Roberts DM - Search Results

1

The Scaffolding Protein IQGAP1 Interacts with NLRC3 and Inhibits Type I IFN Production.

Tocker AM, Durocher E, Jacob KD, Trieschman KE, Talento SM, Rechnitzer AA, Roberts DM, Davis BK. Tocker AM, et al. Among authors: roberts dm. J Immunol. 2017 Oct 15;199(8):2896-2909. doi: 10.4049/jimmunol.1601370. Epub 2017 Sep 1. J Immunol. 2017. PMID: 28864474 Free PMC article.

2

The Poly(ADP-ribose) Polymerase Enzyme Tankyrase Antagonizes Activity of the β-Catenin Destruction Complex through ADP-ribosylation of Axin and APC2.

Croy HE, Fuller CN, Giannotti J, Robinson P, Foley AVA, Yamulla RJ, Cosgriff S, Greaves BD, von Kleeck RA, An HH, Powers CM, Tran JK, Tocker AM, Jacob KD, Davis BK, Roberts DM. Croy HE, et al. Among authors: roberts dm. J Biol Chem. 2016 Jun 10;291(24):12747-12760. doi: 10.1074/jbc.M115.705442. Epub 2016 Apr 11. J Biol Chem. 2016. PMID: 27068743 Free PMC article.

3

Self-association of the APC tumor suppressor is required for the assembly, stability, and activity of the Wnt signaling destruction complex.

Kunttas-Tatli E, Roberts DM, McCartney BM. Kunttas-Tatli E, et al. Among authors: roberts dm. Mol Biol Cell. 2014 Nov 1;25(21):3424-36. doi: 10.1091/mbc.E14-04-0885. Epub 2014 Sep 10. Mol Biol Cell. 2014. PMID: 25208568 Free PMC article.

4

Defining components of the ß-catenin destruction complex and exploring its regulation and mechanisms of action during development.

Roberts DM, Pronobis MI, Alexandre KM, Rogers GC, Poulton JS, Schneider DE, Jung KC, McKay DJ, Peifer M. Roberts DM, et al. PLoS One. 2012;7(2):e31284. doi: 10.1371/journal.pone.0031284. Epub 2012 Feb 16. PLoS One. 2012. PMID: 22359584 Free PMC article.

5

The two SAMP repeats and their phosphorylation state in Drosophila Adenomatous polyposis coli-2 play mechanistically distinct roles in negatively regulating Wnt signaling.

Kunttas-Tatli E, Von Kleeck RA, Greaves BD, Vinson D, Roberts DM, McCartney BM. Kunttas-Tatli E, et al. Among authors: roberts dm. Mol Biol Cell. 2015 Dec 1;26(24):4503-18. doi: 10.1091/mbc.E15-07-0515. Epub 2015 Oct 7. Mol Biol Cell. 2015. PMID: 26446838 Free PMC article.

6

Testing models of the APC tumor suppressor/β-catenin interaction reshapes our view of the destruction complex in Wnt signaling.

Yamulla RJ, Kane EG, Moody AE, Politi KA, Lock NE, Foley AV, Roberts DM. Yamulla RJ, et al. Among authors: roberts dm. Genetics. 2014 Aug;197(4):1285-302. doi: 10.1534/genetics.114.166496. Epub 2014 Jun 14. Genetics. 2014. PMID: 24931405 Free PMC article.

7

Genetics on the Fly: A Primer on the Drosophila Model System.

Hales KG, Korey CA, Larracuente AM, Roberts DM. Hales KG, et al. Among authors: roberts dm. Genetics. 2015 Nov;201(3):815-42. doi: 10.1534/genetics.115.183392. Genetics. 2015. PMID: 26564900 Free PMC article.

8

Supramolecular assembly of the beta-catenin destruction complex and the effect of Wnt signaling on its localization, molecular size, and activity in vivo.

Schaefer KN, Bonello TT, Zhang S, Williams CE, Roberts DM, McKay DJ, Peifer M. Schaefer KN, et al. Among authors: roberts dm. PLoS Genet. 2018 Apr 11;14(4):e1007339. doi: 10.1371/journal.pgen.1007339. eCollection 2018 Apr. PLoS Genet. 2018. PMID: 29641560 Free PMC article.

9

Deconstructing the ßcatenin destruction complex: mechanistic roles for the tumor suppressor APC in regulating Wnt signaling.

Roberts DM, Pronobis MI, Poulton JS, Waldmann JD, Stephenson EM, Hanna S, Peifer M. Roberts DM, et al. Mol Biol Cell. 2011 Jun 1;22(11):1845-63. doi: 10.1091/mbc.E10-11-0871. Epub 2011 Apr 6. Mol Biol Cell. 2011. PMID: 21471006 Free PMC article.

10

Regulation of Wnt signaling by the tumor suppressor adenomatous polyposis coli does not require the ability to enter the nucleus or a particular cytoplasmic localization.

Roberts DM, Pronobis MI, Poulton JS, Kane EG, Peifer M. Roberts DM, et al. Mol Biol Cell. 2012 Jun;23(11):2041-56. doi: 10.1091/mbc.E11-11-0965. Epub 2012 Apr 18. Mol Biol Cell. 2012. PMID: 22513088 Free PMC article.

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