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Increased sensitivity to apoptosis upon endoplasmic reticulum stress-induced activation of the unfolded protein response in chemotherapy-resistant malignant pleural mesothelioma.
Xu D, Liang SQ, Yang H, Lüthi U, Riether C, Berezowska S, Marti TM, Hall SRR, Bruggmann R, Kocher GJ, Schmid RA, Peng RW. Xu D, et al. Among authors: riether c. Br J Cancer. 2018 Jul;119(1):65-75. doi: 10.1038/s41416-018-0145-3. Epub 2018 Jun 20. Br J Cancer. 2018. PMID: 29921948 Free PMC article.
mTOR mediates a mechanism of resistance to chemotherapy and defines a rational combination strategy to treat KRAS-mutant lung cancer.
Liang SQ, Bührer ED, Berezowska S, Marti TM, Xu D, Froment L, Yang H, Hall SRR, Vassella E, Yang Z, Kocher GJ, Amrein MA, Riether C, Ochsenbein AF, Schmid RA, Peng RW. Liang SQ, et al. Among authors: riether c. Oncogene. 2019 Jan;38(5):622-636. doi: 10.1038/s41388-018-0479-6. Epub 2018 Aug 31. Oncogene. 2019. PMID: 30171261
Tumor Initiation Capacity and Therapy Resistance Are Differential Features of EMT-Related Subpopulations in the NSCLC Cell Line A549.
Tièche CC, Gao Y, Bührer ED, Hobi N, Berezowska SA, Wyler K, Froment L, Weis S, Peng RW, Bruggmann R, Schär P, Amrein MA, Hall SRR, Dorn P, Kocher G, Riether C, Ochsenbein A, Schmid RA, Marti TM. Tièche CC, et al. Among authors: riether c. Neoplasia. 2019 Feb;21(2):185-196. doi: 10.1016/j.neo.2018.09.008. Epub 2018 Dec 27. Neoplasia. 2019. PMID: 30591423 Free PMC article.
TNIK signaling imprints CD8+ T cell memory formation early after priming.
Jaeger-Ruckstuhl CA, Hinterbrandner M, Höpner S, Correnti CE, Lüthi U, Friedli O, Freigang S, Al Sayed MF, Bührer ED, Amrein MA, Schürch CM, Radpour R, Riether C, Ochsenbein AF. Jaeger-Ruckstuhl CA, et al. Among authors: riether c. Nat Commun. 2020 Apr 2;11(1):1632. doi: 10.1038/s41467-020-15413-7. Nat Commun. 2020. PMID: 32242021 Free PMC article.
Targeting CD70 with cusatuzumab eliminates acute myeloid leukemia stem cells in patients treated with hypomethylating agents.
Riether C, Pabst T, Höpner S, Bacher U, Hinterbrandner M, Banz Y, Müller R, Manz MG, Gharib WH, Francisco D, Bruggmann R, van Rompaey L, Moshir M, Delahaye T, Gandini D, Erzeel E, Hultberg A, Fung S, de Haard H, Leupin N, Ochsenbein AF. Riether C, et al. Nat Med. 2020 Sep;26(9):1459-1467. doi: 10.1038/s41591-020-0910-8. Epub 2020 Jun 29. Nat Med. 2020. PMID: 32601337 Clinical Trial.
Chemotherapy negatively impacts the tumor immune microenvironment in NSCLC: an analysis of pre- and post-treatment biopsies in the multi-center SAKK19/09 study.
Amrein MA, Bührer ED, Amrein ML, Li Q, Rothschild S, Riether C, Jaggi R, Savic-Prince S, Bubendorf L, Gautschi O, Ochsenbein AF. Amrein MA, et al. Among authors: riether c. Cancer Immunol Immunother. 2021 Feb;70(2):405-415. doi: 10.1007/s00262-020-02688-4. Epub 2020 Aug 7. Cancer Immunol Immunother. 2021. PMID: 32767058 Free PMC article.
Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage.
Deng H, Gao Y, Trappetti V, Hertig D, Karatkevich D, Losmanova T, Urzi C, Ge H, Geest GA, Bruggmann R, Djonov V, Nuoffer JM, Vermathen P, Zamboni N, Riether C, Ochsenbein A, Peng RW, Kocher GJ, Schmid RA, Dorn P, Marti TM. Deng H, et al. Among authors: riether c. Cell Mol Life Sci. 2022 Jul 25;79(8):445. doi: 10.1007/s00018-022-04453-5. Cell Mol Life Sci. 2022. PMID: 35877003 Free PMC article.
70 results