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Resveratrol induces colon tumor cell apoptosis independently of p53 and precede by epithelial differentiation, mitochondrial proliferation and membrane potential collapse.
Mahyar-Roemer M, Katsen A, Mestres P, Roemer K. Mahyar-Roemer M, et al. Among authors: roemer k. Int J Cancer. 2001 Dec 1;94(5):615-22. doi: 10.1002/ijc.1516. Int J Cancer. 2001. PMID: 11745454
Resistance of mitochondrial p53 to dominant inhibition.
Heyne K, Schmitt K, Mueller D, Armbruester V, Mestres P, Roemer K. Heyne K, et al. Among authors: roemer k. Mol Cancer. 2008 Jun 12;7:54. doi: 10.1186/1476-4598-7-54. Mol Cancer. 2008. PMID: 18547443 Free PMC article.
A novel mechanism of crosstalk between the p53 and NFκB pathways: MDM2 binds and inhibits p65RelA.
Heyne K, Winter C, Gerten F, Schmidt C, Roemer K. Heyne K, et al. Among authors: roemer k. Cell Cycle. 2013 Aug 1;12(15):2479-92. doi: 10.4161/cc.25495. Epub 2013 Jun 28. Cell Cycle. 2013. PMID: 23839035 Free PMC article.
Frequent nonrandom activation of germ-line genes in human cancer.
Koslowski M, Bell C, Seitz G, Lehr HA, Roemer K, Müntefering H, Huber C, Sahin U, Türeci O. Koslowski M, et al. Among authors: roemer k. Cancer Res. 2004 Sep 1;64(17):5988-93. doi: 10.1158/0008-5472.CAN-04-1187. Cancer Res. 2004. PMID: 15342378
Differentiation of human alveolar epithelial cells in primary culture: morphological characterization and synthesis of caveolin-1 and surfactant protein-C.
Fuchs S, Hollins AJ, Laue M, Schaefer UF, Roemer K, Gumbleton M, Lehr CM. Fuchs S, et al. Among authors: roemer k. Cell Tissue Res. 2003 Jan;311(1):31-45. doi: 10.1007/s00441-002-0653-5. Epub 2002 Nov 12. Cell Tissue Res. 2003. PMID: 12483282
Human endogenous retrovirus rec interferes with germ cell development in mice and may cause carcinoma in situ, the predecessor lesion of germ cell tumors.
Galli UM, Sauter M, Lecher B, Maurer S, Herbst H, Roemer K, Mueller-Lantzsch N. Galli UM, et al. Among authors: roemer k. Oncogene. 2005 Apr 28;24(19):3223-8. doi: 10.1038/sj.onc.1208543. Oncogene. 2005. PMID: 15735668
The basis for the chemopreventive action of resveratrol.
Roemer K, Mahyar-Roemer M. Roemer K, et al. Drugs Today (Barc). 2002 Aug;38(8):571-80. doi: 10.1358/dot.2002.38.8.820097. Drugs Today (Barc). 2002. PMID: 12582422 Review.
No anti-apoptotic effects of single copies of mutant p53 genes in drug-treated tumor cells.
Fritzsche C, Zeller G, Knaup KX, Roemer K. Fritzsche C, et al. Among authors: roemer k. Anticancer Drugs. 2004 Aug;15(7):679-88. doi: 10.1097/01.cad.0000136878.96680.f5. Anticancer Drugs. 2004. PMID: 15269599
Role of Bax in resveratrol-induced apoptosis of colorectal carcinoma cells.
Mahyar-Roemer M, Köhler H, Roemer K. Mahyar-Roemer M, et al. Among authors: roemer k. BMC Cancer. 2002 Oct 17;2:27. doi: 10.1186/1471-2407-2-27. BMC Cancer. 2002. PMID: 12383351 Free PMC article.
A novel gene from the human endogenous retrovirus K expressed in transformed cells.
Armbruester V, Sauter M, Krautkraemer E, Meese E, Kleiman A, Best B, Roemer K, Mueller-Lantzsch N. Armbruester V, et al. Among authors: roemer k. Clin Cancer Res. 2002 Jun;8(6):1800-7. Clin Cancer Res. 2002. PMID: 12060620