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Adapting dCas9-APEX2 for subnuclear proteomic profiling.
Gao XD, Rodríguez TC, Sontheimer EJ. Gao XD, et al. Among authors: rodriguez tc. Methods Enzymol. 2019;616:365-383. doi: 10.1016/bs.mie.2018.10.030. Epub 2018 Dec 10. Methods Enzymol. 2019. PMID: 30691651 Free PMC article.
An engineered ScCas9 with broad PAM range and high specificity and activity.
Chatterjee P, Jakimo N, Lee J, Amrani N, Rodríguez T, Koseki SRT, Tysinger E, Qing R, Hao S, Sontheimer EJ, Jacobson J. Chatterjee P, et al. Nat Biotechnol. 2020 Oct;38(10):1154-1158. doi: 10.1038/s41587-020-0517-0. Epub 2020 May 11. Nat Biotechnol. 2020. PMID: 32393822
Genome-wide detection and analysis of CRISPR-Cas off-targets.
Rodríguez TC, Dadafarin S, Pratt HE, Liu P, Amrani N, Zhu LJ. Rodríguez TC, et al. Prog Mol Biol Transl Sci. 2021;181:31-43. doi: 10.1016/bs.pmbts.2021.01.012. Epub 2021 Mar 4. Prog Mol Biol Transl Sci. 2021. PMID: 34127199
Androgen Activity Is Associated With PD-L1 Downregulation in Thyroid Cancer.
O'Connell TJ, Dadafarin S, Jones M, Rodríguez T, Gupta A, Shin E, Moscatello A, Iacob C, Islam H, Tiwari RK, Geliebter J. O'Connell TJ, et al. Front Cell Dev Biol. 2021 Aug 6;9:663130. doi: 10.3389/fcell.2021.663130. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34422798 Free PMC article.
Self-inactivating, all-in-one AAV vectors for precision Cas9 genome editing via homology-directed repair in vivo.
Ibraheim R, Tai PWL, Mir A, Javeed N, Wang J, Rodríguez TC, Namkung S, Nelson S, Khokhar ES, Mintzer E, Maitland S, Chen Z, Cao Y, Tsagkaraki E, Wolfe SA, Wang D, Pai AA, Xue W, Gao G, Sontheimer EJ. Ibraheim R, et al. Among authors: rodriguez tc. Nat Commun. 2021 Nov 1;12(1):6267. doi: 10.1038/s41467-021-26518-y. Nat Commun. 2021. PMID: 34725353 Free PMC article.
CRISPR-enhanced human adipocyte browning as cell therapy for metabolic disease.
Tsagkaraki E, Nicoloro SM, DeSouza T, Solivan-Rivera J, Desai A, Lifshitz LM, Shen Y, Kelly M, Guilherme A, Henriques F, Amrani N, Ibraheim R, Rodriguez TC, Luk K, Maitland S, Friedline RH, Tauer L, Hu X, Kim JK, Wolfe SA, Sontheimer EJ, Corvera S, Czech MP. Tsagkaraki E, et al. Among authors: rodriguez tc. Nat Commun. 2021 Nov 26;12(1):6931. doi: 10.1038/s41467-021-27190-y. Nat Commun. 2021. PMID: 34836963 Free PMC article.
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