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Mitochondrial hormesis links low-dose arsenite exposure to lifespan extension.
Schmeisser S, Schmeisser K, Weimer S, Groth M, Priebe S, Fazius E, Kuhlow D, Pick D, Einax JW, Guthke R, Platzer M, Zarse K, Ristow M. Schmeisser S, et al. Among authors: Ristow M. Aging Cell. 2013 Jun;12(3):508-17. doi: 10.1111/acel.12076. Epub 2013 May 6. Aging Cell. 2013. PMID: 23534459 Free PMC article.
Extension of life span by impaired glucose metabolism in Caenorhabditis elegans is accompanied by structural rearrangements of the transcriptomic network.
Priebe S, Menzel U, Zarse K, Groth M, Platzer M, Ristow M, Guthke R. Priebe S, et al. Among authors: Ristow M. PLoS One. 2013 Oct 30;8(10):e77776. doi: 10.1371/journal.pone.0077776. eCollection 2013. PLoS One. 2013. PMID: 24204961 Free PMC article.
Mitochondrial DNA copy number and function decrease with age in the short-lived fish Nothobranchius furzeri.
Hartmann N, Reichwald K, Wittig I, Dröse S, Schmeisser S, Lück C, Hahn C, Graf M, Gausmann U, Terzibasi E, Cellerino A, Ristow M, Brandt U, Platzer M, Englert C. Hartmann N, et al. Among authors: Ristow M. Aging Cell. 2011 Oct;10(5):824-31. doi: 10.1111/j.1474-9726.2011.00723.x. Epub 2011 Jun 27. Aging Cell. 2011. PMID: 21624037
Longitudinal RNA-Seq Analysis of Vertebrate Aging Identifies Mitochondrial Complex I as a Small-Molecule-Sensitive Modifier of Lifespan.
Baumgart M, Priebe S, Groth M, Hartmann N, Menzel U, Pandolfini L, Koch P, Felder M, Ristow M, Englert C, Guthke R, Platzer M, Cellerino A. Baumgart M, et al. Among authors: Ristow M. Cell Syst. 2016 Feb 24;2(2):122-32. doi: 10.1016/j.cels.2016.01.014. Epub 2016 Feb 24. Cell Syst. 2016. PMID: 27135165
Branched-chain amino acid catabolism is a conserved regulator of physiological ageing.
Mansfeld J, Urban N, Priebe S, Groth M, Frahm C, Hartmann N, Gebauer J, Ravichandran M, Dommaschk A, Schmeisser S, Kuhlow D, Monajembashi S, Bremer-Streck S, Hemmerich P, Kiehntopf M, Zamboni N, Englert C, Guthke R, Kaleta C, Platzer M, Sühnel J, Witte OW, Zarse K, Ristow M. Mansfeld J, et al. Among authors: Ristow M. Nat Commun. 2015 Dec 1;6:10043. doi: 10.1038/ncomms10043. Nat Commun. 2015. PMID: 26620638 Free PMC article.
Impairment of insulin signalling in peripheral tissue fails to extend murine lifespan.
Merry TL, Kuhlow D, Laube B, Pöhlmann D, Pfeiffer AFH, Kahn CR, Ristow M, Zarse K. Merry TL, et al. Among authors: Ristow M. Aging Cell. 2017 Aug;16(4):761-772. doi: 10.1111/acel.12610. Epub 2017 May 22. Aging Cell. 2017. PMID: 28544360 Free PMC article.
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