Rodrigues AD - Search Results

1

Preclinical drug metabolism in the age of high-throughput screening: an industrial perspective.

Rodrigues AD. Rodrigues AD. Pharm Res. 1997 Nov;14(11):1504-10. doi: 10.1023/a:1012105713585. Pharm Res. 1997. PMID: 9434267 Review.

2

Role of human liver cytochrome P4503A in the metabolism of etoricoxib, a novel cyclooxygenase-2 selective inhibitor.

Kassahun K, McIntosh IS, Shou M, Walsh DJ, Rodeheffer C, Slaughter DE, Geer LA, Halpin RA, Agrawal N, Rodrigues AD. Kassahun K, et al. Among authors: rodrigues ad. Drug Metab Dispos. 2001 Jun;29(6):813-20. Drug Metab Dispos. 2001. PMID: 11353749

3

Use of in vitro drug metabolism data to evaluate metabolic drug-drug interactions in man: the need for quantitative databases.

Rodrigues AD, Winchell GA, Dobrinska MR. Rodrigues AD, et al. J Clin Pharmacol. 2001 Apr;41(4):368-73. doi: 10.1177/00912700122010212. J Clin Pharmacol. 2001. PMID: 11304892

4

The potential for CYP2D6 inhibition screening using a novel scintillation proximity assay-based approach.

Delaporte E, Slaughter DE, Egan MA, Gatto GJ, Santos A, Shelley J, Price E, Howells L, Dean DC, Rodrigues AD. Delaporte E, et al. Among authors: rodrigues ad. J Biomol Screen. 2001 Aug;6(4):225-31. doi: 10.1177/108705710100600404. J Biomol Screen. 2001. PMID: 11689122

5

Screening of drug candidates for their drug--drug interaction potential.

Rodrigues AD, Lin JH. Rodrigues AD, et al. Curr Opin Chem Biol. 2001 Aug;5(4):396-401. doi: 10.1016/s1367-5931(00)00220-9. Curr Opin Chem Biol. 2001. PMID: 11470602 Review.

6

Role of a potent inhibitory monoclonal antibody to cytochrome P-450 3A4 in assessment of human drug metabolism.

Mei Q, Tang C, Assang C, Lin Y, Slaughter D, Rodrigues AD, Baillie TA, Rushmore TH, Shou M. Mei Q, et al. Among authors: rodrigues ad. J Pharmacol Exp Ther. 1999 Nov;291(2):749-59. J Pharmacol Exp Ther. 1999. PMID: 10525096

7

Application of human liver microsomes in metabolism-based drug-drug interactions: in vitro-in vivo correlations and the Abbott Laboratories experience.

Rodrigues AD, Wong SL. Rodrigues AD, et al. Adv Pharmacol. 1997;43:65-101. doi: 10.1016/s1054-3589(08)60202-1. Adv Pharmacol. 1997. PMID: 9342173 Review. No abstract available.

8

Use of in vitro human metabolism studies in drug development. An industrial perspective.

Rodrigues AD. Rodrigues AD. Biochem Pharmacol. 1994 Dec 16;48(12):2147-56. doi: 10.1016/0006-2952(94)00312-2. Biochem Pharmacol. 1994. PMID: 7811296 No abstract available.

9

Integrated cytochrome P450 reaction phenotyping: attempting to bridge the gap between cDNA-expressed cytochromes P450 and native human liver microsomes.

Rodrigues AD. Rodrigues AD. Biochem Pharmacol. 1999 Mar 1;57(5):465-80. doi: 10.1016/s0006-2952(98)00268-8. Biochem Pharmacol. 1999. PMID: 9952310 Review.

10

Enzyme kinetics of cytochrome P450-mediated reactions.

Shou M, Lin Y, Lu P, Tang C, Mei Q, Cui D, Tang W, Ngui JS, Lin CC, Singh R, Wong BK, Yergey JA, Lin JH, Pearson PG, Baillie TA, Rodrigues AD, Rushmore TH. Shou M, et al. Among authors: rodrigues ad. Curr Drug Metab. 2001 Mar;2(1):17-36. doi: 10.2174/1389200013338784. Curr Drug Metab. 2001. PMID: 11465149 Review.

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