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Exome sequencing implicates an increased burden of rare potassium channel variants in the risk of drug-induced long QT interval syndrome.
Weeke P, Mosley JD, Hanna D, Delaney JT, Shaffer C, Wells QS, Van Driest S, Karnes JH, Ingram C, Guo Y, Shyr Y, Norris K, Kannankeril PJ, Ramirez AH, Smith JD, Mardis ER, Nickerson D, George AL Jr, Roden DM. Weeke P, et al. Among authors: roden dm. J Am Coll Cardiol. 2014 Apr 15;63(14):1430-7. doi: 10.1016/j.jacc.2014.01.031. Epub 2014 Feb 19. J Am Coll Cardiol. 2014. PMID: 24561134 Free PMC article.
Cardiac ion channels.
Roden DM, Balser JR, George AL Jr, Anderson ME. Roden DM, et al. Annu Rev Physiol. 2002;64:431-75. doi: 10.1146/annurev.physiol.64.083101.145105. Annu Rev Physiol. 2002. PMID: 11826275 Review.
Drug-induced prolongation of the QT interval.
Roden DM. Roden DM. N Engl J Med. 2004 Mar 4;350(10):1013-22. doi: 10.1056/NEJMra032426. N Engl J Med. 2004. PMID: 14999113 Review. No abstract available.
802 results