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The early history of intracellular cysteine proteinase inhibitors.
Rinne A. Rinne A. Front Biosci (Elite Ed). 2010 Jun 1;2:793-5. doi: 10.2741/e139. Front Biosci (Elite Ed). 2010. PMID: 20515751 Review.
Thus it is very important to give a balanced view of the past as well as the present of the field discussed in those papers. In the present letter I wish to complement a review article previously published in Frontiers in Bioscience....
Thus it is very important to give a balanced view of the past as well as the present of the field discussed in those papers. In the p …
The 43 kDa papain inhibitor in normal and diseased skin.
Aho H, Joronen I, Järvinen M, Rinne A, Hopsu-Havu VK. Aho H, et al. J Cutan Pathol. 1988 Dec;15(6):367-73. doi: 10.1111/j.1600-0560.1988.tb00567.x. J Cutan Pathol. 1988. PMID: 3220995
Immunolocalization of cysteine proteinases (cathepsins) and cysteine proteinase inhibitors (salarin and salmon kininogen) in Atlantic salmon, Salmo salar.
Tähtinen V, Weber E, Günther D, Ylönen A, Kalkkinen N, Olsen R, Järvinen M, Söderström KO, Rinne A, Björklund H, Bøgwald J. Tähtinen V, et al. Cell Tissue Res. 2002 Nov;310(2):213-22. doi: 10.1007/s00441-002-0627-7. Epub 2002 Aug 28. Cell Tissue Res. 2002. PMID: 12397376
Mostly, the staining had a diffuse cytoplasmic localization. In the liver some hepatocytes were strongly positive for salarin and salmon kininogen. ...Mostly, the staining showed a prominent lysosomal localization. In head kidney large macrophage-like cells were pos …
Mostly, the staining had a diffuse cytoplasmic localization. In the liver some hepatocytes were strongly positive for salarin and sal …
Cystatin B as an intracellular modulator of bone resorption.
Laitala-Leinonen T, Rinne R, Saukko P, Väänänen HK, Rinne A. Laitala-Leinonen T, et al. Matrix Biol. 2006 Apr;25(3):149-57. doi: 10.1016/j.matbio.2005.10.005. Matrix Biol. 2006. PMID: 16321512
Cathepsin K is a major osteoclast proteinase needed for bone resorption, although osteoclasts also express a variety of other cysteine- and matrix metalloproteinases that are involved in bone remodellation. Cystatin B, an intracellular cysteine proteinase inhibitor, …
Cathepsin K is a major osteoclast proteinase needed for bone resorption, although osteoclasts also express a variety of other …
Acid cysteine proteinase inhibitor in cutaneous lymphocytic infiltrates.
Aho HJ, Ping W, Söderström KO, Rinne A, Rinne R, Hopsu-Havu VK. Aho HJ, et al. Am J Dermatopathol. 1995 Apr;17(2):115-25. doi: 10.1097/00000372-199504000-00002. Am J Dermatopathol. 1995. PMID: 8600775
Acid cysteine proteinase inhibitor (ACPI, cystatin A) is normally present in squamous epithelium and dendritic cells of lymphoid follicles. ...The B-cell-type lesions with well-developed follicles and germinal centers showed a pronounced ACPI expression in dendritic …
Acid cysteine proteinase inhibitor (ACPI, cystatin A) is normally present in squamous epithelium and dendritic cells of lymphoid foll …
Biological and prognostic role of acid cysteine proteinase inhibitor (ACPI, cystatin A) in non-small-cell lung cancer.
Leinonen T, Pirinen R, Böhm J, Johansson R, Rinne A, Weber E, Kosma VM. Leinonen T, et al. J Clin Pathol. 2007 May;60(5):515-9. doi: 10.1136/jcp.2006.038711. Epub 2006 Jun 21. J Clin Pathol. 2007. PMID: 16790691 Free PMC article.
RESULTS: A normal bronchial epithelium showed positive staining for ACPI in the basal cells, whereas the upper two-thirds of the dysplastic epithelium was ACPI positive. ...CONCLUSIONS: ACPI expression is linked with the malignant transformation of the bronchial epithelium …
RESULTS: A normal bronchial epithelium showed positive staining for ACPI in the basal cells, whereas the upper two-thirds of the dysp …
Atlantic salmon (Salmo salar L.) skin contains a novel kininogen and another cysteine proteinase inhibitor.
Ylönen A, Rinne A, Herttuainen J, Bogwald J, Järvinen M, Kalkkinen N. Ylönen A, et al. Eur J Biochem. 1999 Dec;266(3):1066-72. doi: 10.1046/j.1432-1327.1999.00950.x. Eur J Biochem. 1999. PMID: 10583403
One of these, salmon kininogen, has a molecular mass of 52 kDa as determined by matrix-assisted laser desorption/ionization time-of-flight MS, is multiply charged with pI values of 4.0, 4.2 and 4.6 and shows homology to kininogens including the bradykinin motif. The other, …
One of these, salmon kininogen, has a molecular mass of 52 kDa as determined by matrix-assisted laser desorption/ionization time-of-f …
Separation of cysteine proteinase inhibitors from psoriatic scale.
Hopsu-Havu VK, Järvinen M, Rinne A. Hopsu-Havu VK, et al. Br J Dermatol. 1983 Jul;109 Suppl 25:77-85. Br J Dermatol. 1983. PMID: 6407510
The slightly alkaline inhibitor with mol.wt 37,000 reacted in immunodiffusion with a commercial rabbit polyvalent antiserum. The abundance of cysteine proteinase inhibitors in the psoriatic lesion is considered as a local effort to compensate for the high cysteine p …
The slightly alkaline inhibitor with mol.wt 37,000 reacted in immunodiffusion with a commercial rabbit polyvalent antiserum. The abun …
Cysteine proteinase inhibitors in psoriatic epidermis.
Hopsu-Havu VK, Joronen IA, Järvinen M, Rinne A. Hopsu-Havu VK, et al. Arch Dermatol Res. 1983;275(5):305-9. doi: 10.1007/BF00417202. Arch Dermatol Res. 1983. PMID: 6607037
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