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A peroxisome proliferator-activated receptor-alpha (PPARalpha) cDNA cloned from guinea-pig liver encodes a protein with similar properties to the mouse PPARalpha: implications for species differences in responses to peroxisome proliferators.
Tugwood JD, Holden PR, James NH, Prince RA, Roberts RA. Tugwood JD, et al. Among authors: roberts ra. Arch Toxicol. 1998 Feb;72(3):169-77. doi: 10.1007/s002040050483. Arch Toxicol. 1998. PMID: 9520140
Role of cytokines in non-genotoxic hepatocarcinogenesis: cause or effect?
Roberts RA, James NH, Cosulich S, Hasmall SC, Orphanides G. Roberts RA, et al. Toxicol Lett. 2001 Mar 31;120(1-3):301-6. doi: 10.1016/s0378-4274(01)00282-x. Toxicol Lett. 2001. PMID: 11323188 Review.
Apoptosis and proliferation in nongenotoxic carcinogenesis: species differences and role of PPARalpha.
Roberts RA, James NH, Hasmall SC, Holden PR, Lambe K, Macdonald N, West D, Woodyatt NJ, Whitcome D. Roberts RA, et al. Toxicol Lett. 2000 Mar 15;112-113:49-57. doi: 10.1016/s0378-4274(99)00243-x. Toxicol Lett. 2000. PMID: 10720712 Review.
The role of protein kinase B and mitogen-activated protein kinase in epidermal growth factor and tumor necrosis factor alpha-mediated rat hepatocyte survival and apoptosis.
Roberts RA, James NH, Cosulich SC. Roberts RA, et al. Hepatology. 2000 Feb;31(2):420-7. doi: 10.1002/hep.510310223. Hepatology. 2000. PMID: 10655266
Species differences in sequence and activity of the peroxisome proliferator response element (PPRE) within the acyl CoA oxidase gene promoter.
Lambe KG, Woodyatt NJ, Macdonald N, Chevalier S, Roberts RA. Lambe KG, et al. Among authors: roberts ra. Toxicol Lett. 1999 Oct 29;110(1-2):119-27. doi: 10.1016/s0378-4274(99)00151-4. Toxicol Lett. 1999. PMID: 10593603
Cytokines in non-genotoxic hepatocarcinogenesis.
Roberts RA, Kimber I. Roberts RA, et al. Carcinogenesis. 1999 Aug;20(8):1397-401. doi: 10.1093/carcin/20.8.1397. Carcinogenesis. 1999. PMID: 10426783 No abstract available.
The perturbation of apoptosis and mitosis by drugs and xenobiotics.
Hasmall SC, Roberts RA. Hasmall SC, et al. Among authors: roberts ra. Pharmacol Ther. 1999 Apr;82(1):63-70. doi: 10.1016/s0163-7258(98)00058-8. Pharmacol Ther. 1999. PMID: 10341357 Review.
The peroxisome proliferator (PP) response element upstream of the human acyl CoA oxidase gene is inactive among a sample human population: significance for species differences in response to PPs.
Woodyatt NJ, Lambe KG, Myers KA, Tugwood JD, Roberts RA. Woodyatt NJ, et al. Among authors: roberts ra. Carcinogenesis. 1999 Mar;20(3):369-72. doi: 10.1093/carcin/20.3.369. Carcinogenesis. 1999. PMID: 10190548
Report on Zeneca Central Toxicology Laboratory (CTL) seminar entitled 'The scientific and practical basis for thresholds in biology' held at CTL, Alderley Park, Cheshire, UK, 26-27th January 1998.
Roberts RA. Roberts RA. Hum Exp Toxicol. 1998 May;17(5):278-82. doi: 10.1177/096032719801700513. Hum Exp Toxicol. 1998. PMID: 9663938 No abstract available.
Expression of the immediate-early genes, c-fos, c-jun, and c-myc: a comparison in rats of nongenotoxic hepatocarcinogens with noncarcinogenic liver mitogens.
Hasmall SC, Pyrah IT, Soames AR, Roberts RA. Hasmall SC, et al. Among authors: roberts ra. Fundam Appl Toxicol. 1997 Nov;40(1):129-37. doi: 10.1006/faat.1997.2371. Fundam Appl Toxicol. 1997. PMID: 9398495
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