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Physiological actions and clinical applications of transforming growth factor-beta (TGF-beta).
Roberts AB, Sporn MB. Roberts AB, et al. Growth Factors. 1993;8(1):1-9. doi: 10.3109/08977199309029129. Growth Factors. 1993. PMID: 8448037 Review. No abstract available.
Transforming growth factor-beta/Smad3 signaling regulates insulin gene transcription and pancreatic islet beta-cell function.
Lin HM, Lee JH, Yadav H, Kamaraju AK, Liu E, Zhigang D, Vieira A, Kim SJ, Collins H, Matschinsky F, Harlan DM, Roberts AB, Rane SG. Lin HM, et al. Among authors: roberts ab. J Biol Chem. 2009 May 1;284(18):12246-57. doi: 10.1074/jbc.M805379200. Epub 2009 Mar 5. J Biol Chem. 2009. PMID: 19265200 Free PMC article.
RLP, a novel Ras-like protein, is an immediate-early transforming growth factor-beta (TGF-beta) target gene that negatively regulates transcriptional activity induced by TGF-beta.
Piek E, Van Dinther M, Parks WT, Sallee JM, B├Âttinger EP, Roberts AB, Ten Dijke P. Piek E, et al. Among authors: roberts ab. Biochem J. 2004 Oct 1;383(Pt 1):187-99. doi: 10.1042/BJ20040774. Biochem J. 2004. PMID: 15239668 Free PMC article.
Transient tumor-fibroblast interactions increase tumor cell malignancy by a TGF-Beta mediated mechanism in a mouse xenograft model of breast cancer.
Stuelten CH, Busch JI, Tang B, Flanders KC, Oshima A, Sutton E, Karpova TS, Roberts AB, Wakefield LM, Niederhuber JE. Stuelten CH, et al. Among authors: roberts ab. PLoS One. 2010 Mar 23;5(3):e9832. doi: 10.1371/journal.pone.0009832. PLoS One. 2010. PMID: 20352126 Free PMC article.
Role of Rho/ROCK and p38 MAP kinase pathways in transforming growth factor-beta-mediated Smad-dependent growth inhibition of human breast carcinoma cells in vivo.
Kamaraju AK, Roberts AB. Kamaraju AK, et al. Among authors: roberts ab. J Biol Chem. 2005 Jan 14;280(2):1024-36. doi: 10.1074/jbc.M403960200. Epub 2004 Nov 1. J Biol Chem. 2005. PMID: 15520018
Amelioration of radiation-induced fibrosis: inhibition of transforming growth factor-beta signaling by halofuginone.
Xavier S, Piek E, Fujii M, Javelaud D, Mauviel A, Flanders KC, Samuni AM, Felici A, Reiss M, Yarkoni S, Sowers A, Mitchell JB, Roberts AB, Russo A. Xavier S, et al. Among authors: roberts ab. J Biol Chem. 2004 Apr 9;279(15):15167-76. doi: 10.1074/jbc.M309798200. Epub 2004 Jan 19. J Biol Chem. 2004. PMID: 14732719
Lateral signaling enhances TGF-beta response complexity.
Byfield SD, Roberts AB. Byfield SD, et al. Among authors: roberts ab. Trends Cell Biol. 2004 Mar;14(3):107-11. doi: 10.1016/j.tcb.2004.01.001. Trends Cell Biol. 2004. PMID: 15055198 Review.
The Discovery and Early Days of TGF-╬▓: A Historical Perspective.
Moses HL, Roberts AB, Derynck R. Moses HL, et al. Among authors: roberts ab. Cold Spring Harb Perspect Biol. 2016 Jul 1;8(7):a021865. doi: 10.1101/cshperspect.a021865. Cold Spring Harb Perspect Biol. 2016. PMID: 27328871 Free PMC article. Review.
Smad3 is key to TGF-beta-mediated epithelial-to-mesenchymal transition, fibrosis, tumor suppression and metastasis.
Roberts AB, Tian F, Byfield SD, Stuelten C, Ooshima A, Saika S, Flanders KC. Roberts AB, et al. Cytokine Growth Factor Rev. 2006 Feb-Apr;17(1-2):19-27. doi: 10.1016/j.cytogfr.2005.09.008. Epub 2005 Nov 11. Cytokine Growth Factor Rev. 2006. PMID: 16290023 Review.
Breast cancer cells induce stromal fibroblasts to express MMP-9 via secretion of TNF-alpha and TGF-beta.
Stuelten CH, DaCosta Byfield S, Arany PR, Karpova TS, Stetler-Stevenson WG, Roberts AB. Stuelten CH, et al. Among authors: roberts ab. J Cell Sci. 2005 May 15;118(Pt 10):2143-53. doi: 10.1242/jcs.02334. Epub 2005 Apr 26. J Cell Sci. 2005. PMID: 15855236
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