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264 results
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Conformational analysis of an alpha3beta1 integrin-binding peptide from thrombospondin-1: implications for antiangiogenic drug design.
Furrer J, Luy B, Basrur V, Roberts DD, Barchi JJ Jr. Furrer J, et al. Among authors: roberts dd. J Med Chem. 2006 Oct 19;49(21):6324-33. doi: 10.1021/jm060833l. J Med Chem. 2006. PMID: 17034138
Pro-adhesive and chemotactic activities of thrombospondin-1 for breast carcinoma cells are mediated by alpha3beta1 integrin and regulated by insulin-like growth factor-1 and CD98.
Chandrasekaran S, Guo NH, Rodrigues RG, Kaiser J, Roberts DD. Chandrasekaran S, et al. Among authors: roberts dd. J Biol Chem. 1999 Apr 16;274(16):11408-16. doi: 10.1074/jbc.274.16.11408. J Biol Chem. 1999. PMID: 10196234
Cooperation between thrombospondin-1 type 1 repeat peptides and alpha(v)beta(3) integrin ligands to promote melanoma cell spreading and focal adhesion kinase phosphorylation.
Sipes JM, Krutzsch HC, Lawler J, Roberts DD. Sipes JM, et al. Among authors: roberts dd. J Biol Chem. 1999 Aug 6;274(32):22755-62. doi: 10.1074/jbc.274.32.22755. J Biol Chem. 1999. PMID: 10428859
Conformational regulation of the fibronectin binding and alpha 3beta 1 integrin-mediated adhesive activities of thrombospondin-1.
Rodrigues RG, Guo N, Zhou L, Sipes JM, Williams SB, Templeton NS, Gralnick HR, Roberts DD. Rodrigues RG, et al. Among authors: roberts dd. J Biol Chem. 2001 Jul 27;276(30):27913-22. doi: 10.1074/jbc.M009518200. Epub 2001 May 17. J Biol Chem. 2001. PMID: 11358957
Cell contact-dependent activation of alpha3beta1 integrin modulates endothelial cell responses to thrombospondin-1.
Chandrasekaran L, He CZ, Al-Barazi H, Krutzsch HC, Iruela-Arispe ML, Roberts DD. Chandrasekaran L, et al. Among authors: roberts dd. Mol Biol Cell. 2000 Sep;11(9):2885-900. doi: 10.1091/mbc.11.9.2885. Mol Biol Cell. 2000. PMID: 10982388 Free PMC article.
Thrombospondin-1 promotes alpha3beta1 integrin-mediated adhesion and neurite-like outgrowth and inhibits proliferation of small cell lung carcinoma cells.
Guo N, Templeton NS, Al-Barazi H, Cashel JA, Sipes JM, Krutzsch HC, Roberts DD. Guo N, et al. Among authors: roberts dd. Cancer Res. 2000 Jan 15;60(2):457-66. Cancer Res. 2000. PMID: 10667601
Identification of an alpha(3)beta(1) integrin recognition sequence in thrombospondin-1.
Krutzsch HC, Choe BJ, Sipes JM, Guo Nh, Roberts DD. Krutzsch HC, et al. Among authors: roberts dd. J Biol Chem. 1999 Aug 20;274(34):24080-6. doi: 10.1074/jbc.274.34.24080. J Biol Chem. 1999. PMID: 10446179
Interaction of alpha9beta1 integrin with thrombospondin-1 promotes angiogenesis.
Staniszewska I, Zaveri S, Del Valle L, Oliva I, Rothman VL, Croul SE, Roberts DD, Mosher DF, Tuszynski GP, Marcinkiewicz C. Staniszewska I, et al. Among authors: roberts dd. Circ Res. 2007 May 11;100(9):1308-16. doi: 10.1161/01.RES.0000266662.98355.66. Epub 2007 Apr 5. Circ Res. 2007. PMID: 17413041
Identification of novel beta1 integrin binding sites in the type 1 and type 2 repeats of thrombospondin-1.
Calzada MJ, Annis DS, Zeng B, Marcinkiewicz C, Banas B, Lawler J, Mosher DF, Roberts DD. Calzada MJ, et al. Among authors: roberts dd. J Biol Chem. 2004 Oct 1;279(40):41734-43. doi: 10.1074/jbc.M406267200. Epub 2004 Aug 3. J Biol Chem. 2004. PMID: 15292271
Recognition of the N-terminal modules of thrombospondin-1 and thrombospondin-2 by alpha6beta1 integrin.
Calzada MJ, Sipes JM, Krutzsch HC, Yurchenco PD, Annis DS, Mosher DF, Roberts DD. Calzada MJ, et al. Among authors: roberts dd. J Biol Chem. 2003 Oct 17;278(42):40679-87. doi: 10.1074/jbc.M302014200. Epub 2003 Aug 8. J Biol Chem. 2003. PMID: 12909644
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