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1,201 results
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siRNA and innate immunity.
Robbins M, Judge A, MacLachlan I. Robbins M, et al. Oligonucleotides. 2009 Jun;19(2):89-102. doi: 10.1089/oli.2009.0180. Oligonucleotides. 2009. PMID: 19441890 Review.
Protection against lethal Marburg virus infection mediated by lipid encapsulated small interfering RNA.
Ursic-Bedoya R, Mire CE, Robbins M, Geisbert JB, Judge A, MacLachlan I, Geisbert TW. Ursic-Bedoya R, et al. Among authors: robbins m. J Infect Dis. 2014 Feb 15;209(4):562-70. doi: 10.1093/infdis/jit465. Epub 2013 Aug 29. J Infect Dis. 2014. PMID: 23990568 Free PMC article.
siRNA rescues nonhuman primates from advanced Marburg and Ravn virus disease.
Thi EP, Mire CE, Lee AC, Geisbert JB, Ursic-Bedoya R, Agans KN, Robbins M, Deer DJ, Cross RW, Kondratowicz AS, Fenton KA, MacLachlan I, Geisbert TW. Thi EP, et al. Among authors: robbins m. J Clin Invest. 2017 Dec 1;127(12):4437-4448. doi: 10.1172/JCI96185. Epub 2017 Nov 6. J Clin Invest. 2017. PMID: 29106386 Free PMC article.
Rescue of non-human primates from advanced Sudan ebolavirus infection with lipid encapsulated siRNA.
Thi EP, Lee AC, Geisbert JB, Ursic-Bedoya R, Agans KN, Robbins M, Deer DJ, Fenton KA, Kondratowicz AS, MacLachlan I, Geisbert TW, Mire CE. Thi EP, et al. Among authors: robbins m. Nat Microbiol. 2016 Aug 22;1(10):16142. doi: 10.1038/nmicrobiol.2016.142. Nat Microbiol. 2016. PMID: 27670117 Free PMC article.
Marburg virus infection in nonhuman primates: Therapeutic treatment by lipid-encapsulated siRNA.
Thi EP, Mire CE, Ursic-Bedoya R, Geisbert JB, Lee ACH, Agans KN, Robbins M, Deer DJ, Fenton KA, MacLachlan I, Geisbert TW. Thi EP, et al. Among authors: robbins m. Sci Transl Med. 2014 Aug 20;6(250):250ra116. doi: 10.1126/scitranslmed.3009706. Sci Transl Med. 2014. PMID: 25143366 Free PMC article.
Confirming the RNAi-mediated mechanism of action of siRNA-based cancer therapeutics in mice.
Judge AD, Robbins M, Tavakoli I, Levi J, Hu L, Fronda A, Ambegia E, McClintock K, MacLachlan I. Judge AD, et al. Among authors: robbins m. J Clin Invest. 2009 Mar;119(3):661-73. doi: 10.1172/JCI37515. Epub 2009 Feb 23. J Clin Invest. 2009. PMID: 19229107 Free PMC article.
2'-O-methyl-modified RNAs act as TLR7 antagonists.
Robbins M, Judge A, Liang L, McClintock K, Yaworski E, MacLachlan I. Robbins M, et al. Mol Ther. 2007 Sep;15(9):1663-9. doi: 10.1038/sj.mt.6300240. Epub 2007 Jun 19. Mol Ther. 2007. PMID: 17579574
Misinterpreting the therapeutic effects of small interfering RNA caused by immune stimulation.
Robbins M, Judge A, Ambegia E, Choi C, Yaworski E, Palmer L, McClintock K, MacLachlan I. Robbins M, et al. Hum Gene Ther. 2008 Oct;19(10):991-9. doi: 10.1089/hum.2008.131. Hum Gene Ther. 2008. PMID: 18713023
Nuclear factor-kappaB translocation mediates double-stranded ribonucleic acid-induced NIT-1 beta-cell apoptosis and up-regulates caspase-12 and tumor necrosis factor receptor-associated ligand (TRAIL).
Robbins MA, Maksumova L, Pocock E, Chantler JK. Robbins MA, et al. Endocrinology. 2003 Oct;144(10):4616-25. doi: 10.1210/en.2003-0266. Epub 2003 Jun 26. Endocrinology. 2003. PMID: 12960048
Evidence that binding of cucumber necrosis virus to vector zoospores involves recognition of oligosaccharides.
Kakani K, Robbins M, Rochon D. Kakani K, et al. Among authors: robbins m. J Virol. 2003 Apr;77(7):3922-8. doi: 10.1128/jvi.77.7.3922-3928.2003. J Virol. 2003. PMID: 12634352 Free PMC article.
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