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Identification of HSP90 inhibitors as a novel class of senolytics.
Fuhrmann-Stroissnigg H, Ling YY, Zhao J, McGowan SJ, Zhu Y, Brooks RW, Grassi D, Gregg SQ, Stripay JL, Dorronsoro A, Corbo L, Tang P, Bukata C, Ring N, Giacca M, Li X, Tchkonia T, Kirkland JL, Niedernhofer LJ, Robbins PD. Fuhrmann-Stroissnigg H, et al. Among authors: ring n. Nat Commun. 2017 Sep 4;8(1):422. doi: 10.1038/s41467-017-00314-z. Nat Commun. 2017. PMID: 28871086 Free PMC article.
High-throughput screening discovers antifibrotic properties of haloperidol by hindering myofibroblast activation.
Rehman M, Vodret S, Braga L, Guarnaccia C, Celsi F, Rossetti G, Martinelli V, Battini T, Long C, Vukusic K, Kocijan T, Collesi C, Ring N, Skoko N, Giacca M, Del Sal G, Confalonieri M, Raspa M, Marcello A, Myers MP, Crovella S, Carloni P, Zacchigna S. Rehman M, et al. Among authors: ring n. JCI Insight. 2019 Apr 18;4(8):e123987. doi: 10.1172/jci.insight.123987. eCollection 2019 Apr 18. JCI Insight. 2019. PMID: 30996132 Free PMC article.
Intracoronary Cytoprotective Gene Therapy: A Study of VEGF-B167 in a Pre-Clinical Animal Model of Dilated Cardiomyopathy.
Woitek F, Zentilin L, Hoffman NE, Powers JC, Ottiger I, Parikh S, Kulczycki AM, Hurst M, Ring N, Wang T, Shaikh F, Gross P, Singh H, Kolpakov MA, Linke A, Houser SR, Rizzo V, Sabri A, Madesh M, Giacca M, Recchia FA. Woitek F, et al. Among authors: ring n. J Am Coll Cardiol. 2015 Jul 14;66(2):139-53. doi: 10.1016/j.jacc.2015.04.071. J Am Coll Cardiol. 2015. PMID: 26160630 Free PMC article.
miR-200 family members reduce senescence and restore idiopathic pulmonary fibrosis type II alveolar epithelial cell transdifferentiation.
Moimas S, Salton F, Kosmider B, Ring N, Volpe MC, Bahmed K, Braga L, Rehman M, Vodret S, Graziani ML, Wolfson MR, Marchetti N, Rogers TJ, Giacca M, Criner GJ, Zacchigna S, Confalonieri M. Moimas S, et al. Among authors: ring n. ERJ Open Res. 2019 Dec 16;5(4):00138-2019. doi: 10.1183/23120541.00138-2019. eCollection 2019 Oct. ERJ Open Res. 2019. PMID: 31857992 Free PMC article.
Wet-dry-wet drug screen leads to the synthesis of TS1, a novel compound reversing lung fibrosis through inhibition of myofibroblast differentiation.
Ring NAR, Volpe MC, Stepišnik T, Mamolo MG, Panov P, Kocev D, Vodret S, Fortuna S, Calabretti A, Rehman M, Colliva A, Marchesan P, Camparini L, Marcuzzo T, Bussani R, Scarabellotto S, Confalonieri M, Pham TX, Ligresti G, Caporarello N, Loffredo FS, Zampieri D, Džeroski S, Zacchigna S. Ring NAR, et al. Cell Death Dis. 2021 Dec 17;13(1):2. doi: 10.1038/s41419-021-04439-4. Cell Death Dis. 2021. PMID: 34916483 Free PMC article.
Intercellular transfer of miR-200c-3p impairs the angiogenic capacity of cardiac endothelial cells.
Ottaviani L, Juni RP, de Abreu RC, Sansonetti M, Sampaio-Pinto V, Halkein J, Hegenbarth JC, Ring N, Knoops K, Kocken JMM, Jesus C, Ernault AC, El Azzouzi H, Rühle F, Olieslagers S, Fernandes H, Ferreira L, Braga L, Stoll M, Nascimento DS, de Windt LJ, da Costa Martins PA. Ottaviani L, et al. Among authors: ring n. Mol Ther. 2022 Jun 1;30(6):2257-2273. doi: 10.1016/j.ymthe.2022.03.002. Epub 2022 Mar 9. Mol Ther. 2022. PMID: 35278675 Free PMC article.
128 results