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PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion.
Caino MC, Ghosh JC, Chae YC, Vaira V, Rivadeneira DB, Faversani A, Rampini P, Kossenkov AV, Aird KM, Zhang R, Webster MR, Weeraratna AT, Bosari S, Languino LR, Altieri DC. Caino MC, et al. Among authors: Rivadeneira DB. Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):8638-43. doi: 10.1073/pnas.1500722112. Epub 2015 Jun 29. Proc Natl Acad Sci U S A. 2015. PMID: 26124089 Free PMC article.
Syntaphilin controls a mitochondrial rheostat for proliferation-motility decisions in cancer.
Caino MC, Seo JH, Wang Y, Rivadeneira DB, Gabrilovich DI, Kim ET, Weeraratna AT, Languino LR, Altieri DC. Caino MC, et al. Among authors: Rivadeneira DB. J Clin Invest. 2017 Oct 2;127(10):3755-3769. doi: 10.1172/JCI93172. Epub 2017 Sep 11. J Clin Invest. 2017. PMID: 28891816 Free PMC article.
The Mitochondrial Unfoldase-Peptidase Complex ClpXP Controls Bioenergetics Stress and Metastasis.
Seo JH, Rivadeneira DB, Caino MC, Chae YC, Speicher DW, Tang HY, Vaira V, Bosari S, Palleschi A, Rampini P, Kossenkov AV, Languino LR, Altieri DC. Seo JH, et al. Among authors: Rivadeneira DB. PLoS Biol. 2016 Jul 7;14(7):e1002507. doi: 10.1371/journal.pbio.1002507. eCollection 2016 Jul. PLoS Biol. 2016. PMID: 27389535 Free PMC article.
Association of RB/p16-pathway perturbations with DCIS recurrence: dependence on tumor versus tissue microenvironment.
Witkiewicz AK, Rivadeneira DB, Ertel A, Kline J, Hyslop T, Schwartz GF, Fortina P, Knudsen ES. Witkiewicz AK, et al. Among authors: Rivadeneira DB. Am J Pathol. 2011 Sep;179(3):1171-8. doi: 10.1016/j.ajpath.2011.05.043. Epub 2011 Jul 12. Am J Pathol. 2011. PMID: 21756866 Free PMC article.
Oxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution: A new paradigm for understanding tumor metabolism, the field effect and genomic instability in cancer cells.
Martinez-Outschoorn UE, Balliet RM, Rivadeneira DB, Chiavarina B, Pavlides S, Wang C, Whitaker-Menezes D, Daumer KM, Lin Z, Witkiewicz AK, Flomenberg N, Howell A, Pestell RG, Knudsen ES, Sotgia F, Lisanti MP. Martinez-Outschoorn UE, et al. Among authors: Rivadeneira DB. Cell Cycle. 2010 Aug 15;9(16):3256-76. doi: 10.4161/cc.9.16.12553. Epub 2010 Aug 28. Cell Cycle. 2010. PMID: 20814239 Free PMC article.
CDK4/6 inhibition antagonizes the cytotoxic response to anthracycline therapy.
McClendon AK, Dean JL, Rivadeneira DB, Yu JE, Reed CA, Gao E, Farber JL, Force T, Koch WJ, Knudsen ES. McClendon AK, et al. Among authors: Rivadeneira DB. Cell Cycle. 2012 Jul 15;11(14):2747-55. doi: 10.4161/cc.21127. Epub 2012 Jul 15. Cell Cycle. 2012. PMID: 22751436 Free PMC article.
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