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Six9 (Optx2), a new member of the six gene family of transcription factors, is expressed at early stages of vertebrate ocular and pituitary development.
López-Ríos J, Gallardo ME, Rodriguez de Córdoba S, Bovolenta P. López-Ríos J, et al. Mech Dev. 1999 May;83(1-2):155-9. doi: 10.1016/s0925-4773(99)00017-9. Mech Dev. 1999. PMID: 10381575
Genomic cloning and characterization of the human homeobox gene SIX6 reveals a cluster of SIX genes in chromosome 14 and associates SIX6 hemizygosity with bilateral anophthalmia and pituitary anomalies.
Gallardo ME, Lopez-Rios J, Fernaud-Espinosa I, Granadino B, Sanz R, Ramos C, Ayuso C, Seller MJ, Brunner HG, Bovolenta P, Rodríguez de Córdoba S. Gallardo ME, et al. Genomics. 1999 Oct 1;61(1):82-91. doi: 10.1006/geno.1999.5916. Genomics. 1999. PMID: 10512683
Genomic cloning, structure, expression pattern, and chromosomal location of the human SIX3 gene.
Granadino B, Gallardo ME, López-Ríos J, Sanz R, Ramos C, Ayuso C, Bovolenta P, Rodríguez de Córdoba S. Granadino B, et al. Genomics. 1999 Jan 1;55(1):100-5. doi: 10.1006/geno.1998.5611. Genomics. 1999. PMID: 9889003
The human homogentisate 1,2-dioxygenase (HGO) gene.
Granadino B, Beltrán-Valero de Bernabé D, Fernández-Cañón JM, Peñalva MA, Rodríguez de Córdoba S. Granadino B, et al. Genomics. 1997 Jul 15;43(2):115-22. doi: 10.1006/geno.1997.4805. Genomics. 1997. PMID: 9244427
Sequence and structure of the human 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase heart isoform gene (PFKFB2).
Heine-Suñer D, Díaz-Guillén MA, Lange AJ, Rodríguez de Córdoba S. Heine-Suñer D, et al. Eur J Biochem. 1998 May 15;254(1):103-10. doi: 10.1046/j.1432-1327.1998.2540103.x. Eur J Biochem. 1998. PMID: 9652401
An integrated map of the human regulator of complement activation (RCA) gene cluster on 1q32.
Rodríguez de Córdoba S, Díaz-Guillén MA, Heine-Suñer D. Rodríguez de Córdoba S, et al. Mol Immunol. 1999 Sep-Oct;36(13-14):803-8. doi: 10.1016/s0161-5890(99)00100-5. Mol Immunol. 1999. PMID: 10698333 No abstract available.
The human CD53 gene, coding for a four transmembrane domain protein, maps to chromosomal region 1p13.
Gonzalez ME, Pardo-Manuel de Villena F, Fernandez-Ruiz E, Rodriguez de Cordoba S, Lazo PA. Gonzalez ME, et al. Genomics. 1993 Dec;18(3):725-8. doi: 10.1016/s0888-7543(05)80385-4. Genomics. 1993. PMID: 8307585 No abstract available.
The gene coding for the beta-chain of C4b-binding protein (C4BPB) has become a pseudogene in the mouse.
Rodríguez de Córdoba S, Pérez-Blas M, Ramos-Ruiz R, Sánchez-Corral P, Pardo-Manuel de Villena F, Rey-Campos J. Rodríguez de Córdoba S, et al. Genomics. 1994 Jun;21(3):501-9. doi: 10.1006/geno.1994.1308. Genomics. 1994. PMID: 7959726
C4BP beta binds the anticoagulant vitamin K-dependent protein S. Two, nonmutually exclusive, roles have been proposed for the C4BP-protein S interaction. ...While the physiological significance of C4BP-protein S interaction is unclear, it has clinical relevan …
C4BP beta binds the anticoagulant vitamin K-dependent protein S. Two, nonmutually exclusive, roles have been proposed for the C4BP-pr …
Molecular analyses of the HGO gene mutations in Turkish alkaptonuria patients suggest that the R58fs mutation originated from central Asia and was spread throughout Europe and Anatolia by human migrations.
Uyguner O, Goicoechea de Jorge E, Cefle A, Baykal T, Kayserili H, Cefle K, Demirkol M, Yuksel-Apak M, Rodriguez de Córdoba S, Wollnik B. Uyguner O, et al. J Inherit Metab Dis. 2003;26(1):17-23. doi: 10.1023/a:1024063126954. J Inherit Metab Dis. 2003. PMID: 12872836 Clinical Trial.
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