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Page 1
Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities.
Menzies FM, Fleming A, Caricasole A, Bento CF, Andrews SP, Ashkenazi A, Füllgrabe J, Jackson A, Jimenez Sanchez M, Karabiyik C, Licitra F, Lopez Ramirez A, Pavel M, Puri C, Renna M, Ricketts T, Schlotawa L, Vicinanza M, Won H, Zhu Y, Skidmore J, Rubinsztein DC. Menzies FM, et al. Among authors: ricketts t. Neuron. 2017 Mar 8;93(5):1015-1034. doi: 10.1016/j.neuron.2017.01.022. Neuron. 2017. PMID: 28279350 Free article. Review.
Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing.
Siddiqi FH, Menzies FM, Lopez A, Stamatakou E, Karabiyik C, Ureshino R, Ricketts T, Jimenez-Sanchez M, Esteban MA, Lai L, Tortorella MD, Luo Z, Liu H, Metzakopian E, Fernandes HJR, Bassett A, Karran E, Miller BL, Fleming A, Rubinsztein DC. Siddiqi FH, et al. Among authors: ricketts t. Nat Commun. 2019 Apr 18;10(1):1817. doi: 10.1038/s41467-019-09494-2. Nat Commun. 2019. PMID: 31000720 Free PMC article.
Autophagy and neurodegeneration.
Frake RA, Ricketts T, Menzies FM, Rubinsztein DC. Frake RA, et al. Among authors: ricketts t. J Clin Invest. 2015 Jan;125(1):65-74. doi: 10.1172/JCI73944. Epub 2015 Jan 2. J Clin Invest. 2015. PMID: 25654552 Free PMC article. Review.
Polyglutamine tracts regulate beclin 1-dependent autophagy.
Ashkenazi A, Bento CF, Ricketts T, Vicinanza M, Siddiqi F, Pavel M, Squitieri F, Hardenberg MC, Imarisio S, Menzies FM, Rubinsztein DC. Ashkenazi A, et al. Among authors: ricketts t. Nature. 2017 May 4;545(7652):108-111. doi: 10.1038/nature22078. Epub 2017 Apr 26. Nature. 2017. PMID: 28445460 Free PMC article.
Polyglutamine tracts regulate autophagy.
Ashkenazi A, Bento CF, Ricketts T, Vicinanza M, Siddiqi F, Pavel M, Squitieri F, Hardenberg MC, Imarisio S, Menzies FM, Rubinsztein DC. Ashkenazi A, et al. Among authors: ricketts t. Autophagy. 2017 Sep 2;13(9):1613-1614. doi: 10.1080/15548627.2017.1336278. Epub 2017 Jul 19. Autophagy. 2017. PMID: 28722507 Free PMC article.
Calpain inhibition mediates autophagy-dependent protection against polyglutamine toxicity.
Menzies FM, Garcia-Arencibia M, Imarisio S, O'Sullivan NC, Ricketts T, Kent BA, Rao MV, Lam W, Green-Thompson ZW, Nixon RA, Saksida LM, Bussey TJ, O'Kane CJ, Rubinsztein DC. Menzies FM, et al. Among authors: ricketts t. Cell Death Differ. 2015 Mar;22(3):433-44. doi: 10.1038/cdd.2014.151. Epub 2014 Sep 26. Cell Death Differ. 2015. PMID: 25257175 Free PMC article.
Author Correction: Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing.
Siddiqi FH, Menzies FM, Lopez A, Stamatakou E, Karabiyik C, Ureshino R, Ricketts T, Jimenez-Sanchez M, Esteban MA, Lai L, Tortorella MD, Luo Z, Liu H, Metzakopian E, Fernandes HJR, Bassett A, Karran E, Miller BL, Fleming A, Rubinsztein DC. Siddiqi FH, et al. Among authors: ricketts t. Nat Commun. 2019 Jun 4;10(1):2530. doi: 10.1038/s41467-019-10536-y. Nat Commun. 2019. PMID: 31164655 Free PMC article.
426 results