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M-CSF, TNFalpha and RANK ligand promote osteoclast survival by signaling through mTOR/S6 kinase.
Glantschnig H, Fisher JE, Wesolowski G, Rodan GA, Reszka AA. Glantschnig H, et al. Among authors: rodan ga. Cell Death Differ. 2003 Oct;10(10):1165-77. doi: 10.1038/sj.cdd.4401285. Cell Death Differ. 2003. PMID: 14502240
Regulatory mechanism of osteoclast activation.
Nakamura I, Rodan GA, Duong LT. Nakamura I, et al. Among authors: rodan ga. J Electron Microsc (Tokyo). 2003;52(6):527-33. doi: 10.1093/jmicro/52.6.527. J Electron Microsc (Tokyo). 2003. PMID: 14756240 Review.
PYK2 autophosphorylation, but not kinase activity, is necessary for adhesion-induced association with c-Src, osteoclast spreading, and bone resorption.
Lakkakorpi PT, Bett AJ, Lipfert L, Rodan GA, Duong LT. Lakkakorpi PT, et al. Among authors: rodan ga. J Biol Chem. 2003 Mar 28;278(13):11502-12. doi: 10.1074/jbc.M206579200. Epub 2003 Jan 3. J Biol Chem. 2003. PMID: 12514172
The LATS2/KPM tumor suppressor is a negative regulator of the androgen receptor.
Powzaniuk M, McElwee-Witmer S, Vogel RL, Hayami T, Rutledge SJ, Chen F, Harada S, Schmidt A, Rodan GA, Freedman LP, Bai C. Powzaniuk M, et al. Among authors: rodan ga. Mol Endocrinol. 2004 Aug;18(8):2011-23. doi: 10.1210/me.2004-0065. Epub 2004 May 6. Mol Endocrinol. 2004. PMID: 15131260
Agonist-like SERM effects on ERalpha-mediated repression of MMP1 promoter activity predict in vivo effects on bone and uterus.
Scafonas A, Reszka AA, Kimmel DB, Hou XS, Su Q, Birzin ET, Kim S, Chen HY, Tan Q, Roher SP, Dininno F, Hammond ML, Rodan GA, Towler DA, Schmidt A. Scafonas A, et al. Among authors: rodan ga. J Steroid Biochem Mol Biol. 2008 Jun;110(3-5):197-206. doi: 10.1016/j.jsbmb.2007.10.013. Epub 2008 Apr 20. J Steroid Biochem Mol Biol. 2008. PMID: 18508261
Relative binding affinities of bisphosphonates for human bone and relationship to antiresorptive efficacy.
Leu CT, Luegmayr E, Freedman LP, Rodan GA, Reszka AA. Leu CT, et al. Among authors: rodan ga. Bone. 2006 May;38(5):628-36. doi: 10.1016/j.bone.2005.07.023. Epub 2005 Sep 26. Bone. 2006. PMID: 16185944
Mechanism of action of bisphosphonates.
Reszka AA, Rodan GA. Reszka AA, et al. Among authors: rodan ga. Curr Osteoporos Rep. 2003 Sep;1(2):45-52. doi: 10.1007/s11914-003-0008-5. Curr Osteoporos Rep. 2003. PMID: 16036064 Review.
The role of subchondral bone remodeling in osteoarthritis: reduction of cartilage degeneration and prevention of osteophyte formation by alendronate in the rat anterior cruciate ligament transection model.
Hayami T, Pickarski M, Wesolowski GA, McLane J, Bone A, Destefano J, Rodan GA, Duong LT. Hayami T, et al. Among authors: rodan ga. Arthritis Rheum. 2004 Apr;50(4):1193-206. doi: 10.1002/art.20124. Arthritis Rheum. 2004. PMID: 15077302
Distinct roles of p130Cas and c-Cbl in adhesion-induced or macrophage colony-stimulating factor-mediated signaling pathways in prefusion osteoclasts.
Nakamura I, Rodan GA, Duong LT. Nakamura I, et al. Among authors: rodan ga. Endocrinology. 2003 Nov;144(11):4739-41. doi: 10.1210/en.2003-0615. Epub 2003 Aug 13. Endocrinology. 2003. PMID: 12959979
Control of osteoblast function and regulation of bone mass.
Harada S, Rodan GA. Harada S, et al. Among authors: rodan ga. Nature. 2003 May 15;423(6937):349-55. doi: 10.1038/nature01660. Nature. 2003. PMID: 12748654 Review.
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