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Brain abscesses due to Citrobacter koseri in a pair of twins.
Etuwewe O, Kulshrestha R, Sangra M, Riordan A. Etuwewe O, et al. Pediatr Infect Dis J. 2009 Nov;28(11):1035. doi: 10.1097/INF.0b013e3181b6b064. Pediatr Infect Dis J. 2009. PMID: 19859021 No abstract available.
Lopinavir dosing in HIV-infected children in the United Kingdom and Ireland.
Donegan K, Doerholt K, Judd A, Lyall H, Menson E, Butler K, Tookey P, Riordan A, Shingadia D, Tudor-Williams G, Gibb DM, Walker AS; Collaborative HIV Paediatric Study (CHIPS). Donegan K, et al. Pediatr Infect Dis J. 2013 Jan;32(1):45-50. doi: 10.1097/INF.0b013e31827842c9. Pediatr Infect Dis J. 2013. PMID: 23076384
The licensed total daily dose is 460 mg/m², whereas the original study, reporting excellent viral load (VL) suppression, used a higher 600 mg/m² dose. ...For those receiving lopinavir/r for ≥6 months, there was a greater chance of VL <400 copies/mL with higher do …
The licensed total daily dose is 460 mg/m², whereas the original study, reporting excellent viral load (VL) suppression, used a highe …
Tenofovir use in human immunodeficiency virus-1-infected children in the United kingdom and Ireland.
Riordan A, Judd A, Boyd K, Cliff D, Doerholt K, Lyall H, Menson E, Butler K, Gibb D; Collaborative HIV Paediatric Study. Riordan A, et al. Pediatr Infect Dis J. 2009 Mar;28(3):204-9. doi: 10.1097/INF.0b013e31818c8d2c. Pediatr Infect Dis J. 2009. PMID: 19209091 Clinical Trial.
We describe the use of TDF in a cohort of HIV-1-infected children in the United Kingdom and Ireland. METHODS: Children ever prescribed TDF and followed in the Collaborative HIV Pediatric Study cohort since 2001 were included in analyses of dosing, adverse events, and virol …
We describe the use of TDF in a cohort of HIV-1-infected children in the United Kingdom and Ireland. METHODS: Children ever prescribe …
Outcomes for human immunodeficiency virus-1-infected infants in the United kingdom and Republic of Ireland in the era of effective antiretroviral therapy.
Doerholt K, Duong T, Tookey P, Butler K, Lyall H, Sharland M, Novelli V, Riordan A, Dunn D, Walker AS, Gibb DM; Collaborative HIV Paediatric Study. Doerholt K, et al. Pediatr Infect Dis J. 2006 May;25(5):420-6. doi: 10.1097/01.inf.0000214994.44346.d3. Pediatr Infect Dis J. 2006. PMID: 16645506
The use of ART and CD4 and HIV-1 RNA responses were assessed in a subset in the Collaborative HIV Pediatric Study. RESULTS: Among 481 infants, mortality was lower in those born after 1997 (HR 0.30; P < 0.001), with no significant change in progression to AIDS. ...
The use of ART and CD4 and HIV-1 RNA responses were assessed in a subset in the Collaborative HIV Pediatric Study. RESULTS: Among 481 …
Rapid Identification of Microorganisms by FilmArray Blood Culture Identification Panel Improves Clinical Management in Children.
Ray ST, Drew RJ, Hardiman F, Pizer B, Riordan A. Ray ST, et al. Pediatr Infect Dis J. 2016 May;35(5):e134-8. doi: 10.1097/INF.0000000000001065. Pediatr Infect Dis J. 2016. PMID: 26808722
BACKGROUND: Blood cultures are a common investigation for children admitted to hospital. In routine practice, it takes at least 24 hours to identify an organism as a contaminant or clinically significant. ...Future studies should focus on how best to use this techno …
BACKGROUND: Blood cultures are a common investigation for children admitted to hospital. In routine practice, it takes at least 24 ho …
Clinical and microbiologic features guiding treatment recommendations for brain abscesses in children.
