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Mouse anti-mouse IgD monoclonal antibodies generated in IgD-deficient mice.
Roes J, Müller W, Rajewsky K. Roes J, et al. J Immunol Methods. 1995 Jun 28;183(2):231-7. doi: 10.1016/0022-1759(95)00059-j. J Immunol Methods. 1995. PMID: 7602146
Targeted disruption of the V(H) 81X gene: influence on the B cell repertoire.
Huetz F, Tornberg UC, Malanchère E, Roes J, Carlsson L, Coutinho A, Holmberg D, Rajewsky K. Huetz F, et al. Eur J Immunol. 1997 Jan;27(1):307-14. doi: 10.1002/eji.1830270144. Eur J Immunol. 1997. PMID: 9022033
B lymphocyte-specific, Cre-mediated mutagenesis in mice.
Rickert RC, Roes J, Rajewsky K. Rickert RC, et al. Nucleic Acids Res. 1997 Mar 15;25(6):1317-8. doi: 10.1093/nar/25.6.1317. Nucleic Acids Res. 1997. PMID: 9092650 Free PMC article.
Somatic hypermutation occurs in B cells of terminal deoxynucleotidyl transferase-, CD23-, interleukin-4-, IgD- and CD30-deficient mouse mutants.
Texidó G, Jacobs H, Meiering M, Kühn R, Roes J, Müller W, Gilfillan S, Fujiwara H, Kikutani H, Yoshida N, Amakawa R, Benoist C, Mathis D, Kishimoto T, Mak TW, Rajewsky K. Texidó G, et al. Eur J Immunol. 1996 Aug;26(8):1966-9. doi: 10.1002/eji.1830260843. Eur J Immunol. 1996. PMID: 8765046 No abstract available.
Conditional gene targeting.
Rajewsky K, Gu H, Kühn R, Betz UA, Müller W, Roes J, Schwenk F. Rajewsky K, et al. J Clin Invest. 1996 Aug 1;98(3):600-3. doi: 10.1172/JCI118828. J Clin Invest. 1996. PMID: 8698848 Free PMC article. Review. No abstract available.
Inactivation of the N-CAM gene in mice results in size reduction of the olfactory bulb and deficits in spatial learning.
Cremer H, Lange R, Christoph A, Plomann M, Vopper G, Roes J, Brown R, Baldwin S, Kraemer P, Scheff S, et al. Cremer H, et al. Nature. 1994 Feb 3;367(6462):455-9. doi: 10.1038/367455a0. Nature. 1994. PMID: 8107803
V gene rearrangement is required to fully activate the hypermutation mechanism in B cells.
Roes J, Hüppi K, Rajewsky K, Sablitzky F. Roes J, et al. J Immunol. 1989 Feb 1;142(3):1022-6. J Immunol. 1989. PMID: 2492327
Thus, the hypermutation mechanism operating in B cell differentiation is targeted at V genes rearranged to the J locus and may require nucleotide sequences associated with both V and J elements in order to be fully activated. ...
Thus, the hypermutation mechanism operating in B cell differentiation is targeted at V genes rearranged to the J locus and may requir …
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