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Genome-wide fitness test and mechanism-of-action studies of inhibitory compounds in Candida albicans.
Xu D, Jiang B, Ketela T, Lemieux S, Veillette K, Martel N, Davison J, Sillaots S, Trosok S, Bachewich C, Bussey H, Youngman P, Roemer T. Xu D, et al. PLoS Pathog. 2007 Jun;3(6):e92. doi: 10.1371/journal.ppat.0030092. PLoS Pathog. 2007. PMID: 17604452 Free PMC article.
Pathway analysis of Candida albicans survival and virulence determinants in a murine infection model.
Becker JM, Kauffman SJ, Hauser M, Huang L, Lin M, Sillaots S, Jiang B, Xu D, Roemer T. Becker JM, et al. Proc Natl Acad Sci U S A. 2010 Dec 21;107(51):22044-9. doi: 10.1073/pnas.1009845107. Epub 2010 Dec 6. Proc Natl Acad Sci U S A. 2010. PMID: 21135205 Free PMC article.
Chemical Genetic Analysis and Functional Characterization of Staphylococcal Wall Teichoic Acid 2-Epimerases Reveals Unconventional Antibiotic Drug Targets.
Mann PA, Müller A, Wolff KA, Fischmann T, Wang H, Reed P, Hou Y, Li W, Müller CE, Xiao J, Murgolo N, Sher X, Mayhood T, Sheth PR, Mirza A, Labroli M, Xiao L, McCoy M, Gill CJ, Pinho MG, Schneider T, Roemer T. Mann PA, et al. PLoS Pathog. 2016 May 4;12(5):e1005585. doi: 10.1371/journal.ppat.1005585. eCollection 2016 May. PLoS Pathog. 2016. PMID: 27144276 Free PMC article.
Bugs, drugs and chemical genomics.
Roemer T, Davies J, Giaever G, Nislow C. Roemer T, et al. Nat Chem Biol. 2011 Dec 15;8(1):46-56. doi: 10.1038/nchembio.744. Nat Chem Biol. 2011. PMID: 22173359 Review.
High-frequency transposition for determining antibacterial mode of action.
Wang H, Claveau D, Vaillancourt JP, Roemer T, Meredith TC. Wang H, et al. Nat Chem Biol. 2011 Sep 4;7(10):720-9. doi: 10.1038/nchembio.643. Nat Chem Biol. 2011. PMID: 21892185
Cyclic colisporifungin and linear cavinafungins, antifungal lipopeptides isolated from Colispora cavincola.
Ortíz-López FJ, Monteiro MC, González-Menéndez V, Tormo JR, Genilloud O, Bills GF, Vicente F, Zhang C, Roemer T, Singh SB, Reyes F. Ortíz-López FJ, et al. J Nat Prod. 2015 Mar 27;78(3):468-75. doi: 10.1021/np500854j. Epub 2015 Jan 30. J Nat Prod. 2015. PMID: 25636062
Chemical genetic profiling and characterization of small-molecule compounds that affect the biosynthesis of unsaturated fatty acids in Candida albicans.
Xu D, Sillaots S, Davison J, Hu W, Jiang B, Kauffman S, Martel N, Ocampo P, Oh C, Trosok S, Veillette K, Wang H, Yang M, Zhang L, Becker J, Martin CE, Roemer T. Xu D, et al. J Biol Chem. 2009 Jul 17;284(29):19754-64. doi: 10.1074/jbc.M109.019877. Epub 2009 Jun 1. J Biol Chem. 2009. PMID: 19487691 Free PMC article.
Transcription factor substitution during the evolution of fungal ribosome regulation.
Hogues H, Lavoie H, Sellam A, Mangos M, Roemer T, Purisima E, Nantel A, Whiteway M. Hogues H, et al. Mol Cell. 2008 Mar 14;29(5):552-62. doi: 10.1016/j.molcel.2008.02.006. Mol Cell. 2008. PMID: 18342603 Free PMC article.
Depletion of the cullin Cdc53p induces morphogenetic changes in Candida albicans.
Trunk K, Gendron P, Nantel A, Lemieux S, Roemer T, Raymond M. Trunk K, et al. Eukaryot Cell. 2009 May;8(5):756-67. doi: 10.1128/EC.00332-08. Epub 2009 Mar 6. Eukaryot Cell. 2009. PMID: 19270112 Free PMC article.
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