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pRB-Depleted Pluripotent Stem Cell Retinal Organoids Recapitulate Cell State Transitions of Retinoblastoma Development and Suggest an Important Role for pRB in Retinal Cell Differentiation.
Rozanska A, Cerna-Chavez R, Queen R, Collin J, Zerti D, Dorgau B, Beh CS, Davey T, Coxhead J, Hussain R, Al-Aama J, Steel DH, Benvenisty N, Armstrong L, Parulekar M, Lako M. Rozanska A, et al. Among authors: cerna chavez r. Stem Cells Transl Med. 2022 Apr 29;11(4):415-433. doi: 10.1093/stcltm/szac008. Stem Cells Transl Med. 2022. PMID: 35325233 Free PMC article.
Retinal cells derived from patients with DRAM2-dependent CORD21 dystrophy exhibit key lysosomal enzyme deficiency and lysosomal content accumulation.
Tsikandelova R, Galo E, Cerniauskas E, Hallam D, Georgiou M, Cerna-Chavez R, Atkinson R, Palmowski P, Burté F, Davies T, Steel DH, McKibbin M, Bond J, Haggarty J, Whitfield P, Korolchuk V, Armstrong L, Yang C, Dorgau B, Kurzawa-Akanbi M, Lako M. Tsikandelova R, et al. Among authors: cerna chavez r. Stem Cell Reports. 2024 Aug 13;19(8):1107-1121. doi: 10.1016/j.stemcr.2024.06.002. Epub 2024 Jul 3. Stem Cell Reports. 2024. PMID: 38964324 Free PMC article.