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Non-cognitive behaviours in an APP/PS1 transgenic model of Alzheimer's disease.
Pugh PL, Richardson JC, Bate ST, Upton N, Sunter D. Pugh PL, et al. Among authors: richardson jc. Behav Brain Res. 2007 Mar 12;178(1):18-28. doi: 10.1016/j.bbr.2006.11.044. Epub 2007 Jan 16. Behav Brain Res. 2007. PMID: 17229472
Ultrastructural and behavioural changes precede amyloid deposition in a transgenic model of Alzheimer's disease.
Richardson JC, Kendal CE, Anderson R, Priest F, Gower E, Soden P, Gray R, Topps S, Howlett DR, Lavender D, Clarke NJ, Barnes JC, Haworth R, Stewart MG, Rupniak HT. Richardson JC, et al. Neuroscience. 2003;122(1):213-28. doi: 10.1016/s0306-4522(03)00389-0. Neuroscience. 2003. PMID: 14596862
Cognitive correlates of Abeta deposition in male and female mice bearing amyloid precursor protein and presenilin-1 mutant transgenes.
Howlett DR, Richardson JC, Austin A, Parsons AA, Bate ST, Davies DC, Gonzalez MI. Howlett DR, et al. Among authors: richardson jc. Brain Res. 2004 Aug 13;1017(1-2):130-6. doi: 10.1016/j.brainres.2004.05.029. Brain Res. 2004. PMID: 15261108
Synaptic transmission and synchronous activity is disrupted in hippocampal slices taken from aged TAS10 mice.
Brown JT, Richardson JC, Collingridge GL, Randall AD, Davies CH. Brown JT, et al. Among authors: richardson jc. Hippocampus. 2005;15(1):110-7. doi: 10.1002/hipo.20036. Hippocampus. 2005. PMID: 15390159
Modulation of hippocampal excitability by 5-HT4 receptor agonists persists in a transgenic model of Alzheimer's disease.
Spencer JP, Brown JT, Richardson JC, Medhurst AD, Sehmi SS, Calver AR, Randall AD. Spencer JP, et al. Among authors: richardson jc. Neuroscience. 2004;129(1):49-54. doi: 10.1016/j.neuroscience.2004.06.070. Neuroscience. 2004. PMID: 15489027
Fibre diffraction of hair can provide a screening test for Alzheimer's disease: a human and animal model study.
James VJ, Richardson JC, Robertson TA, Papadimitriou JM, Dutton NS, Maley MA, Berstein LM, Lantseva OE, Martins RN. James VJ, et al. Among authors: richardson jc. Med Sci Monit. 2005 Feb;11(2):CR53-7. Med Sci Monit. 2005. PMID: 15668631
Transgenic mice over-expressing human beta-amyloid have functional nicotinic alpha 7 receptors.
Spencer JP, Weil A, Hill K, Hussain I, Richardson JC, Cusdin FS, Chen YH, Randall AD. Spencer JP, et al. Among authors: richardson jc. Neuroscience. 2006 Feb;137(3):795-805. doi: 10.1016/j.neuroscience.2005.10.007. Epub 2005 Nov 21. Neuroscience. 2006. PMID: 16303255
MAPK-activated protein kinase 2 deficiency in microglia inhibits pro-inflammatory mediator release and resultant neurotoxicity. Relevance to neuroinflammation in a transgenic mouse model of Alzheimer disease.
Culbert AA, Skaper SD, Howlett DR, Evans NA, Facci L, Soden PE, Seymour ZM, Guillot F, Gaestel M, Richardson JC. Culbert AA, et al. Among authors: richardson jc. J Biol Chem. 2006 Aug 18;281(33):23658-67. doi: 10.1074/jbc.M513646200. Epub 2006 Jun 14. J Biol Chem. 2006. PMID: 16774924
Repeated administration of the noradrenergic neurotoxin N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4) modulates neuroinflammation and amyloid plaque load in mice bearing amyloid precursor protein and presenilin-1 mutant transgenes.
Pugh PL, Vidgeon-Hart MP, Ashmeade T, Culbert AA, Seymour Z, Perren MJ, Joyce F, Bate ST, Babin A, Virley DJ, Richardson JC, Upton N, Sunter D. Pugh PL, et al. Among authors: richardson jc. J Neuroinflammation. 2007 Feb 26;4:8. doi: 10.1186/1742-2094-4-8. J Neuroinflammation. 2007. PMID: 17324270 Free PMC article.
Collapsin response mediator protein-2 hyperphosphorylation is an early event in Alzheimer's disease progression.
Cole AR, Noble W, van Aalten L, Plattner F, Meimaridou R, Hogan D, Taylor M, LaFrancois J, Gunn-Moore F, Verkhratsky A, Oddo S, LaFerla F, Giese KP, Dineley KT, Duff K, Richardson JC, Yan SD, Hanger DP, Allan SM, Sutherland C. Cole AR, et al. Among authors: richardson jc. J Neurochem. 2007 Nov;103(3):1132-44. doi: 10.1111/j.1471-4159.2007.04829.x. Epub 2007 Aug 7. J Neurochem. 2007. PMID: 17683481
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