jodrell DI, Richards FM. Bapiro TE, et al. Among authors: richards fm. Br J Cancer. 2014 Jul 15;111(2):318-25. doi: 10.1038/bjc.2014.288. Epub 2014 May 29. Br J Cancer. 2014. PMID: 24874484 Free PMC article.

8

The EGFR demonstrates linear signal transmission.

Oyarzún DA, Bramhall JL, López-Caamal F, Richards FM, Jodrell DI, Krippendorff BF. Oyarzún DA, et al. Among authors: richards fm. Integr Biol (Camb). 2014 Aug;6(8):736-42. doi: 10.1039/c4ib00062e. Integr Biol (Camb). 2014. PMID: 24934872

9

CHK1 Inhibition Synergizes with Gemcitabine Initially by Destabilizing the DNA Replication Apparatus.

Koh SB, Courtin A, Boyce RJ, Boyle RG, Richards FM, Jodrell DI. Koh SB, et al. Among authors: richards fm. Cancer Res. 2015 Sep 1;75(17):3583-95. doi: 10.1158/0008-5472.CAN-14-3347. Epub 2015 Jul 3. Cancer Res. 2015. PMID: 26141863

10

An automated fitting procedure and software for dose-response curves with multiphasic features.

Di Veroli GY, Fornari C, Goldlust I, Mills G, Koh SB, Bramhall JL, Richards FM, Jodrell DI. Di Veroli GY, et al. Among authors: richards fm. Sci Rep. 2015 Oct 1;5:14701. doi: 10.1038/srep14701. Sci Rep. 2015. PMID: 26424192 Free PMC article.

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