Felsenstein S, Williams B, Shingadia D, Coxon L, Riordan A, Demetriades AK, Chandler CL, Bassi S, Koutoumanou E, Stapleton S, Sharland M, Bryant PA. Felsenstein S, et al. Pediatr Infect Dis J. 2013 Feb;32(2):129-35. doi: 10.1097/INF.0b013e3182748d6e. Pediatr Infect Dis J. 2013. PMID: 23001027 Clinical Trial.
BACKGROUND: There are no guidelines for the management of brain abscesses in children, and there is a paucity of recent data describing clinical and microbiologic features. ...Meropenem potentially would be a better choice in the immunocompromised. A prospect …
BACKGROUND: There are no guidelines for the management of brain abscesses in children, and there is a paucity of recent data describi …
Measles reimmunization may not be effective in protecting HIV-infected children.
Rowson K, Tan A, Donaghy S, Doerholt K, Heath P, Riordan A. Rowson K, et al. Pediatr Infect Dis J. 2015 May;34(5):552. doi: 10.1097/INF.0000000000000673. Pediatr Infect Dis J. 2015. PMID: 25876100 No abstract available.
Decline in mortality, AIDS, and hospital admissions in perinatally HIV-1 infected children in the United Kingdom and Ireland.
Gibb DM, Duong T, Tookey PA, Sharland M, Tudor-Williams G, Novelli V, Butler K, Riordan A, Farrelly L, Masters J, Peckham CS, Dunn DT; National Study of HIV in Pregnancy and Childhood Collaborative HIV Paediatric Study. Gibb DM, et al. BMJ. 2003 Nov 1;327(7422):1019. doi: 10.1136/bmj.327.7422.1019. BMJ. 2003. PMID: 14593035 Free PMC article.
DESIGN: Active surveillance through the national study of HIV in pregnancy and childhood (NSHPC) and additional data from a subset of children in the collaborative HIV paediatric study (CHIPS). ...
DESIGN: Active surveillance through the national study of HIV in pregnancy and childhood (NSHPC) and additional data from a subset of …
Duration of intravenous antibiotic therapy for children with acute osteomyelitis or septic arthritis: a feasibility study.
de Graaf H, Sukhtankar P, Arch B, Ahmad N, Lees A, Bennett A, Spowart C, Hickey H, Jeanes A, Armon K, Riordan A, Herberg J, Hackett S, Gamble C, Shingadia D, Pallett A, Clarke SC, Henman P, Emonts M, Sharland M, Finn A, Pollard AJ, Powell C, Marsh P, Ballinger C, Williamson PR, Clarke NM, Faust SN. de Graaf H, et al. Health Technol Assess. 2017 Sep;21(48):1-164. doi: 10.3310/hta21480. Health Technol Assess. 2017. PMID: 28862129 Free PMC article.
DESIGN: (1) A prospective service evaluation (cohort study) to determine the current disease spectrum and UK clinical practice in paediatric OM/SA; (2) a prospective cohort substudy to assess the use of targeted polymerase chain reaction (PCR) in diagnosing paediatr …
DESIGN: (1) A prospective service evaluation (cohort study) to determine the current disease spectrum and UK clinical practice in pae …
Effect of tenofovir disoproxil fumarate on risk of renal abnormality in HIV-1-infected children on antiretroviral therapy: a nested case-control study.
Judd A, Boyd KL, Stöhr W, Dunn D, Butler K, Lyall H, Sharland M, Shingadia D, Riordan A, Gibb DM. Judd A, et al. AIDS. 2010 Feb 20;24(4):525-34. doi: 10.1097/QAD.0b013e3283333680. AIDS. 2010. PMID: 20139752
OBJECTIVE: To investigate the association between tenofovir disoproxil fumarate (TDF) use and renal abnormality in a large cohort of HIV-1-infected children on antiretroviral therapy (ART). ...METHODS: Patients were from the Collaborative HIV Paediatric Study, a coh …
OBJECTIVE: To investigate the association between tenofovir disoproxil fumarate (TDF) use and renal abnormality in a large cohort of …
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