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Tp53-induced glycolysis and apoptosis regulator (TIGAR) protects glioma cells from starvation-induced cell death by up-regulating respiration and improving cellular redox homeostasis.
Wanka C, Steinbach JP, Rieger J. Wanka C, et al. J Biol Chem. 2012 Sep 28;287(40):33436-46. doi: 10.1074/jbc.M112.384578. Epub 2012 Aug 10. J Biol Chem. 2012. PMID: 22887998 Free PMC article.
Disruption of peroxisome proliferator-activated receptor γ coactivator (PGC)-1α reverts key features of the neoplastic phenotype of glioma cells.
Bruns I, Sauer B, Burger MC, Eriksson J, Hofmann U, Braun Y, Harter PN, Luger AL, Ronellenfitsch MW, Steinbach JP, Rieger J. Bruns I, et al. J Biol Chem. 2019 Mar 1;294(9):3037-3050. doi: 10.1074/jbc.RA118.006993. Epub 2018 Dec 21. J Biol Chem. 2019. PMID: 30578297 Free PMC article.
BCL-2 family proteins modulate radiosensitivity in human malignant glioma cells.
Streffer JR, Rimner A, Rieger J, Naumann U, Rodemann HP, Weller M. Streffer JR, et al. J Neurooncol. 2002 Jan;56(1):43-9. doi: 10.1023/a:1014448721327. J Neurooncol. 2002. PMID: 11949826
Antagonism of the mammalian target of rapamycin selectively mediates metabolic effects of epidermal growth factor receptor inhibition and protects human malignant glioma cells from hypoxia-induced cell death.
Ronellenfitsch MW, Brucker DP, Burger MC, Wolking S, Tritschler F, Rieger J, Wick W, Weller M, Steinbach JP. Ronellenfitsch MW, et al. Brain. 2009 Jun;132(Pt 6):1509-22. doi: 10.1093/brain/awp093. Epub 2009 May 4. Brain. 2009. PMID: 19416948
Bevacizumab-induced diffusion-restricted lesions in malignant glioma patients.
Rieger J, Bähr O, Müller K, Franz K, Steinbach J, Hattingen E. Rieger J, et al. J Neurooncol. 2010 Aug;99(1):49-56. doi: 10.1007/s11060-009-0098-8. Epub 2009 Dec 25. J Neurooncol. 2010. PMID: 20035366
Confounding factors in diagnostics of MGMT promoter methylation status in glioblastomas in stereotactic biopsies.
Weise LM, Harter PN, Eibach S, Braczynski AK, Dunst M, Rieger J, Bähr O, Hattingen E, Steinbach JP, Plate KH, Seifert V, Mittelbronn M. Weise LM, et al. Stereotact Funct Neurosurg. 2014;92(3):129-39. doi: 10.1159/000360582. Epub 2014 Apr 24. Stereotact Funct Neurosurg. 2014. PMID: 24776650
Suppression of oxidative phosphorylation confers resistance against bevacizumab in experimental glioma.
Eriksson JA, Wanka C, Burger MC, Urban H, Hartel I, von Renesse J, Harter PN, Mittelbronn M, Steinbach JP, Rieger J. Eriksson JA, et al. J Neurochem. 2018 Feb;144(4):421-430. doi: 10.1111/jnc.14264. Epub 2018 Jan 8. J Neurochem. 2018. PMID: 29178334
Activation of AMP-activated kinase modulates sensitivity of glioma cells against epidermal growth factor receptor inhibition.
Hartel I, Ronellenfitsch M, Wanka C, Wolking S, Steinbach JP, Rieger J. Hartel I, et al. Int J Oncol. 2016 Jul;49(1):173-80. doi: 10.3892/ijo.2016.3498. Epub 2016 Apr 25. Int J Oncol. 2016. PMID: 27121290
Perioperative cerebral ischemia promote infiltrative recurrence in glioblastoma.
Thiepold AL, Luger S, Wagner M, Filmann N, Ronellenfitsch MW, Harter PN, Braczynski AK, Dützmann S, Hattingen E, Steinbach JP, Senft C, Rieger J, Bähr O. Thiepold AL, et al. Oncotarget. 2015 Jun 10;6(16):14537-44. doi: 10.18632/oncotarget.3994. Oncotarget. 2015. PMID: 25966341 Free PMC article.
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