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Neuropeptide S receptor gene -- converging evidence for a role in panic disorder.
Domschke K, Reif A, Weber H, Richter J, Hohoff C, Ohrmann P, Pedersen A, Bauer J, Suslow T, Kugel H, Heindel W, Baumann C, Klauke B, Jacob C, Maier W, Fritze J, Bandelow B, Krakowitzky P, Rothermundt M, Erhardt A, Binder EB, Holsboer F, Gerlach AL, Kircher T, Lang T, Alpers GW, Ströhle A, Fehm L, Gloster AT, Wittchen HU, Arolt V, Pauli P, Hamm A, Deckert J. Domschke K, et al. Mol Psychiatry. 2011 Sep;16(9):938-48. doi: 10.1038/mp.2010.81. Epub 2010 Jul 6. Mol Psychiatry. 2011. PMID: 20603625
GLRB allelic variation associated with agoraphobic cognitions, increased startle response and fear network activation: a potential neurogenetic pathway to panic disorder.
Deckert J, Weber H, Villmann C, Lonsdorf TB, Richter J, Andreatta M, Arias-Vasquez A, Hommers L, Kent L, Schartner C, Cichon S, Wolf C, Schaefer N, von Collenberg CR, Wachter B, Blum R, Schümann D, Scharfenort R, Schumacher J, Forstner AJ, Baumann C, Schiele MA, Notzon S, Zwanzger P, Janzing JGE, Galesloot T, Kiemeney LA, Gajewska A, Glotzbach-Schoon E, Mühlberger A, Alpers G, Fydrich T, Fehm L, Gerlach AL, Kircher T, Lang T, Ströhle A, Arolt V, Wittchen HU, Kalisch R, Büchel C, Hamm A, Nöthen MM, Romanos M, Domschke K, Pauli P, Reif A. Deckert J, et al. Mol Psychiatry. 2017 Oct;22(10):1431-1439. doi: 10.1038/mp.2017.2. Epub 2017 Feb 7. Mol Psychiatry. 2017. PMID: 28167838
MAOA and mechanisms of panic disorder revisited: from bench to molecular psychotherapy.
Reif A, Richter J, Straube B, Höfler M, Lueken U, Gloster AT, Weber H, Domschke K, Fehm L, Ströhle A, Jansen A, Gerlach A, Pyka M, Reinhardt I, Konrad C, Wittmann A, Pfleiderer B, Alpers GW, Pauli P, Lang T, Arolt V, Wittchen HU, Hamm A, Kircher T, Deckert J. Reif A, et al. Mol Psychiatry. 2014 Jan;19(1):122-8. doi: 10.1038/mp.2012.172. Epub 2013 Jan 15. Mol Psychiatry. 2014. PMID: 23319006 Clinical Trial.
Allelic variation in CRHR1 predisposes to panic disorder: evidence for biased fear processing.
Weber H, Richter J, Straube B, Lueken U, Domschke K, Schartner C, Klauke B, Baumann C, Pané-Farré C, Jacob CP, Scholz CJ, Zwanzger P, Lang T, Fehm L, Jansen A, Konrad C, Fydrich T, Wittmann A, Pfleiderer B, Ströhle A, Gerlach AL, Alpers GW, Arolt V, Pauli P, Wittchen HU, Kent L, Hamm A, Kircher T, Deckert J, Reif A. Weber H, et al. Mol Psychiatry. 2016 Jun;21(6):813-22. doi: 10.1038/mp.2015.125. Epub 2015 Sep 1. Mol Psychiatry. 2016. PMID: 26324098
Dimensional structure of bodily panic attack symptoms and their specific connections to panic cognitions, anxiety sensitivity and claustrophobic fears.
Drenckhan I, Glöckner-Rist A, Rist F, Richter J, Gloster AT, Fehm L, Lang T, Alpers GW, Hamm AO, Fydrich T, Kircher T, Arolt V, Deckert J, Ströhle A, Wittchen HU, Gerlach AL. Drenckhan I, et al. Psychol Med. 2015 Jun;45(8):1675-85. doi: 10.1017/S0033291714002803. Epub 2014 Dec 8. Psychol Med. 2015. PMID: 25482960
Mechanism of action in CBT (MAC): methods of a multi-center randomized controlled trial in 369 patients with panic disorder and agoraphobia.
Gloster AT, Wittchen HU, Einsle F, Höfler M, Lang T, Helbig-Lang S, Fydrich T, Fehm L, Hamm AO, Richter J, Alpers GW, Gerlach AL, Ströhle A, Kircher T, Deckert J, Zwanzger P, Arolt V. Gloster AT, et al. Eur Arch Psychiatry Clin Neurosci. 2009 Nov;259 Suppl 2:S155-66. doi: 10.1007/s00406-009-0065-6. Eur Arch Psychiatry Clin Neurosci. 2009. PMID: 19876674 Clinical Trial.
A functional genetic variation of SLC6A2 repressor hsa-miR-579-3p upregulates sympathetic noradrenergic processes of fear and anxiety.
Hommers LG, Richter J, Yang Y, Raab A, Baumann C, Lang K, Schiele MA, Weber H, Wittmann A, Wolf C, Alpers GW, Arolt V, Domschke K, Fehm L, Fydrich T, Gerlach A, Gloster AT, Hamm AO, Helbig-Lang S, Kircher T, Lang T, Pané-Farré CA, Pauli P, Pfleiderer B, Reif A, Romanos M, Straube B, Ströhle A, Wittchen HU, Frantz S, Ertl G, Lohse MJ, Lueken U, Deckert J. Hommers LG, et al. Transl Psychiatry. 2018 Oct 19;8(1):226. doi: 10.1038/s41398-018-0278-4. Transl Psychiatry. 2018. PMID: 30341278 Free PMC article.
MAOA gene hypomethylation in panic disorder-reversibility of an epigenetic risk pattern by psychotherapy.
Ziegler C, Richter J, Mahr M, Gajewska A, Schiele MA, Gehrmann A, Schmidt B, Lesch KP, Lang T, Helbig-Lang S, Pauli P, Kircher T, Reif A, Rief W, Vossbeck-Elsebusch AN, Arolt V, Wittchen HU, Hamm AO, Deckert J, Domschke K. Ziegler C, et al. Transl Psychiatry. 2016 Apr 5;6(4):e773. doi: 10.1038/tp.2016.41. Transl Psychiatry. 2016. PMID: 27045843 Free PMC article.
34 results