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Reaching for mechanistic consensus across life kingdoms: structure and insights into catalysis of the myo-inositol-1-phosphate synthase (mIPS) from Archaeoglobus fulgidus.
Stieglitz KA, Yang H, Roberts MF, Stec B. Stieglitz KA, et al. Among authors: roberts mf. Biochemistry. 2005 Jan 11;44(1):213-24. doi: 10.1021/bi048267o. Biochemistry. 2005. PMID: 15628862
Cytotoxic amphiphiles and phosphoinositides bind to two discrete sites on the Akt1 PH domain.
Gradziel CS, Wang Y, Stec B, Redfield AG, Roberts MF. Gradziel CS, et al. Among authors: roberts mf. Biochemistry. 2014 Jan 28;53(3):462-72. doi: 10.1021/bi401720v. Epub 2014 Jan 10. Biochemistry. 2014. PMID: 24383815
Role of helix B residues in interfacial activation of a bacterial phosphatidylinositol-specific phospholipase C.
Guo S, Zhang X, Seaton BA, Roberts MF. Guo S, et al. Among authors: roberts mf. Biochemistry. 2008 Apr 8;47(14):4201-10. doi: 10.1021/bi702269u. Epub 2008 Mar 18. Biochemistry. 2008. PMID: 18345643 Free PMC article.
Structure of the S. aureus PI-specific phospholipase C reveals modulation of active site access by a titratable π-cation latched loop.
Goldstein R, Cheng J, Stec B, Roberts MF. Goldstein R, et al. Among authors: roberts mf. Biochemistry. 2012 Mar 27;51(12):2579-87. doi: 10.1021/bi300057q. Epub 2012 Mar 16. Biochemistry. 2012. PMID: 22390775 Free PMC article.
Dissection of the steps of phospholipase C beta 2 activity that are enhanced by G beta gamma subunits.
Feng J, Roberts MF, Drin G, Scarlata S. Feng J, et al. Among authors: roberts mf. Biochemistry. 2005 Feb 22;44(7):2577-84. doi: 10.1021/bi0482607. Biochemistry. 2005. PMID: 15709770
Mobile loop mutations in an archaeal inositol monophosphatase: modulating three-metal ion assisted catalysis and lithium inhibition.
Li Z, Stieglitz KA, Shrout AL, Wei Y, Weis RM, Stec B, Roberts MF. Li Z, et al. Among authors: roberts mf. Protein Sci. 2010 Feb;19(2):309-18. doi: 10.1002/pro.315. Protein Sci. 2010. PMID: 20027624 Free PMC article.
Probing the mechanism of the Archaeoglobus fulgidus inositol-1-phosphate synthase.
Neelon K, Wang Y, Stec B, Roberts MF. Neelon K, et al. Among authors: roberts mf. J Biol Chem. 2005 Mar 25;280(12):11475-82. doi: 10.1074/jbc.M500469200. Epub 2005 Jan 14. J Biol Chem. 2005. PMID: 15653679
Unexpected similarity in regulation between an archaeal inositol monophosphatase/fructose bisphosphatase and chloroplast fructose bisphosphatase.
Stieglitz KA, Seaton BA, Head JF, Stec B, Roberts MF. Stieglitz KA, et al. Among authors: roberts mf. Protein Sci. 2003 Apr;12(4):760-7. doi: 10.1110/ps.0236003. Protein Sci. 2003. PMID: 12649434 Free PMC article.
Enzymology with a spin-labeled phospholipase C: soluble substrate binding by 31P NMR from 0.005 to 11.7 T.
Pu M, Feng J, Redfield AG, Roberts MF. Pu M, et al. Among authors: roberts mf. Biochemistry. 2009 Sep 8;48(35):8282-4. doi: 10.1021/bi901190j. Biochemistry. 2009. PMID: 19663462 Free PMC article.
Crystal structure of the tetrameric inositol 1-phosphate phosphatase (TM1415) from the hyperthermophile, Thermotoga maritima.
Stieglitz KA, Roberts MF, Li W, Stec B. Stieglitz KA, et al. Among authors: roberts mf. FEBS J. 2007 May;274(10):2461-9. doi: 10.1111/j.0014-2956.2007.05779.x. Epub 2007 Apr 10. FEBS J. 2007. PMID: 17419729
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