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Suppression of inflammatory and neuropathic pain by uncoupling CRMP-2 from the presynaptic Ca²⁺ channel complex.
Brittain JM, Duarte DB, Wilson SM, Zhu W, Ballard C, Johnson PL, Liu N, Xiong W, Ripsch MS, Wang Y, Fehrenbacher JC, Fitz SD, Khanna M, Park CK, Schmutzler BS, Cheon BM, Due MR, Brustovetsky T, Ashpole NM, Hudmon A, Meroueh SO, Hingtgen CM, Brustovetsky N, Ji RR, Hurley JH, Jin X, Shekhar A, Xu XM, Oxford GS, Vasko MR, White FA, Khanna R. Brittain JM, et al. Among authors: ripsch ms. Nat Med. 2011 Jun 5;17(7):822-9. doi: 10.1038/nm.2345. Nat Med. 2011. PMID: 21642979 Free PMC article.
CRMP-2 peptide mediated decrease of high and low voltage-activated calcium channels, attenuation of nociceptor excitability, and anti-nociception in a model of AIDS therapy-induced painful peripheral neuropathy.
Piekarz AD, Due MR, Khanna M, Wang B, Ripsch MS, Wang R, Meroueh SO, Vasko MR, White FA, Khanna R. Piekarz AD, et al. Among authors: ripsch ms. Mol Pain. 2012 Jul 24;8:54. doi: 10.1186/1744-8069-8-54. Mol Pain. 2012. PMID: 22828369 Free PMC article.
CXCR4 signaling mediates morphine-induced tactile hyperalgesia.
Wilson NM, Jung H, Ripsch MS, Miller RJ, White FA. Wilson NM, et al. Among authors: ripsch ms. Brain Behav Immun. 2011 Mar;25(3):565-73. doi: 10.1016/j.bbi.2010.12.014. Epub 2010 Dec 28. Brain Behav Immun. 2011. PMID: 21193025 Free PMC article.
Merging Structural Motifs of Functionalized Amino Acids and α-Aminoamides Results in Novel Anticonvulsant Compounds with Significant Effects on Slow and Fast Inactivation of Voltage-gated Sodium Channels and in the Treatment of Neuropathic Pain.
Wang Y, Wilson SM, Brittain JM, Ripsch MS, Salomé C, Park KD, White FA, Khanna R, Kohn H. Wang Y, et al. Among authors: ripsch ms. ACS Chem Neurosci. 2011 Jun 15;2(6):317-322. doi: 10.1021/cn200024z. ACS Chem Neurosci. 2011. PMID: 21765969 Free PMC article.
Further insights into the antinociceptive potential of a peptide disrupting the N-type calcium channel-CRMP-2 signaling complex.
Wilson SM, Brittain JM, Piekarz AD, Ballard CJ, Ripsch MS, Cummins TR, Hurley JH, Khanna M, Hammes NM, Samuels BC, White FA, Khanna R. Wilson SM, et al. Among authors: ripsch ms. Channels (Austin). 2011 Sep-Oct;5(5):449-56. doi: 10.4161/chan.5.5.17363. Epub 2011 Sep 1. Channels (Austin). 2011. PMID: 21829088 Free PMC article.
27 results