Rodrigues AD - Search Results

1

In-vitro metabolism of celecoxib, a cyclooxygenase-2 inhibitor, by allelic variant forms of human liver microsomal cytochrome P450 2C9: correlation with CYP2C9 genotype and in-vivo pharmacokinetics.

Tang C, Shou M, Rushmore TH, Mei Q, Sandhu P, Woolf EJ, Rose MJ, Gelmann A, Greenberg HE, De Lepeleire I, Van Hecken A, De Schepper PJ, Ebel DL, Schwartz JI, Rodrigues AD. Tang C, et al. Among authors: rodrigues ad. Pharmacogenetics. 2001 Apr;11(3):223-35. doi: 10.1097/00008571-200104000-00006. Pharmacogenetics. 2001. PMID: 11337938

2

Comparison of levels of aldehyde oxidase with cytochrome P450 activities in human liver in vitro.

Rodrigues AD. Rodrigues AD. Biochem Pharmacol. 1994 Jul 5;48(1):197-200. doi: 10.1016/0006-2952(94)90240-2. Biochem Pharmacol. 1994. PMID: 8043023

3

Identification of the human liver cytochrome P450 enzymes involved in the metabolism of zileuton (ABT-077) and its N-dehydroxylated metabolite, Abbott-66193.

Machinist JM, Mayer MD, Shet MS, Ferrero JL, Rodrigues AD. Machinist JM, et al. Among authors: rodrigues ad. Drug Metab Dispos. 1995 Oct;23(10):1163-74. Drug Metab Dispos. 1995. PMID: 8654206

4

[O-methyl 14C]naproxen O-demethylase activity in human liver microsomes: evidence for the involvement of cytochrome P4501A2 and P4502C9/10.

Rodrigues AD, Kukulka MJ, Roberts EM, Ouellet D, Rodgers TR. Rodrigues AD, et al. Drug Metab Dispos. 1996 Jan;24(1):126-36. Drug Metab Dispos. 1996. PMID: 8825200

5

Oxidative metabolism of clarithromycin in the presence of human liver microsomes. Major role for the cytochrome P4503A (CYP3A) subfamily.

Rodrigues AD, Roberts EM, Mulford DJ, Yao Y, Ouellet D. Rodrigues AD, et al. Drug Metab Dispos. 1997 May;25(5):623-30. Drug Metab Dispos. 1997. PMID: 9152603

6

The in vitro interaction of dexmedetomidine with human liver microsomal cytochrome P4502D6 (CYP2D6).

Rodrigues AD, Roberts EM. Rodrigues AD, et al. Drug Metab Dispos. 1997 May;25(5):651-5. Drug Metab Dispos. 1997. PMID: 9152607

7

Identification of the human liver cytochrome P450 enzymes involved in the in vitro metabolism of a novel 5-lipoxygenase inhibitor.

Machinist JM, Mayer MD, Roberts EM, Surber BW, Rodrigues AD. Machinist JM, et al. Among authors: rodrigues ad. Drug Metab Dispos. 1998 Oct;26(10):970-6. Drug Metab Dispos. 1998. PMID: 9763401

8

Integrated cytochrome P450 reaction phenotyping: attempting to bridge the gap between cDNA-expressed cytochromes P450 and native human liver microsomes.

Rodrigues AD. Rodrigues AD. Biochem Pharmacol. 1999 Mar 1;57(5):465-80. doi: 10.1016/s0006-2952(98)00268-8. Biochem Pharmacol. 1999. PMID: 9952310 Review.

9

Role of a potent inhibitory monoclonal antibody to cytochrome P-450 3A4 in assessment of human drug metabolism.

Mei Q, Tang C, Assang C, Lin Y, Slaughter D, Rodrigues AD, Baillie TA, Rushmore TH, Shou M. Mei Q, et al. Among authors: rodrigues ad. J Pharmacol Exp Ther. 1999 Nov;291(2):749-59. J Pharmacol Exp Ther. 1999. PMID: 10525096

10

Substrate-dependent effect of acetonitrile on human liver microsomal cytochrome P450 2C9 (CYP2C9) activity.

Tang C, Shou M, Rodrigues AD. Tang C, et al. Among authors: rodrigues ad. Drug Metab Dispos. 2000 May;28(5):567-72. Drug Metab Dispos. 2000. PMID: 10772636

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