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The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation.
Ricote M, Li AC, Willson TM, Kelly CJ, Glass CK. Ricote M, et al. Nature. 1998 Jan 1;391(6662):79-82. doi: 10.1038/34178. Nature. 1998. PMID: 9422508
Retinoid X receptor α attenuates host antiviral response by suppressing type I interferon.
Ma F, Liu SY, Razani B, Arora N, Li B, Kagechika H, Tontonoz P, Núñez V, Ricote M, Cheng G. Ma F, et al. Among authors: ricote m. Nat Commun. 2014 Nov 24;5:5494. doi: 10.1038/ncomms6494. Nat Commun. 2014. PMID: 25417649 Free PMC article.
MT4-MMP deficiency increases patrolling monocyte recruitment to early lesions and accelerates atherosclerosis.
Clemente C, Rius C, Alonso-Herranz L, Martín-Alonso M, Pollán Á, Camafeita E, Martínez F, Mota RA, Núñez V, Rodríguez C, Seiki M, Martínez-González J, Andrés V, Ricote M, Arroyo AG. Clemente C, et al. Among authors: ricote m. Nat Commun. 2018 Mar 2;9(1):910. doi: 10.1038/s41467-018-03351-4. Nat Commun. 2018. PMID: 29500407 Free PMC article.
Macrophage peroxisome proliferator activated receptor gamma as a therapeutic target to combat Type 2 diabetes.
Pascual G, Ricote M, Hevener AL. Pascual G, et al. Among authors: ricote m. Expert Opin Ther Targets. 2007 Nov;11(11):1503-20. doi: 10.1517/14728222.11.11.1503. Expert Opin Ther Targets. 2007. PMID: 18028013 Review.
Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones.
Hevener AL, Olefsky JM, Reichart D, Nguyen MT, Bandyopadyhay G, Leung HY, Watt MJ, Benner C, Febbraio MA, Nguyen AK, Folian B, Subramaniam S, Gonzalez FJ, Glass CK, Ricote M. Hevener AL, et al. Among authors: ricote m. J Clin Invest. 2007 Jun;117(6):1658-69. doi: 10.1172/JCI31561. Epub 2007 May 24. J Clin Invest. 2007. PMID: 17525798 Free PMC article.
Repression of IFN-gamma expression by peroxisome proliferator-activated receptor gamma.
Cunard R, Eto Y, Muljadi JT, Glass CK, Kelly CJ, Ricote M. Cunard R, et al. Among authors: ricote m. J Immunol. 2004 Jun 15;172(12):7530-6. doi: 10.4049/jimmunol.172.12.7530. J Immunol. 2004. PMID: 15187132
Nuclear receptor signaling in macrophages.
Valledor AF, Ricote M. Valledor AF, et al. Among authors: ricote m. Biochem Pharmacol. 2004 Jan 15;67(2):201-12. doi: 10.1016/j.bcp.2003.10.016. Biochem Pharmacol. 2004. PMID: 14698033 Review.
Decoding transcriptional programs regulated by PPARs and LXRs in the macrophage: effects on lipid homeostasis, inflammation, and atherosclerosis.
Ricote M, Valledor AF, Glass CK. Ricote M, et al. Arterioscler Thromb Vasc Biol. 2004 Feb;24(2):230-9. doi: 10.1161/01.ATV.0000103951.67680.B1. Epub 2003 Oct 30. Arterioscler Thromb Vasc Biol. 2004. PMID: 14592855 Review.
WY14,643, a PPAR alpha ligand, has profound effects on immune responses in vivo.
Cunard R, DiCampli D, Archer DC, Stevenson JL, Ricote M, Glass CK, Kelly CJ. Cunard R, et al. Among authors: ricote m. J Immunol. 2002 Dec 15;169(12):6806-12. doi: 10.4049/jimmunol.169.12.6806. J Immunol. 2002. PMID: 12471112
PPARgamma and PPARdelta negatively regulate specific subsets of lipopolysaccharide and IFN-gamma target genes in macrophages.
Welch JS, Ricote M, Akiyama TE, Gonzalez FJ, Glass CK. Welch JS, et al. Among authors: ricote m. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6712-7. doi: 10.1073/pnas.1031789100. Epub 2003 May 9. Proc Natl Acad Sci U S A. 2003. PMID: 12740443 Free PMC article.
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