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Sphingolipid subtypes differentially control proinsulin processing and systemic glucose homeostasis.
Griess K, Rieck M, Müller N, Karsai G, Hartwig S, Pelligra A, Hardt R, Schlegel C, Kuboth J, Uhlemeyer C, Trenkamp S, Jeruschke K, Weiss J, Peifer-Weiss L, Xu W, Cames S, Yi X, Cnop M, Beller M, Stark H, Kondadi AK, Reichert AS, Markgraf D, Wammers M, Häussinger D, Kuss O, Lehr S, Eizirik D, Lickert H, Lammert E, Roden M, Winter D, Al-Hasani H, Höglinger D, Hornemann T, Brüning JC, Belgardt BF. Griess K, et al. Among authors: hardt r. Nat Cell Biol. 2023 Jan;25(1):20-29. doi: 10.1038/s41556-022-01027-2. Epub 2022 Dec 21. Nat Cell Biol. 2023. PMID: 36543979 Free PMC article.
Hyperactivity of the non-canonical inflammasome in SPG11 and SPG48.
Afzal MA, Ghait M, Hussain A, Siegmund A, Tuchscherr L, Babic P, Press AT, Hardt R, Winter D, Rödiger A, Schüle R, Fielitz J, Bauer M, Hübner CA. Afzal MA, et al. Among authors: hardt r. EBioMedicine. 2025 Nov;121:105985. doi: 10.1016/j.ebiom.2025.105985. Epub 2025 Oct 24. EBioMedicine. 2025. PMID: 41138668 Free PMC article.
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